CTR2 (YHR175W)


Gene profile

Gene name: CTR2
Reference locus (S288C): YHR175W
Gene biotype: protein_coding

Description: Solute carrier family 31 (copper transporter), member 1; Low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation; regulated by nonsense-mediated mRNA decay pathway

Top 10 interactors (score): CTR3 (0.995); COX17 (0.959); CCC2 (0.954); MAC1 (0.948); FET4 (0.93); SOD1 (0.907); HAA1 (0.907); ATX1 (0.903); FET3 (0.846); CUP2 (0.815); FTR1 (0.808); SCO2 (0.782); FTH1 (0.759); CUP1-2 (0.757); CTR1 (0.755); FRE2 (0.748); FRE1 (0.743); FRE6 (0.733); ZRT1 (0.723); SMF3 (0.718)

Homologues (species, bitscore): SLC31A1 (Homo sapiens, 63.2); Slc31a1 (Mus musculus, 65.1); slc31a1 (Danio rerio, 67.0); Ctr1A (Drosophila melanogaster, 76.6); Y58A7A.1 (Caenorhabditis elegans, 58.9); COPT5 (Arabidopsis thaliana, 54.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:439969-440538:+ gene-YHR175W_AKU4011 rna-NM_001179306.3_AKU4011 cds-NP_012045.3_AKU4011 98.0 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000141.1:77205-77774:- gene-YHR175W_BG1 rna-NM_001179306.3_BG1 cds-NP_012045.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:447210-447779:+ gene-YHR175W_Bruggeman rna-NM_001179306.3_Bruggeman cds-NP_012045.3_Bruggeman 98.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:442611-443180:+ gene-YHR175W_CAT1 rna-NM_001179306.3_CAT1 cds-NP_012045.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:439423-439992:+ gene-YHR175W_CBS1585 rna-NM_001179306.3_CBS1585 cds-NP_012045.3_CBS1585 98.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:436863-437432:+ gene-YHR175W_CBS436 rna-NM_001179306.3_CBS436 cds-NP_012045.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:439506-440075:+ gene-YHR175W_CBS6412 rna-NM_001179306.3_CBS6412 cds-NP_012045.3_CBS6412 98.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:440308-440877:+ gene-YHR175W_CBS6413 rna-NM_001179306.3_CBS6413 cds-NP_012045.3_CBS6413 98.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:446053-446622:+ gene-YHR175W_CENPK1137D rna-NM_001179306.3_CENPK1137D cds-NP_012045.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:498518-499087:+ gene-YHR175W_EthanolRed rna-NM_001179306.3_EthanolRed cds-NP_012045.3_EthanolRed 98.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:440961-441530:+ gene-YHR175W_FaliES1 rna-NM_001179306.3_FaliES1 cds-NP_012045.3_FaliES1 98.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000376.1:13259-13828:- gene-YHR175W_JAY291 rna-NM_001179306.3_JAY291 cds-NP_012045.3_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:448283-448852:+ gene-YHR175W_MUCL30387 rna-NM_001179306.3_MUCL30387 cds-NP_012045.3_MUCL30387 98.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:447722-448291:+ gene-YHR175W_MUCL30388 rna-NM_001179306.3_MUCL30388 cds-NP_012045.3_MUCL30388 98.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:439334-439903:+ gene-YHR175W_MUCL39482 rna-NM_001179306.3_MUCL39482 cds-NP_012045.3_MUCL39482 98.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:445940-446509:+ gene-YHR175W_MUCL42920 rna-NM_001179306.3_MUCL42920 cds-NP_012045.3_MUCL42920 99.1 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:452754-453323:+ gene-YHR175W_NCIM3186 rna-NM_001179306.3_NCIM3186 cds-NP_012045.3_NCIM3186 98.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:441793-442362:+ gene-YHR175W_NCYC1407 rna-NM_001179306.3_NCYC1407 cds-NP_012045.3_NCYC1407 98.0 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:440932-441501:+ gene-YHR175W_PE2H3 rna-NM_001179306.3_PE2H3 cds-NP_012045.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:448359-448928:+ gene-YHR175W_PE2H4 rna-NM_001179306.3_PE2H4 cds-NP_012045.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:452872-453441:+ gene-YHR175W_S288C rna-NM_001179306.3_S288C cds-NP_012045.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000079.1:690-1259:+ gene-YHR175W_SA1 rna-NM_001179306.3_SA1 cds-NP_012045.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:442044-442613:+ gene-YHR175W_ThermosaccDry rna-NM_001179306.3_ThermosaccDry cds-NP_012045.3_ThermosaccDry 98.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:449858-450427:+ gene-YHR175W_VR1 rna-NM_001179306.3_VR1 cds-NP_012045.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:432285-432854:+ gene-YHR175W_ZTW1 rna-NM_001179306.3_ZTW1 cds-NP_012045.3_ZTW1 98.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:438424-438994:+ gene-YHR175W_Sparadoxus rna-NM_001179306.3_Sparadoxus cds-NP_012045.3_Sparadoxus 90.4 99.4 Unannotated 1 1 0 False False False True False

Additional files