CTK2 (YJL006C)


Gene profile

Gene name: CTK2
Reference locus (S288C): YJL006C
Gene biotype: protein_coding

Description: Beta subunit of C-terminal domain kinase I (CTDK-I); which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; relocalizes to the cytosol in response to hypoxia

Top 10 interactors (score): SGV1 (0.999); CTK1 (0.999); CTK3 (0.999); KIN28 (0.996); SPT5 (0.993); RPO21 (0.993); CCL1 (0.981); TFB3 (0.978); PHO85 (0.977); SSN3 (0.975); CDC28 (0.974); BUR2 (0.959); CKS1 (0.957); PHO80 (0.956); CLB1 (0.948); CLN2 (0.948); SSL2 (0.944); DST1 (0.94); TFB4 (0.933); CDC73 (0.932)

Homologues (species, bitscore): CCNK (Homo sapiens, 67.0); Ccnk (Mus musculus, 66.6); ccnk (Danio rerio, 68.6); ccnk (Xenopus tropicalis, 65.5); CycK (Drosophila melanogaster, 53.5); CYCT1;4 (Arabidopsis thaliana, 51.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:406292-407263:- gene-YJL006C_AKU4011 rna-NM_001181440.1_AKU4011 cds-NP_012528.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:205472-206443:+ gene-YJL006C_BG1 rna-NM_001181440.1_BG1 cds-NP_012528.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:420376-421347:- gene-YJL006C_Bruggeman rna-NM_001181440.1_Bruggeman cds-NP_012528.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:424331-425302:- gene-YJL006C_CAT1 rna-NM_001181440.1_CAT1 cds-NP_012528.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:417879-418850:- gene-YJL006C_CBS1585 rna-NM_001181440.1_CBS1585 cds-NP_012528.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:436842-437813:- gene-YJL006C_CBS436 rna-NM_001181440.1_CBS436 cds-NP_012528.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:406106-407077:- gene-YJL006C_CBS6412 rna-NM_001181440.1_CBS6412 cds-NP_012528.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:408318-409289:- gene-YJL006C_CBS6413 rna-NM_001181440.1_CBS6413 cds-NP_012528.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:405558-406529:- gene-YJL006C_CENPK1137D rna-NM_001181440.1_CENPK1137D cds-NP_012528.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:411254-412225:- gene-YJL006C_EthanolRed rna-NM_001181440.1_EthanolRed cds-NP_012528.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:422398-423369:- gene-YJL006C_FaliES1 rna-NM_001181440.1_FaliES1 cds-NP_012528.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000338.1:497-1468:+ gene-YJL006C_JAY291 rna-NM_001181440.1_JAY291 cds-NP_012528.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:420715-421686:- gene-YJL006C_MUCL30387 rna-NM_001181440.1_MUCL30387 cds-NP_012528.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:417270-418241:- gene-YJL006C_MUCL30388 rna-NM_001181440.1_MUCL30388 cds-NP_012528.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:411196-412167:- gene-YJL006C_MUCL39482 rna-NM_001181440.1_MUCL39482 cds-NP_012528.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:416650-417621:- gene-YJL006C_MUCL42920 rna-NM_001181440.1_MUCL42920 cds-NP_012528.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:423117-424088:- gene-YJL006C_NCIM3186 rna-NM_001181440.1_NCIM3186 cds-NP_012528.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:409109-410080:- gene-YJL006C_NCYC1407 rna-NM_001181440.1_NCYC1407 cds-NP_012528.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:421595-422566:- gene-YJL006C_PE2H3 rna-NM_001181440.1_PE2H3 cds-NP_012528.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:421204-422175:- gene-YJL006C_PE2H4 rna-NM_001181440.1_PE2H4 cds-NP_012528.1_PE2H4 99.5 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:423138-424109:- gene-YJL006C_S288C rna-NM_001181440.1_S288C cds-NP_012528.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:219131-220102:- gene-YJL006C_SA1 rna-NM_001181440.1_SA1 cds-NP_012528.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:416056-417027:- gene-YJL006C_ThermosaccDry rna-NM_001181440.1_ThermosaccDry cds-NP_012528.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:417751-418722:- gene-YJL006C_VR1 rna-NM_001181440.1_VR1 cds-NP_012528.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:396066-397037:- gene-YJL006C_ZTW1 rna-NM_001181440.1_ZTW1 cds-NP_012528.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:420981-421952:- gene-YJL006C_Sparadoxus rna-NM_001181440.1_Sparadoxus cds-NP_012528.1_Sparadoxus 90.0 100.0 Verified 1 1 1 False True False False False

Additional files