CTH1 (YDR151C)


Gene profile

Gene name: CTH1
Reference locus (S288C): YDR151C
Gene biotype: protein_coding

Description: mRNA decay factor CTH1; Member of the CCCH zinc finger family; similar to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis; CTH1 has a paralog, TIS11, that arose from the whole genome duplication

Top 10 interactors (score): CDC39 (0.917); ARI1 (0.893); YDR541C (0.813); GRE2 (0.753); POP2 (0.678); TIS11 (0.656); HEK2 (0.582); PHO92 (0.579); SGN1 (0.572); MTR4 (0.546); MOT2 (0.507); SNU23 (0.481); MGA2 (0.478); IOC2 (0.477); PAP1 (0.471); YTH1 (0.457); DHH1 (0.44); ESS1 (0.428); GDE1 (0.418); PBP2 (0.415)

Homologues (species, bitscore): ZFP36L1 (Homo sapiens, 86.3); Zfp36l3 (Mus musculus, 88.6); sb:cb81 (Danio rerio, 89.4); zfp36l1 (Xenopus tropicalis, 86.7); Tis11 (Drosophila melanogaster, 89.4); ccch-1 (Caenorhabditis elegans, 79.3); AT1G66810 (Arabidopsis thaliana, 67.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:735495-736472:- gene-YDR151C_AKU4011 rna-NM_001180458.1_AKU4011 cds-NP_010435.1_AKU4011 98.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:390279-391256:+ gene-YDR151C_BG1 rna-NM_001180458.1_BG1 cds-NP_010435.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:766992-767969:- gene-YDR151C_Bruggeman rna-NM_001180458.1_Bruggeman cds-NP_010435.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:754282-755259:- gene-YDR151C_CAT1 rna-NM_001180458.1_CAT1 cds-NP_010435.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:725863-726840:- gene-YDR151C_CBS1585 rna-NM_001180458.1_CBS1585 cds-NP_010435.1_CBS1585 98.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:752037-753014:- gene-YDR151C_CBS436 rna-NM_001180458.1_CBS436 cds-NP_010435.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:721349-722326:- gene-YDR151C_CBS6412 rna-NM_001180458.1_CBS6412 cds-NP_010435.1_CBS6412 98.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:749761-750738:- gene-YDR151C_CBS6413 rna-NM_001180458.1_CBS6413 cds-NP_010435.1_CBS6413 98.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:764860-765837:- gene-YDR151C_CENPK1137D rna-NM_001180458.1_CENPK1137D cds-NP_010435.1_CENPK1137D 98.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:735319-736296:- gene-YDR151C_EthanolRed rna-NM_001180458.1_EthanolRed cds-NP_010435.1_EthanolRed 98.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:743531-744508:- gene-YDR151C_FaliES1 rna-NM_001180458.1_FaliES1 cds-NP_010435.1_FaliES1 98.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000401.1:4448-5425:- gene-YDR151C_JAY291 rna-NM_001180458.1_JAY291 cds-NP_010435.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:751963-752940:- gene-YDR151C_MUCL30387 rna-NM_001180458.1_MUCL30387 cds-NP_010435.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:740880-741857:- gene-YDR151C_MUCL30388 rna-NM_001180458.1_MUCL30388 cds-NP_010435.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:727290-728267:- gene-YDR151C_MUCL39482 rna-NM_001180458.1_MUCL39482 cds-NP_010435.1_MUCL39482 98.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:665120-666097:- gene-YDR151C_MUCL42920 rna-NM_001180458.1_MUCL42920 cds-NP_010435.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:764101-765078:- gene-YDR151C_NCIM3186 rna-NM_001180458.1_NCIM3186 cds-NP_010435.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:726695-727672:- gene-YDR151C_NCYC1407 rna-NM_001180458.1_NCYC1407 cds-NP_010435.1_NCYC1407 98.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:745887-746864:- gene-YDR151C_PE2H3 rna-NM_001180458.1_PE2H3 cds-NP_010435.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:745192-746169:- gene-YDR151C_PE2H4 rna-NM_001180458.1_PE2H4 cds-NP_010435.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:764178-765155:- gene-YDR151C_S288C rna-NM_001180458.1_S288C cds-NP_010435.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:111398-112375:- gene-YDR151C_SA1 rna-NM_001180458.1_SA1 cds-NP_010435.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:741666-742643:- gene-YDR151C_ThermosaccDry rna-NM_001180458.1_ThermosaccDry cds-NP_010435.1_ThermosaccDry 98.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:756596-757573:- gene-YDR151C_VR1 rna-NM_001180458.1_VR1 cds-NP_010435.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:4421-5397:- gene-YDR151C_ZTW1 rna-NM_001180458.1_ZTW1 cds-NP_010435.1_ZTW1 99.3 99.8 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:747953-748930:- gene-YDR151C_Sparadoxus rna-NM_001180458.1_Sparadoxus cds-NP_010435.1_Sparadoxus 86.8 99.5 Verified 1 1 1 False True False False False

Additional files