Gene name: CTF19
Reference locus (S288C): YPL018W
Gene biotype: protein_coding
Description: Central kinetochore subunit CTF19; Outer kinetochore protein, needed for accurate chromosome segregation; component of kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as platform for kinetochore assembly; required for spindle assembly checkpoint; minimizes potentially deleterious centromere-proximal crossovers by preventing meiotic DNA break formation proximal to centromere; homolog of human centromere constitutive-associated network (CCAN) subunit CENP-P and fission yeast fta2
Top 10 interactors (score): IML3 (0.999); OKP1 (0.999); MCM21 (0.999); AME1 (0.999); CSE4 (0.999); CHL4 (0.997); CTF3 (0.997); MCM22 (0.995); MCM16 (0.995); NKP2 (0.992); NKP1 (0.986); MTW1 (0.983); DSN1 (0.983); MAD2 (0.951); CBF2 (0.943); DAM1 (0.936); MIF2 (0.935); NDC80 (0.919); HHF1 (0.903); NSL1 (0.898)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:489140-490249:+ | gene-YPL018W_AKU4011 | rna-NM_001183832.1_AKU4011 | cds-NP_015307.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:407095-408204:- | gene-YPL018W_BG1 | rna-NM_001183832.1_BG1 | cds-NP_015307.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:566089-567198:+ | gene-YPL018W_Bruggeman | rna-NM_001183832.1_Bruggeman | cds-NP_015307.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:605753-606862:+ | gene-YPL018W_CAT1 | rna-NM_001183832.1_CAT1 | cds-NP_015307.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:493212-494321:+ | gene-YPL018W_CBS1585 | rna-NM_001183832.1_CBS1585 | cds-NP_015307.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:507339-508448:+ | gene-YPL018W_CBS436 | rna-NM_001183832.1_CBS436 | cds-NP_015307.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:497403-498512:+ | gene-YPL018W_CBS6412 | rna-NM_001183832.1_CBS6412 | cds-NP_015307.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:489765-490874:+ | gene-YPL018W_CBS6413 | rna-NM_001183832.1_CBS6413 | cds-NP_015307.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:517612-518721:+ | gene-YPL018W_CENPK1137D | rna-NM_001183832.1_CENPK1137D | cds-NP_015307.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:487504-488613:+ | gene-YPL018W_EthanolRed | rna-NM_001183832.1_EthanolRed | cds-NP_015307.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:495334-496443:+ | gene-YPL018W_FaliES1 | rna-NM_001183832.1_FaliES1 | cds-NP_015307.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000283.1:103935-105045:+ | gene-YPL018W_JAY291 | rna-NM_001183832.1_JAY291 | cds-NP_015307.1_JAY291 | 99.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:507037-508146:+ | gene-YPL018W_MUCL30387 | rna-NM_001183832.1_MUCL30387 | cds-NP_015307.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:506145-507254:+ | gene-YPL018W_MUCL30388 | rna-NM_001183832.1_MUCL30388 | cds-NP_015307.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:486530-487639:+ | gene-YPL018W_MUCL39482 | rna-NM_001183832.1_MUCL39482 | cds-NP_015307.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:545657-546766:+ | gene-YPL018W_MUCL42920 | rna-NM_001183832.1_MUCL42920 | cds-NP_015307.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:517634-518743:+ | gene-YPL018W_NCIM3186 | rna-NM_001183832.1_NCIM3186 | cds-NP_015307.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:493807-494916:+ | gene-YPL018W_NCYC1407 | rna-NM_001183832.1_NCYC1407 | cds-NP_015307.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:500463-501572:+ | gene-YPL018W_PE2H3 | rna-NM_001183832.1_PE2H3 | cds-NP_015307.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:500078-501187:+ | gene-YPL018W_PE2H4 | rna-NM_001183832.1_PE2H4 | cds-NP_015307.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:517651-518760:+ | gene-YPL018W_S288C | rna-NM_001183832.1_S288C | cds-NP_015307.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000076.1:14328-15437:+ | gene-YPL018W_SA1 | rna-NM_001183832.1_SA1 | cds-NP_015307.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:495133-496242:+ | gene-YPL018W_ThermosaccDry | rna-NM_001183832.1_ThermosaccDry | cds-NP_015307.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:510269-511378:+ | gene-YPL018W_VR1 | rna-NM_001183832.1_VR1 | cds-NP_015307.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:494419-495528:+ | gene-YPL018W_ZTW1 | rna-NM_001183832.1_ZTW1 | cds-NP_015307.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:494375-495487:+ | gene-YPL018W_Sparadoxus | rna-NM_001183832.1_Sparadoxus | cds-NP_015307.1_Sparadoxus | 88.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |