Gene name: CSL4
Reference locus (S288C): YNL232W
Gene biotype: protein_coding
Description: Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain an S1 RNA binding domain; human homolog EXOSC1 partially complements yeast csl4 null mutant, and can complement inviability of strain in which expression of CSL4 is repressed
Top 10 interactors (score): DIS3 (0.999); RRP4 (0.999); RRP46 (0.999); MTR3 (0.999); SKI7 (0.999); RRP42 (0.999); MPP6 (0.999); RRP45 (0.999); MTR4 (0.999); SKI6 (0.999); RRP40 (0.999); LRP1 (0.999); RRP43 (0.999); RRP6 (0.999); SKI2 (0.994); IMP4 (0.99); SKI3 (0.987); SKI8 (0.985); DSS1 (0.979); NOP1 (0.975)
Homologues (species, bitscore): EXOSC1 (Homo sapiens, 90.5); Exosc1 (Mus musculus, 90.5); exosc1 (Danio rerio, 90.9); exosc1 (Xenopus tropicalis, 93.6); Csl4 (Drosophila melanogaster, 71.6); AT5G38890 (Arabidopsis thaliana, 107.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:208705-209583:+ | gene-YNL232W_AKU4011 | rna-NM_001183070.1_AKU4011 | cds-NP_014167.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:112650-113528:+ | gene-YNL232W_BG1 | rna-NM_001183070.1_BG1 | cds-NP_014167.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:218756-219634:+ | gene-YNL232W_Bruggeman | rna-NM_001183070.1_Bruggeman | cds-NP_014167.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:225908-226786:+ | gene-YNL232W_CAT1 | rna-NM_001183070.1_CAT1 | cds-NP_014167.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:209102-209980:+ | gene-YNL232W_CBS1585 | rna-NM_001183070.1_CBS1585 | cds-NP_014167.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:204188-205066:+ | gene-YNL232W_CBS436 | rna-NM_001183070.1_CBS436 | cds-NP_014167.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:205136-206014:+ | gene-YNL232W_CBS6412 | rna-NM_001183070.1_CBS6412 | cds-NP_014167.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:205784-206662:+ | gene-YNL232W_CBS6413 | rna-NM_001183070.1_CBS6413 | cds-NP_014167.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:208734-209612:+ | gene-YNL232W_CENPK1137D | rna-NM_001183070.1_CENPK1137D | cds-NP_014167.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:206355-207233:+ | gene-YNL232W_EthanolRed | rna-NM_001183070.1_EthanolRed | cds-NP_014167.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:201097-201975:+ | gene-YNL232W_FaliES1 | rna-NM_001183070.1_FaliES1 | cds-NP_014167.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:112238-113116:+ | gene-YNL232W_JAY291 | rna-NM_001183070.1_JAY291 | cds-NP_014167.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:214290-215168:+ | gene-YNL232W_MUCL30387 | rna-NM_001183070.1_MUCL30387 | cds-NP_014167.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:212875-213753:+ | gene-YNL232W_MUCL30388 | rna-NM_001183070.1_MUCL30388 | cds-NP_014167.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:206592-207470:+ | gene-YNL232W_MUCL39482 | rna-NM_001183070.1_MUCL39482 | cds-NP_014167.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:208847-209725:+ | gene-YNL232W_MUCL42920 | rna-NM_001183070.1_MUCL42920 | cds-NP_014167.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:214892-215770:+ | gene-YNL232W_NCIM3186 | rna-NM_001183070.1_NCIM3186 | cds-NP_014167.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:208683-209561:+ | gene-YNL232W_NCYC1407 | rna-NM_001183070.1_NCYC1407 | cds-NP_014167.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:205581-206459:+ | gene-YNL232W_PE2H3 | rna-NM_001183070.1_PE2H3 | cds-NP_014167.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:204969-205847:+ | gene-YNL232W_PE2H4 | rna-NM_001183070.1_PE2H4 | cds-NP_014167.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:214923-215801:+ | gene-YNL232W_S288C | rna-NM_001183070.1_S288C | cds-NP_014167.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:36499-37377:- | gene-YNL232W_SA1 | rna-NM_001183070.1_SA1 | cds-NP_014167.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:201953-202831:+ | gene-YNL232W_ThermosaccDry | rna-NM_001183070.1_ThermosaccDry | cds-NP_014167.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:220941-221819:+ | gene-YNL232W_VR1 | rna-NM_001183070.1_VR1 | cds-NP_014167.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:112271-113149:+ | gene-YNL232W_ZTW1 | rna-NM_001183070.1_ZTW1 | cds-NP_014167.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:212312-213190:+ | gene-YNL232W_Sparadoxus | rna-NM_001183070.1_Sparadoxus | cds-NP_014167.1_Sparadoxus | 89.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |