Gene name: CSE1
Reference locus (S288C): YGL238W
Gene biotype: protein_coding
Description: Importin alpha re-exporter; Nuclear envelope protein that acts as a recycling factor; mediates the nuclear export of Srp1p (importin alpha) back to the cytoplasm after its import substrates have been released into the nucleoplasm, thereby allowing the participation of Srp1p in multiple rounds of nuclear import; required for accurate chromosome segregation; homolog of metazoan CAS and human CSE1L, overexpression of which is implicated in cancer progression
Top 10 interactors (score): GSP1 (0.999); KAP95 (0.999); SRP1 (0.999); KAP123 (0.997); PSE1 (0.996); GSP2 (0.986); CRM1 (0.986); LOS1 (0.974); NUP2 (0.958); KAP104 (0.937); MSN5 (0.935); MTR10 (0.913); NUP170 (0.912); NTF2 (0.905); SNU114 (0.892); RFC2 (0.892); NUP157 (0.887); UBA2 (0.879); KAP114 (0.843); NUP84 (0.833)
Homologues (species, bitscore): CSE1L (Homo sapiens, 590.1); Cse1l (Mus musculus, 595.1); cse1l (Danio rerio, 571.2); cse1l (Xenopus tropicalis, 584.7); Cas (Drosophila melanogaster, 539.7); xpo-2 (Caenorhabditis elegans, 316.6); AT2G46520 (Arabidopsis thaliana, 455.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:51084-53966:+ | gene-YGL238W_AKU4011 | rna-NM_001181104.1_AKU4011 | cds-NP_011276.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000175.1:43116-45998:+ | gene-YGL238W_BG1 | rna-NM_001181104.1_BG1 | cds-NP_011276.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:51431-54313:+ | gene-YGL238W_Bruggeman | rna-NM_001181104.1_Bruggeman | cds-NP_011276.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:49503-52385:+ | gene-YGL238W_CAT1 | rna-NM_001181104.1_CAT1 | cds-NP_011276.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:55372-58254:+ | gene-YGL238W_CBS1585 | rna-NM_001181104.1_CBS1585 | cds-NP_011276.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:50093-52975:+ | gene-YGL238W_CBS436 | rna-NM_001181104.1_CBS436 | cds-NP_011276.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:42941-45823:+ | gene-YGL238W_CBS6412 | rna-NM_001181104.1_CBS6412 | cds-NP_011276.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:49229-52111:+ | gene-YGL238W_CBS6413 | rna-NM_001181104.1_CBS6413 | cds-NP_011276.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:49212-52094:+ | gene-YGL238W_CENPK1137D | rna-NM_001181104.1_CENPK1137D | cds-NP_011276.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:42172-45054:+ | gene-YGL238W_EthanolRed | rna-NM_001181104.1_EthanolRed | cds-NP_011276.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:42757-45639:+ | gene-YGL238W_FaliES1 | rna-NM_001181104.1_FaliES1 | cds-NP_011276.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000079.1:21485-24367:- | gene-YGL238W_JAY291 | rna-NM_001181104.1_JAY291 | cds-NP_011276.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:51369-54251:+ | gene-YGL238W_MUCL30387 | rna-NM_001181104.1_MUCL30387 | cds-NP_011276.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:53521-56403:+ | gene-YGL238W_MUCL30388 | rna-NM_001181104.1_MUCL30388 | cds-NP_011276.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:51969-54851:+ | gene-YGL238W_MUCL39482 | rna-NM_001181104.1_MUCL39482 | cds-NP_011276.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:54854-57736:+ | gene-YGL238W_MUCL42920 | rna-NM_001181104.1_MUCL42920 | cds-NP_011276.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:49552-52434:+ | gene-YGL238W_NCIM3186 | rna-NM_001181104.1_NCIM3186 | cds-NP_011276.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:43729-46611:+ | gene-YGL238W_NCYC1407 | rna-NM_001181104.1_NCYC1407 | cds-NP_011276.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:45582-48464:+ | gene-YGL238W_PE2H3 | rna-NM_001181104.1_PE2H3 | cds-NP_011276.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:45130-48012:+ | gene-YGL238W_PE2H4 | rna-NM_001181104.1_PE2H4 | cds-NP_011276.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:49552-52434:+ | gene-YGL238W_S288C | rna-NM_001181104.1_S288C | cds-NP_011276.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:322900-325782:- | gene-YGL238W_SA1 | rna-NM_001181104.1_SA1 | cds-NP_011276.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:43063-45945:+ | gene-YGL238W_ThermosaccDry | rna-NM_001181104.1_ThermosaccDry | cds-NP_011276.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:50018-52900:+ | gene-YGL238W_VR1 | rna-NM_001181104.1_VR1 | cds-NP_011276.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:42108-44990:+ | gene-YGL238W_ZTW1 | rna-NM_001181104.1_ZTW1 | cds-NP_011276.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:50800-53682:+ | gene-YGL238W_Sparadoxus | rna-NM_001181104.1_Sparadoxus | cds-NP_011276.1_Sparadoxus | 92.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |