CRS1 (YNL247W)


Gene profile

Gene name: CRS1
Reference locus (S288C): YNL247W
Gene biotype: protein_coding

Description: Cysteine--tRNA ligase; Cysteinyl-tRNA synthetase; may interact with ribosomes, based on co-purification experiments; human gene CARS allows growth of the yeast haploid null mutant after sporulation of a heterozygous diploid

Top 10 interactors (score): SES1 (0.993); ILS1 (0.989); TEF4 (0.985); TYS1 (0.984); CDC60 (0.984); DIA4 (0.983); CAM1 (0.981); ISM1 (0.958); ALA1 (0.946); GLN4 (0.945); NAM2 (0.915); YDR341C (0.908); VAS1 (0.906); MES1 (0.902); LIA1 (0.891); MSD1 (0.89); MSY1 (0.884); THS1 (0.877); YHR020W (0.871); GRS1 (0.866)

Homologues (species, bitscore): CARS (Homo sapiens, 615.9); Cars (Mus musculus, 619.8); cars (Danio rerio, 633.3); cars1 (Xenopus tropicalis, 517.3); Aats-cys (Drosophila melanogaster, 599.7); cars-1 (Caenorhabditis elegans, 560.1); SYCO (Arabidopsis thaliana, 251.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:176660-178963:+ gene-YNL247W_AKU4011 rna-NM_001183085.1_AKU4011 cds-NP_014152.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:80604-82907:+ gene-YNL247W_BG1 rna-NM_001183085.1_BG1 cds-NP_014152.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:186467-188770:+ gene-YNL247W_Bruggeman rna-NM_001183085.1_Bruggeman cds-NP_014152.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:193762-196065:+ gene-YNL247W_CAT1 rna-NM_001183085.1_CAT1 cds-NP_014152.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:177057-179360:+ gene-YNL247W_CBS1585 rna-NM_001183085.1_CBS1585 cds-NP_014152.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:172147-174450:+ gene-YNL247W_CBS436 rna-NM_001183085.1_CBS436 cds-NP_014152.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:173471-175706:+ gene-YNL247W_CBS6412 rna-NM_001183085.1_CBS6412 cds-NP_014152.1_CBS6412 90.6 95.3 Unannotated 1 1 0 False False False True False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:173739-176042:+ gene-YNL247W_CBS6413 rna-NM_001183085.1_CBS6413 cds-NP_014152.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:176686-178989:+ gene-YNL247W_CENPK1137D rna-NM_001183085.1_CENPK1137D cds-NP_014152.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:174317-176620:+ gene-YNL247W_EthanolRed rna-NM_001183085.1_EthanolRed cds-NP_014152.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:169052-171355:+ gene-YNL247W_FaliES1 rna-NM_001183085.1_FaliES1 cds-NP_014152.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000082.1:80197-82500:+ gene-YNL247W_JAY291 rna-NM_001183085.1_JAY291 cds-NP_014152.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:182250-184553:+ gene-YNL247W_MUCL30387 rna-NM_001183085.1_MUCL30387 cds-NP_014152.1_MUCL30387 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:180833-183136:+ gene-YNL247W_MUCL30388 rna-NM_001183085.1_MUCL30388 cds-NP_014152.1_MUCL30388 99.3 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:174547-176850:+ gene-YNL247W_MUCL39482 rna-NM_001183085.1_MUCL39482 cds-NP_014152.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:176806-179109:+ gene-YNL247W_MUCL42920 rna-NM_001183085.1_MUCL42920 cds-NP_014152.1_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:182844-185147:+ gene-YNL247W_NCIM3186 rna-NM_001183085.1_NCIM3186 cds-NP_014152.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:176639-178942:+ gene-YNL247W_NCYC1407 rna-NM_001183085.1_NCYC1407 cds-NP_014152.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:173540-175843:+ gene-YNL247W_PE2H3 rna-NM_001183085.1_PE2H3 cds-NP_014152.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:172928-175231:+ gene-YNL247W_PE2H4 rna-NM_001183085.1_PE2H4 cds-NP_014152.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:182875-185178:+ gene-YNL247W_S288C rna-NM_001183085.1_S288C cds-NP_014152.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000040.1:67115-69418:- gene-YNL247W_SA1 rna-NM_001183085.1_SA1 cds-NP_014152.1_SA1 99.3 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:169908-172211:+ gene-YNL247W_ThermosaccDry rna-NM_001183085.1_ThermosaccDry cds-NP_014152.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:188797-191100:+ gene-YNL247W_VR1 rna-NM_001183085.1_VR1 cds-NP_014152.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:80230-82533:+ gene-YNL247W_ZTW1 rna-NM_001183085.1_ZTW1 cds-NP_014152.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:180174-182474:+ gene-YNL247W_Sparadoxus rna-NM_001183085.1_Sparadoxus cds-NP_014152.1_Sparadoxus 91.0 99.8 Verified 1 1 1 False True False False False

Additional files