Gene name: CRD1
Reference locus (S288C): YDL142C
Gene biotype: protein_coding
Description: Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function and for correct integration of membrane-multispanning proteins into the mitochondrial outer membrane; required to maintain tubular mitochondrial morphology and functions in mitochondrial fusion; also required for normal vacuolar ion homeostasis; Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Top 10 interactors (score): PGS1 (0.996); GEP4 (0.994); TAZ1 (0.994); CDS1 (0.988); PSD1 (0.979); PIS1 (0.976); CHO1 (0.976); CLD1 (0.975); ALE1 (0.969); TAM41 (0.962); PGC1 (0.918); UPS1 (0.906); UPS2 (0.869); MDM35 (0.832); PDS5 (0.811); YKR070W (0.802); FMP30 (0.801); PSD2 (0.792); SPO14 (0.748); CYB2 (0.728)
Homologues (species, bitscore): CRLS1 (Homo sapiens, 100.5); Crls1 (Mus musculus, 94.7); crls1 (Danio rerio, 100.1); crls1 (Xenopus tropicalis, 98.2); CLS (Drosophila melanogaster, 99.8); crls-1 (Caenorhabditis elegans, 99.4); CLS (Arabidopsis thaliana, 88.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:186136-186987:- | gene-YDL142C_AKU4011 | rna-NM_001180202.1_AKU4011 | cds-NP_010139.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:362791-363642:+ | gene-YDL142C_BG1 | rna-NM_001180202.1_BG1 | cds-NP_010139.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:202179-203030:- | gene-YDL142C_Bruggeman | rna-NM_001180202.1_Bruggeman | cds-NP_010139.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:200501-201352:- | gene-YDL142C_CAT1 | rna-NM_001180202.1_CAT1 | cds-NP_010139.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:184167-185018:- | gene-YDL142C_CBS1585 | rna-NM_001180202.1_CBS1585 | cds-NP_010139.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:201105-201956:- | gene-YDL142C_CBS436 | rna-NM_001180202.1_CBS436 | cds-NP_010139.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:183420-184271:- | gene-YDL142C_CBS6412 | rna-NM_001180202.1_CBS6412 | cds-NP_010139.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:202605-203456:- | gene-YDL142C_CBS6413 | rna-NM_001180202.1_CBS6413 | cds-NP_010139.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:200371-201222:- | gene-YDL142C_CENPK1137D | rna-NM_001180202.1_CENPK1137D | cds-NP_010139.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:197375-198226:- | gene-YDL142C_EthanolRed | rna-NM_001180202.1_EthanolRed | cds-NP_010139.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:202907-203758:- | gene-YDL142C_FaliES1 | rna-NM_001180202.1_FaliES1 | cds-NP_010139.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:15792-16643:+ | gene-YDL142C_JAY291 | rna-NM_001180202.1_JAY291 | cds-NP_010139.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:201293-202144:- | gene-YDL142C_MUCL30387 | rna-NM_001180202.1_MUCL30387 | cds-NP_010139.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:192153-193004:- | gene-YDL142C_MUCL30388 | rna-NM_001180202.1_MUCL30388 | cds-NP_010139.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:185322-186173:- | gene-YDL142C_MUCL39482 | rna-NM_001180202.1_MUCL39482 | cds-NP_010139.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000205.1:15747-16598:+ | gene-YDL142C_MUCL42920 | rna-NM_001180202.1_MUCL42920 | cds-NP_010139.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:201642-202493:- | gene-YDL142C_NCIM3186 | rna-NM_001180202.1_NCIM3186 | cds-NP_010139.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:185256-186107:- | gene-YDL142C_NCYC1407 | rna-NM_001180202.1_NCYC1407 | cds-NP_010139.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:192498-193349:- | gene-YDL142C_PE2H3 | rna-NM_001180202.1_PE2H3 | cds-NP_010139.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:192502-193353:- | gene-YDL142C_PE2H4 | rna-NM_001180202.1_PE2H4 | cds-NP_010139.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:201719-202570:- | gene-YDL142C_S288C | rna-NM_001180202.1_S288C | cds-NP_010139.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:67276-68127:- | gene-YDL142C_SA1 | rna-NM_001180202.1_SA1 | cds-NP_010139.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:202668-203519:- | gene-YDL142C_ThermosaccDry | rna-NM_001180202.1_ThermosaccDry | cds-NP_010139.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:203262-204113:- | gene-YDL142C_VR1 | rna-NM_001180202.1_VR1 | cds-NP_010139.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:200794-201645:- | gene-YDL142C_ZTW1 | rna-NM_001180202.1_ZTW1 | cds-NP_010139.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:202925-203776:- | gene-YDL142C_Sparadoxus | rna-NM_001180202.1_Sparadoxus | cds-NP_010139.1_Sparadoxus | 87.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |