Gene name: CPR6
Reference locus (S288C): YLR216C
Gene biotype: protein_coding
Description: Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; plays a role in determining prion variants; binds to Hsp82p and contributes to chaperone activity; protein abundance increases in response to DNA replication stress; Belongs to the cyclophilin-type PPIase family. PPIase D subfamily
Top 10 interactors (score): SBA1 (0.999); AHA1 (0.999); STI1 (0.999); HSC82 (0.999); HSP82 (0.999); HSP104 (0.995); HSP78 (0.992); SIS1 (0.991); CNS1 (0.983); FES1 (0.978); HCH1 (0.97); MBF1 (0.94); HSP26 (0.938); SGT2 (0.911); CDC37 (0.908); YDJ1 (0.906); SSE1 (0.903); SHP1 (0.896); SSA2 (0.887); SSA1 (0.886)
Homologues (species, bitscore): PPID (Homo sapiens, 299.7); Ppid (Mus musculus, 302.8); ppid (Danio rerio, 220.7); ppid (Xenopus tropicalis, 304.7); Moca-cyp (Drosophila melanogaster, 222.6); cyn-3 (Caenorhabditis elegans, 209.9); SQN (Arabidopsis thaliana, 281.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:526239-527354:- | gene-YLR216C_AKU4011 | rna-NM_001182103.1_AKU4011 | cds-NP_013317.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:83495-84610:- | gene-YLR216C_BG1 | rna-NM_001182103.1_BG1 | cds-NP_013317.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:566464-567579:- | gene-YLR216C_Bruggeman | rna-NM_001182103.1_Bruggeman | cds-NP_013317.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:566113-567228:- | gene-YLR216C_CAT1 | rna-NM_001182103.1_CAT1 | cds-NP_013317.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:561731-562846:- | gene-YLR216C_CBS1585 | rna-NM_001182103.1_CBS1585 | cds-NP_013317.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:551931-553046:- | gene-YLR216C_CBS436 | rna-NM_001182103.1_CBS436 | cds-NP_013317.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:530293-531408:- | gene-YLR216C_CBS6412 | rna-NM_001182103.1_CBS6412 | cds-NP_013317.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:562028-563143:- | gene-YLR216C_CBS6413 | rna-NM_001182103.1_CBS6413 | cds-NP_013317.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:556819-557934:- | gene-YLR216C_CENPK1137D | rna-NM_001182103.1_CENPK1137D | cds-NP_013317.1_CENPK1137D | 95.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:525751-526866:- | gene-YLR216C_EthanolRed | rna-NM_001182103.1_EthanolRed | cds-NP_013317.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:554678-555793:- | gene-YLR216C_FaliES1 | rna-NM_001182103.1_FaliES1 | cds-NP_013317.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:81581-82696:- | gene-YLR216C_JAY291 | rna-NM_001182103.1_JAY291 | cds-NP_013317.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:567325-568440:- | gene-YLR216C_MUCL30387 | rna-NM_001182103.1_MUCL30387 | cds-NP_013317.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:571446-572561:- | gene-YLR216C_MUCL30388 | rna-NM_001182103.1_MUCL30388 | cds-NP_013317.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:562714-563829:- | gene-YLR216C_MUCL39482 | rna-NM_001182103.1_MUCL39482 | cds-NP_013317.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:563212-564327:- | gene-YLR216C_MUCL42920 | rna-NM_001182103.1_MUCL42920 | cds-NP_013317.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:572070-573185:- | gene-YLR216C_NCIM3186 | rna-NM_001182103.1_NCIM3186 | cds-NP_013317.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:555133-556248:- | gene-YLR216C_NCYC1407 | rna-NM_001182103.1_NCYC1407 | cds-NP_013317.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:559384-560499:- | gene-YLR216C_PE2H3 | rna-NM_001182103.1_PE2H3 | cds-NP_013317.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:559128-560243:- | gene-YLR216C_PE2H4 | rna-NM_001182103.1_PE2H4 | cds-NP_013317.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:572096-573211:- | gene-YLR216C_S288C | rna-NM_001182103.1_S288C | cds-NP_013317.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:81632-82747:- | gene-YLR216C_SA1 | rna-NM_001182103.1_SA1 | cds-NP_013317.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:557171-558286:- | gene-YLR216C_ThermosaccDry | rna-NM_001182103.1_ThermosaccDry | cds-NP_013317.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:568518-569633:- | gene-YLR216C_VR1 | rna-NM_001182103.1_VR1 | cds-NP_013317.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:81459-82574:- | gene-YLR216C_ZTW1 | rna-NM_001182103.1_ZTW1 | cds-NP_013317.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:543319-544434:- | gene-YLR216C_Sparadoxus | rna-NM_001182103.1_Sparadoxus | cds-NP_013317.1_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |