CPR5 (YDR304C)


Gene profile

Gene name: CPR5
Reference locus (S288C): YDR304C
Gene biotype: protein_coding

Description: Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the ER; catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER; CPR5 has a paralog, CPR2, that arose from the whole genome duplication

Top 10 interactors (score): PDI1 (0.981); POR1 (0.945); FPR2 (0.907); KAR2 (0.896); ATP5 (0.809); GUK1 (0.765); HSP82 (0.758); HAM1 (0.741); DUG1 (0.731); FPR1 (0.716); MCX1 (0.705); SUP35 (0.684); LIA1 (0.683); VMA2 (0.678); CNE1 (0.667); ERV25 (0.667); ETR1 (0.655); BXI1 (0.655); HSC82 (0.646); RPP0 (0.644)

Homologues (species, bitscore): PPIB (Homo sapiens, 216.5); Ppib (Mus musculus, 219.9); ppib (Danio rerio, 219.2); ppib (Xenopus tropicalis, 213.4); CG2852 (Drosophila melanogaster, 206.5); cyn-5 (Caenorhabditis elegans, 201.4); ROC7 (Arabidopsis thaliana, 203.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1023893-1024570:- gene-YDR304C_AKU4011 rna-NM_001180612.3_AKU4011 cds-NP_010590.3_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:107006-107683:+ gene-YDR304C_BG1 rna-NM_001180612.3_BG1 cds-NP_010590.3_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1051160-1051837:- gene-YDR304C_Bruggeman rna-NM_001180612.3_Bruggeman cds-NP_010590.3_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1038157-1038834:- gene-YDR304C_CAT1 rna-NM_001180612.3_CAT1 cds-NP_010590.3_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1018338-1019015:- gene-YDR304C_CBS1585 rna-NM_001180612.3_CBS1585 cds-NP_010590.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1036708-1037385:- gene-YDR304C_CBS436 rna-NM_001180612.3_CBS436 cds-NP_010590.3_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1015020-1015697:- gene-YDR304C_CBS6412 rna-NM_001180612.3_CBS6412 cds-NP_010590.3_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1036258-1036935:- gene-YDR304C_CBS6413 rna-NM_001180612.3_CBS6413 cds-NP_010590.3_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1070522-1071199:- gene-YDR304C_CENPK1137D rna-NM_001180612.3_CENPK1137D cds-NP_010590.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1022248-1022925:- gene-YDR304C_EthanolRed rna-NM_001180612.3_EthanolRed cds-NP_010590.3_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1030650-1031327:- gene-YDR304C_FaliES1 rna-NM_001180612.3_FaliES1 cds-NP_010590.3_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000130.1:48442-49119:- gene-YDR304C_JAY291 rna-NM_001180612.3_JAY291 cds-NP_010590.3_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1036645-1037322:- gene-YDR304C_MUCL30387 rna-NM_001180612.3_MUCL30387 cds-NP_010590.3_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1023742-1024419:- gene-YDR304C_MUCL30388 rna-NM_001180612.3_MUCL30388 cds-NP_010590.3_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1010144-1010821:- gene-YDR304C_MUCL39482 rna-NM_001180612.3_MUCL39482 cds-NP_010590.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:950110-950787:- gene-YDR304C_MUCL42920 rna-NM_001180612.3_MUCL42920 cds-NP_010590.3_MUCL42920 99.8 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1071803-1072480:- gene-YDR304C_NCIM3186 rna-NM_001180612.3_NCIM3186 cds-NP_010590.3_NCIM3186 99.5 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1023437-1024114:- gene-YDR304C_NCYC1407 rna-NM_001180612.3_NCYC1407 cds-NP_010590.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1034415-1035092:- gene-YDR304C_PE2H3 rna-NM_001180612.3_PE2H3 cds-NP_010590.3_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1040000-1040677:- gene-YDR304C_PE2H4 rna-NM_001180612.3_PE2H4 cds-NP_010590.3_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1071880-1072557:- gene-YDR304C_S288C rna-NM_001180612.3_S288C cds-NP_010590.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000025.1:48615-49292:- gene-YDR304C_SA1 rna-NM_001180612.3_SA1 cds-NP_010590.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1034923-1035600:- gene-YDR304C_ThermosaccDry rna-NM_001180612.3_ThermosaccDry cds-NP_010590.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1050834-1051511:- gene-YDR304C_VR1 rna-NM_001180612.3_VR1 cds-NP_010590.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:79038-79715:- gene-YDR304C_ZTW1 rna-NM_001180612.3_ZTW1 cds-NP_010590.3_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1030475-1031152:- gene-YDR304C_Sparadoxus rna-NM_001180612.3_Sparadoxus cds-NP_010590.3_Sparadoxus 89.8 100.0 Verified 1 1 1 False True False False False

Additional files