Gene name: CPR2
Reference locus (S288C): YHR057C
Gene biotype: protein_coding
Description: Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; potential role in the secretory pathway; seamless-GFP and mCherry fusion proteins localize to the vacuole, while SWAT-GFP fusion localizes to both the endoplasmic reticulum and vacuole; suppresses toxicity of slow-folding human Z-type alpha1-antitrypsin variant associated with liver cirrhosis and emphysema
Top 10 interactors (score): PDI1 (0.959); FPR2 (0.914); FPR1 (0.902); KAR2 (0.881); CNE1 (0.788); GUK1 (0.684); GPB1 (0.671); SUP35 (0.662); ERV25 (0.662); ETR1 (0.655); NSP1 (0.648); RPP0 (0.643); GPA1 (0.627); STE3 (0.622); HAM1 (0.621); STE2 (0.62); GPA2 (0.594); DUG1 (0.558); LIA1 (0.556); VPS4 (0.549)
Homologues (species, bitscore): PPIB (Homo sapiens, 195.3); Ppib (Mus musculus, 193.0); ppib (Danio rerio, 199.5); ppib (Xenopus tropicalis, 197.2); CG2852 (Drosophila melanogaster, 200.3); cyn-6 (Caenorhabditis elegans, 200.3); ROC4 (Arabidopsis thaliana, 189.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:204485-205102:- | gene-YHR057C_AKU4011 | rna-NM_001179187.1_AKU4011 | cds-NP_011924.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:125625-126242:- | gene-YHR057C_BG1 | rna-NM_001179187.1_BG1 | cds-NP_011924.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:212243-212860:- | gene-YHR057C_Bruggeman | rna-NM_001179187.1_Bruggeman | cds-NP_011924.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:207031-207648:- | gene-YHR057C_CAT1 | rna-NM_001179187.1_CAT1 | cds-NP_011924.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:203591-204208:- | gene-YHR057C_CBS1585 | rna-NM_001179187.1_CBS1585 | cds-NP_011924.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:201548-202165:- | gene-YHR057C_CBS436 | rna-NM_001179187.1_CBS436 | cds-NP_011924.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:203823-204440:- | gene-YHR057C_CBS6412 | rna-NM_001179187.1_CBS6412 | cds-NP_011924.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:204655-205272:- | gene-YHR057C_CBS6413 | rna-NM_001179187.1_CBS6413 | cds-NP_011924.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:211389-212006:- | gene-YHR057C_CENPK1137D | rna-NM_001179187.1_CENPK1137D | cds-NP_011924.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:203982-204599:- | gene-YHR057C_EthanolRed | rna-NM_001179187.1_EthanolRed | cds-NP_011924.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:204959-205576:- | gene-YHR057C_FaliES1 | rna-NM_001179187.1_FaliES1 | cds-NP_011924.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000280.1:11732-12349:+ | gene-YHR057C_JAY291 | rna-NM_001179187.1_JAY291 | cds-NP_011924.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:211698-212315:- | gene-YHR057C_MUCL30387 | rna-NM_001179187.1_MUCL30387 | cds-NP_011924.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:211877-212494:- | gene-YHR057C_MUCL30388 | rna-NM_001179187.1_MUCL30388 | cds-NP_011924.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:203876-204493:- | gene-YHR057C_MUCL39482 | rna-NM_001179187.1_MUCL39482 | cds-NP_011924.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:210782-211399:- | gene-YHR057C_MUCL42920 | rna-NM_001179187.1_MUCL42920 | cds-NP_011924.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:218108-218725:- | gene-YHR057C_NCIM3186 | rna-NM_001179187.1_NCIM3186 | cds-NP_011924.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:675517-676134:- | gene-YHR057C_NCYC1407 | rna-NM_001179187.1_NCYC1407 | cds-NP_011924.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:206079-206696:- | gene-YHR057C_PE2H3 | rna-NM_001179187.1_PE2H3 | cds-NP_011924.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:213526-214143:- | gene-YHR057C_PE2H4 | rna-NM_001179187.1_PE2H4 | cds-NP_011924.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:218226-218843:- | gene-YHR057C_S288C | rna-NM_001179187.1_S288C | cds-NP_011924.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:140598-141215:+ | gene-YHR057C_SA1 | rna-NM_001179187.1_SA1 | cds-NP_011924.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:206050-206667:- | gene-YHR057C_ThermosaccDry | rna-NM_001179187.1_ThermosaccDry | cds-NP_011924.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:213689-214306:- | gene-YHR057C_VR1 | rna-NM_001179187.1_VR1 | cds-NP_011924.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:197603-198220:- | gene-YHR057C_ZTW1 | rna-NM_001179187.1_ZTW1 | cds-NP_011924.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:203137-203754:- | gene-YHR057C_Sparadoxus | rna-NM_001179187.1_Sparadoxus | cds-NP_011924.1_Sparadoxus | 89.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |