CPR1 (YDR155C)


Gene profile

Gene name: CPR1
Reference locus (S288C): YDR155C
Gene biotype: protein_coding

Description: Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A; N-terminally propionylated in vivo; protein abundance increases in response to DNA replication stress; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily

Top 10 interactors (score): SIF2 (0.999); SNT1 (0.998); FPR1 (0.998); HOS4 (0.998); SET3 (0.997); HOS2 (0.996); NSP1 (0.971); SEC4 (0.964); HSC82 (0.937); HST1 (0.936); NUP2 (0.934); YNK1 (0.922); HSP82 (0.916); FPR2 (0.902); EFG1 (0.898); UBC9 (0.872); ESS1 (0.871); RNA1 (0.866); SUM1 (0.856); NDT80 (0.856)

Homologues (species, bitscore): PPIF (Homo sapiens, 236.5); Ppif (Mus musculus, 237.7); ppifb (Danio rerio, 235.0); ppia (Xenopus tropicalis, 229.2); Cyp1 (Drosophila melanogaster, 245.7); cyn-7 (Caenorhabditis elegans, 231.5); ROC1 (Arabidopsis thaliana, 225.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:739834-740322:- gene-YDR155C_AKU4011 rna-NM_001180462.1_AKU4011 cds-NP_010439.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:386433-386921:+ gene-YDR155C_BG1 rna-NM_001180462.1_BG1 cds-NP_010439.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:771331-771819:- gene-YDR155C_Bruggeman rna-NM_001180462.1_Bruggeman cds-NP_010439.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:758619-759107:- gene-YDR155C_CAT1 rna-NM_001180462.1_CAT1 cds-NP_010439.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:730202-730690:- gene-YDR155C_CBS1585 rna-NM_001180462.1_CBS1585 cds-NP_010439.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:756371-756859:- gene-YDR155C_CBS436 rna-NM_001180462.1_CBS436 cds-NP_010439.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:725684-726172:- gene-YDR155C_CBS6412 rna-NM_001180462.1_CBS6412 cds-NP_010439.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:754100-754588:- gene-YDR155C_CBS6413 rna-NM_001180462.1_CBS6413 cds-NP_010439.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:769201-769689:- gene-YDR155C_CENPK1137D rna-NM_001180462.1_CENPK1137D cds-NP_010439.1_CENPK1137D 99.7 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:739660-740148:- gene-YDR155C_EthanolRed rna-NM_001180462.1_EthanolRed cds-NP_010439.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:747872-748360:- gene-YDR155C_FaliES1 rna-NM_001180462.1_FaliES1 cds-NP_010439.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000401.1:8787-9275:- gene-YDR155C_JAY291 rna-NM_001180462.1_JAY291 cds-NP_010439.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:756302-756790:- gene-YDR155C_MUCL30387 rna-NM_001180462.1_MUCL30387 cds-NP_010439.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:745219-745707:- gene-YDR155C_MUCL30388 rna-NM_001180462.1_MUCL30388 cds-NP_010439.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:731629-732117:- gene-YDR155C_MUCL39482 rna-NM_001180462.1_MUCL39482 cds-NP_010439.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:669454-669942:- gene-YDR155C_MUCL42920 rna-NM_001180462.1_MUCL42920 cds-NP_010439.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:768435-768923:- gene-YDR155C_NCIM3186 rna-NM_001180462.1_NCIM3186 cds-NP_010439.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:731033-731521:- gene-YDR155C_NCYC1407 rna-NM_001180462.1_NCYC1407 cds-NP_010439.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:750221-750709:- gene-YDR155C_PE2H3 rna-NM_001180462.1_PE2H3 cds-NP_010439.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:749526-750014:- gene-YDR155C_PE2H4 rna-NM_001180462.1_PE2H4 cds-NP_010439.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:768512-769000:- gene-YDR155C_S288C rna-NM_001180462.1_S288C cds-NP_010439.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000009.1:115732-116220:- gene-YDR155C_SA1 rna-NM_001180462.1_SA1 cds-NP_010439.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:746007-746495:- gene-YDR155C_ThermosaccDry rna-NM_001180462.1_ThermosaccDry cds-NP_010439.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:760933-761421:- gene-YDR155C_VR1 rna-NM_001180462.1_VR1 cds-NP_010439.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000007.1:8759-9247:- gene-YDR155C_ZTW1 rna-NM_001180462.1_ZTW1 cds-NP_010439.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:752279-752767:- gene-YDR155C_Sparadoxus rna-NM_001180462.1_Sparadoxus cds-NP_010439.1_Sparadoxus 95.7 100.0 Verified 1 1 1 True True False False False

Additional files