Gene name: COX18
Reference locus (S288C): YGR062C
Gene biotype: protein_coding
Description: Protein required for membrane insertion of C-terminus of Cox2p; mitochondrial integral inner membrane protein; interacts genetically and physically with Mss2p and Pnt1p; similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E. coli YidC; respiratory defect of the null mutant is functionally complemented by human COX18 carrying the N-terminal 54 amino acids of S. cerevisiae Cox18p; Belongs to the OXA1/ALB3/YidC family
Top 10 interactors (score): COX20 (0.989); OXA1 (0.984); RIP1 (0.979); TOM40 (0.973); COR1 (0.968); PNT1 (0.967); COX2 (0.964); CYT1 (0.96); MSS2 (0.958); QCR2 (0.957); QCR6 (0.952); BI4 (0.946); COB (0.941); YML6 (0.922); QCR7 (0.914); NDI1 (0.914); COX17 (0.913); NDE2 (0.909); QCR8 (0.906); NDE1 (0.906)
Homologues (species, bitscore): COX18 (Homo sapiens, 56.6); Cox18 (Mus musculus, 58.5); COX18 (Danio rerio, 61.2); cox18 (Xenopus tropicalis, 64.3); CG4942 (Drosophila melanogaster, 61.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:600020-600970:- | gene-YGR062C_AKU4011 | rna-NM_001181191.1_AKU4011 | cds-NP_011576.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:36348-37298:- | gene-YGR062C_BG1 | rna-NM_001181191.1_BG1 | cds-NP_011576.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:602308-603258:- | gene-YGR062C_Bruggeman | rna-NM_001181191.1_Bruggeman | cds-NP_011576.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:600734-601684:- | gene-YGR062C_CAT1 | rna-NM_001181191.1_CAT1 | cds-NP_011576.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:601334-602284:- | gene-YGR062C_CBS1585 | rna-NM_001181191.1_CBS1585 | cds-NP_011576.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:602630-603580:- | gene-YGR062C_CBS436 | rna-NM_001181191.1_CBS436 | cds-NP_011576.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:594129-595079:- | gene-YGR062C_CBS6412 | rna-NM_001181191.1_CBS6412 | cds-NP_011576.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:598127-599077:- | gene-YGR062C_CBS6413 | rna-NM_001181191.1_CBS6413 | cds-NP_011576.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:616048-616998:- | gene-YGR062C_CENPK1137D | rna-NM_001181191.1_CENPK1137D | cds-NP_011576.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:588263-589213:- | gene-YGR062C_EthanolRed | rna-NM_001181191.1_EthanolRed | cds-NP_011576.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:591742-592692:- | gene-YGR062C_FaliES1 | rna-NM_001181191.1_FaliES1 | cds-NP_011576.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000435.1:42689-43639:- | gene-YGR062C_JAY291 | rna-NM_001181191.1_JAY291 | cds-NP_011576.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:598940-599890:- | gene-YGR062C_MUCL30387 | rna-NM_001181191.1_MUCL30387 | cds-NP_011576.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:602338-603288:- | gene-YGR062C_MUCL30388 | rna-NM_001181191.1_MUCL30388 | cds-NP_011576.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:597171-598121:- | gene-YGR062C_MUCL39482 | rna-NM_001181191.1_MUCL39482 | cds-NP_011576.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:606965-607915:- | gene-YGR062C_MUCL42920 | rna-NM_001181191.1_MUCL42920 | cds-NP_011576.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:616328-617278:- | gene-YGR062C_NCIM3186 | rna-NM_001181191.1_NCIM3186 | cds-NP_011576.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:591349-592299:- | gene-YGR062C_NCYC1407 | rna-NM_001181191.1_NCYC1407 | cds-NP_011576.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:594594-595544:- | gene-YGR062C_PE2H3 | rna-NM_001181191.1_PE2H3 | cds-NP_011576.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:599701-600651:- | gene-YGR062C_PE2H4 | rna-NM_001181191.1_PE2H4 | cds-NP_011576.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:616328-617278:- | gene-YGR062C_S288C | rna-NM_001181191.1_S288C | cds-NP_011576.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:42793-43743:- | gene-YGR062C_SA1 | rna-NM_001181191.1_SA1 | cds-NP_011576.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:611080-612030:- | gene-YGR062C_ThermosaccDry | rna-NM_001181191.1_ThermosaccDry | cds-NP_011576.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:708015-708965:- | gene-YGR062C_VR1 | rna-NM_001181191.1_VR1 | cds-NP_011576.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:66546-67496:- | gene-YGR062C_ZTW1 | rna-NM_001181191.1_ZTW1 | cds-NP_011576.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:601509-602459:- | gene-YGR062C_Sparadoxus | rna-NM_001181191.1_Sparadoxus | cds-NP_011576.1_Sparadoxus | 87.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |