Gene name: COX12
Reference locus (S288C): YLR038C
Gene biotype: protein_coding
Description: Subunit VIb of cytochrome c oxidase; cytochrome c oxidase is also known as respiratory Complex IV and is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of cytochrome c oxidase but not required for activity after assembly; phosphorylated; easily released from the intermembrane space, suggesting a loose association with Complex IV
Top 10 interactors (score): COX3 (0.999); RIP1 (0.999); ATP20 (0.999); COX1 (0.999); RCF1 (0.999); COX4 (0.999); COX8 (0.999); COR1 (0.999); QCR2 (0.999); CYT1 (0.999); QCR8 (0.999); QCR9 (0.999); COX13 (0.999); COX5A (0.999); COX2 (0.999); QCR7 (0.999); COB (0.999); COX7 (0.999); COX9 (0.999); QCR10 (0.999)
Homologues (species, bitscore): COX6B1 (Homo sapiens, 83.6); Cox6b2 (Mus musculus, 84.0); cox6b1 (Danio rerio, 95.9); cox6b1 (Xenopus tropicalis, 56.6); COX6B (Drosophila melanogaster, 101.7); Y71H2AM.5 (Caenorhabditis elegans, 69.3); COX6B (Arabidopsis thaliana, 89.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:207409-207660:- | gene-YLR038C_AKU4011 | rna-NM_001181925.1_AKU4011 | cds-NP_013139.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:170554-170805:- | gene-YLR038C_BG1 | rna-NM_001181925.1_BG1 | cds-NP_013139.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:217317-217568:- | gene-YLR038C_Bruggeman | rna-NM_001181925.1_Bruggeman | cds-NP_013139.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:217643-217894:- | gene-YLR038C_CAT1 | rna-NM_001181925.1_CAT1 | cds-NP_013139.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:214547-214798:- | gene-YLR038C_CBS1585 | rna-NM_001181925.1_CBS1585 | cds-NP_013139.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:205181-205432:- | gene-YLR038C_CBS436 | rna-NM_001181925.1_CBS436 | cds-NP_013139.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:212956-213207:- | gene-YLR038C_CBS6412 | rna-NM_001181925.1_CBS6412 | cds-NP_013139.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:214808-215059:- | gene-YLR038C_CBS6413 | rna-NM_001181925.1_CBS6413 | cds-NP_013139.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:204216-204467:- | gene-YLR038C_CENPK1137D | rna-NM_001181925.1_CENPK1137D | cds-NP_013139.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:206933-207184:- | gene-YLR038C_EthanolRed | rna-NM_001181925.1_EthanolRed | cds-NP_013139.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:206819-207070:- | gene-YLR038C_FaliES1 | rna-NM_001181925.1_FaliES1 | cds-NP_013139.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000289.1:8502-8753:+ | gene-YLR038C_JAY291 | rna-NM_001181925.1_JAY291 | cds-NP_013139.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:214670-214921:- | gene-YLR038C_MUCL30387 | rna-NM_001181925.1_MUCL30387 | cds-NP_013139.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:221922-222173:- | gene-YLR038C_MUCL30388 | rna-NM_001181925.1_MUCL30388 | cds-NP_013139.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:215042-215293:- | gene-YLR038C_MUCL39482 | rna-NM_001181925.1_MUCL39482 | cds-NP_013139.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:214947-215198:- | gene-YLR038C_MUCL42920 | rna-NM_001181925.1_MUCL42920 | cds-NP_013139.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:224895-225146:- | gene-YLR038C_NCIM3186 | rna-NM_001181925.1_NCIM3186 | cds-NP_013139.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:207101-207352:- | gene-YLR038C_NCYC1407 | rna-NM_001181925.1_NCYC1407 | cds-NP_013139.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:212978-213229:- | gene-YLR038C_PE2H3 | rna-NM_001181925.1_PE2H3 | cds-NP_013139.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:212719-212970:- | gene-YLR038C_PE2H4 | rna-NM_001181925.1_PE2H4 | cds-NP_013139.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:224921-225172:- | gene-YLR038C_S288C | rna-NM_001181925.1_S288C | cds-NP_013139.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000046.1:50821-51072:- | gene-YLR038C_SA1 | rna-NM_001181925.1_SA1 | cds-NP_013139.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:207007-207258:- | gene-YLR038C_ThermosaccDry | rna-NM_001181925.1_ThermosaccDry | cds-NP_013139.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:220425-220676:- | gene-YLR038C_VR1 | rna-NM_001181925.1_VR1 | cds-NP_013139.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:206354-206605:- | gene-YLR038C_ZTW1 | rna-NM_001181925.1_ZTW1 | cds-NP_013139.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:215230-215481:- | gene-YLR038C_Sparadoxus | rna-NM_001181925.1_Sparadoxus | cds-NP_013139.1_Sparadoxus | 93.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |