Gene name: COX10
Reference locus (S288C): YPL172C
Gene biotype: protein_coding
Description: Protoheme IX farnesyltransferase, mitochondrial; Heme A:farnesyltransferase; catalyzes first step in conversion of protoheme to heme A prosthetic group required for cytochrome c oxidase activity; human ortholog COX10 can complement yeast cox10 null mutant; human ortholog COX10 is associated with mitochondrial disorders
Top 10 interactors (score): COX15 (0.999); SHY1 (0.994); CYT1 (0.982); HEM15 (0.979); CYT2 (0.975); SCO2 (0.972); YAH1 (0.967); COX1 (0.965); CYC3 (0.956); COX11 (0.947); SDH2 (0.935); COQ2 (0.933); COX17 (0.929); COX2 (0.928); COX6 (0.922); ARH1 (0.919); COX20 (0.907); SCO1 (0.905); COX3 (0.888); SDH1 (0.847)
Homologues (species, bitscore): COX10 (Homo sapiens, 206.5); Cox10 (Mus musculus, 201.1); cox10 (Danio rerio, 215.7); ENSXETP00000062611 (Xenopus tropicalis, 102.1); CG5037 (Drosophila melanogaster, 229.2); cox-10 (Caenorhabditis elegans, 216.5); COX10 (Arabidopsis thaliana, 149.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:202025-203413:- | gene-YPL172C_AKU4011 | rna-NM_001183986.1_AKU4011 | cds-NP_015153.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:407686-409074:- | gene-YPL172C_BG1 | rna-NM_001183986.1_BG1 | cds-NP_015153.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:227905-229293:- | gene-YPL172C_Bruggeman | rna-NM_001183986.1_Bruggeman | cds-NP_015153.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:224680-226068:- | gene-YPL172C_CAT1 | rna-NM_001183986.1_CAT1 | cds-NP_015153.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:206087-207475:- | gene-YPL172C_CBS1585 | rna-NM_001183986.1_CBS1585 | cds-NP_015153.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:220743-222131:- | gene-YPL172C_CBS436 | rna-NM_001183986.1_CBS436 | cds-NP_015153.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:210763-212151:- | gene-YPL172C_CBS6412 | rna-NM_001183986.1_CBS6412 | cds-NP_015153.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:202726-204114:- | gene-YPL172C_CBS6413 | rna-NM_001183986.1_CBS6413 | cds-NP_015153.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:224237-225625:- | gene-YPL172C_CENPK1137D | rna-NM_001183986.1_CENPK1137D | cds-NP_015153.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:200765-202153:- | gene-YPL172C_EthanolRed | rna-NM_001183986.1_EthanolRed | cds-NP_015153.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:208357-209745:- | gene-YPL172C_FaliES1 | rna-NM_001183986.1_FaliES1 | cds-NP_015153.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000007.1:156164-157552:+ | gene-YPL172C_JAY291 | rna-NM_001183986.1_JAY291 | cds-NP_015153.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:219252-220640:- | gene-YPL172C_MUCL30387 | rna-NM_001183986.1_MUCL30387 | cds-NP_015153.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:217273-218661:- | gene-YPL172C_MUCL30388 | rna-NM_001183986.1_MUCL30388 | cds-NP_015153.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:199416-200804:- | gene-YPL172C_MUCL39482 | rna-NM_001183986.1_MUCL39482 | cds-NP_015153.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:256140-257528:- | gene-YPL172C_MUCL42920 | rna-NM_001183986.1_MUCL42920 | cds-NP_015153.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:224336-225724:- | gene-YPL172C_NCIM3186 | rna-NM_001183986.1_NCIM3186 | cds-NP_015153.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:205872-207260:- | gene-YPL172C_NCYC1407 | rna-NM_001183986.1_NCYC1407 | cds-NP_015153.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:213305-214693:- | gene-YPL172C_PE2H3 | rna-NM_001183986.1_PE2H3 | cds-NP_015153.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:212948-214336:- | gene-YPL172C_PE2H4 | rna-NM_001183986.1_PE2H4 | cds-NP_015153.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:224353-225741:- | gene-YPL172C_S288C | rna-NM_001183986.1_S288C | cds-NP_015153.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000012.1:147939-149327:+ | gene-YPL172C_SA1 | rna-NM_001183986.1_SA1 | cds-NP_015153.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:208155-209543:- | gene-YPL172C_ThermosaccDry | rna-NM_001183986.1_ThermosaccDry | cds-NP_015153.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:223078-224466:- | gene-YPL172C_VR1 | rna-NM_001183986.1_VR1 | cds-NP_015153.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:207484-208872:- | gene-YPL172C_ZTW1 | rna-NM_001183986.1_ZTW1 | cds-NP_015153.1_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:209070-210458:- | gene-YPL172C_Sparadoxus | rna-NM_001183986.1_Sparadoxus | cds-NP_015153.1_Sparadoxus | 90.5 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |