COS2 (YBR302C)

Gene profile

Gene name: COS2
Reference locus (S288C): YBR302C
Gene biotype: protein_coding

Description: Cos2p; Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins

Top 10 interactors (score): COS3 (0.988); COS4 (0.975); COS1 (0.969); COS8 (0.901); COS7 (0.852); COS5 (0.852); YRF1-7 (0.712); PAU24 (0.711); IMA1 (0.592); SNA3 (0.574); BIO2 (0.574); MAL33 (0.569); BSD2 (0.568); MAL32 (0.563); MAL31 (0.481); ZUO1 (0.451)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
UCSC Genome Browser

Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:797812-798939:- gene-YBR302C_Bruggeman rna-NM_001178650.1_Bruggeman cds-NP_009861.1_Bruggeman 90.3 96.1 Verified 1 1 0 False False False True False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:804767-805078:- gene-YBR302C_CENPK1137D rna-NM_001178650.1_CENPK1137D cds-NP_009861.1_CENPK1137D 27.3 27.3 Verified 1 1 0 False False True False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:1-453:+ gene-YBR302C_FaliES1 rna-NM_001178650.1_FaliES1 cds-NP_009861.1_FaliES1 36.7 39.1 Mismatch 1 1 0 False False True False False
MUCL39482 GCA_001738235.1 Sake Asia MBVN01000062.1:116-464:+ gene-YBR302C_MUCL39482 rna-NM_001178650.1_MUCL39482 cds-NP_009861.1_MUCL39482 29.7 30.6 Mismatch 1 1 0 False False False True False
MUCL42920 GCA_001738485.1 Bread Europe MBVV01000015.1:1-729:- gene-YBR302C_MUCL42920 rna-NM_001178650.1_MUCL42920 cds-NP_009861.1_MUCL42920 61.0 63.9 Mismatch 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:810137-811276:- gene-YBR302C_NCIM3186 rna-NM_001178650.1_NCIM3186 cds-NP_009861.1_NCIM3186 86.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:1111935-1112983:- gene-YBR302C_PE2H4 rna-NM_001178650.1_PE2H4 cds-NP_009861.1_PE2H4 71.1 85.1 Unannotated 1 1 0 False False False True False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:810340-811479:- gene-YBR302C_S288C rna-NM_001178650.1_S288C cds-NP_009861.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000163.1:1773-2438:+ gene-YBR302C_SA1 rna-NM_001178650.1_SA1 cds-NP_009861.1_SA1 53.4 58.4 Unannotated 1 1 0 False False False True False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:8649-9631:+ gene-YBR302C_VR1 rna-NM_001178650.1_VR1 cds-NP_009861.1_VR1 73.1 84.5 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:772522-773672:- gene-YBR302C_Sparadoxus rna-NM_001178650.1_Sparadoxus cds-NP_009861.1_Sparadoxus 80.3 98.9 Unannotated 1 1 0 False False False True False

Additional files