Gene name: COS2
Reference locus (S288C): YBR302C
Gene biotype: protein_coding
Description: Cos2p; Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
Top 10 interactors (score): COS3 (0.988); COS4 (0.975); COS1 (0.969); COS8 (0.901); COS7 (0.852); COS5 (0.852); YRF1-7 (0.712); PAU24 (0.711); IMA1 (0.592); SNA3 (0.574); BIO2 (0.574); MAL33 (0.569); BSD2 (0.568); MAL32 (0.563); MAL31 (0.481); ZUO1 (0.451)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:797812-798939:- | gene-YBR302C_Bruggeman | rna-NM_001178650.1_Bruggeman | cds-NP_009861.1_Bruggeman | 90.3 | 96.1 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:804767-805078:- | gene-YBR302C_CENPK1137D | rna-NM_001178650.1_CENPK1137D | cds-NP_009861.1_CENPK1137D | 27.3 | 27.3 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:1-453:+ | gene-YBR302C_FaliES1 | rna-NM_001178650.1_FaliES1 | cds-NP_009861.1_FaliES1 | 36.7 | 39.1 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | MBVN01000062.1:116-464:+ | gene-YBR302C_MUCL39482 | rna-NM_001178650.1_MUCL39482 | cds-NP_009861.1_MUCL39482 | 29.7 | 30.6 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000015.1:1-729:- | gene-YBR302C_MUCL42920 | rna-NM_001178650.1_MUCL42920 | cds-NP_009861.1_MUCL42920 | 61.0 | 63.9 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:810137-811276:- | gene-YBR302C_NCIM3186 | rna-NM_001178650.1_NCIM3186 | cds-NP_009861.1_NCIM3186 | 86.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:1111935-1112983:- | gene-YBR302C_PE2H4 | rna-NM_001178650.1_PE2H4 | cds-NP_009861.1_PE2H4 | 71.1 | 85.1 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:810340-811479:- | gene-YBR302C_S288C | rna-NM_001178650.1_S288C | cds-NP_009861.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000163.1:1773-2438:+ | gene-YBR302C_SA1 | rna-NM_001178650.1_SA1 | cds-NP_009861.1_SA1 | 53.4 | 58.4 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:8649-9631:+ | gene-YBR302C_VR1 | rna-NM_001178650.1_VR1 | cds-NP_009861.1_VR1 | 73.1 | 84.5 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:772522-773672:- | gene-YBR302C_Sparadoxus | rna-NM_001178650.1_Sparadoxus | cds-NP_009861.1_Sparadoxus | 80.3 | 98.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |