Gene name: COS1
Reference locus (S288C): YNL336W
Gene biotype: protein_coding
Description: Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family
Top 10 interactors (score): COS4 (0.988); COS2 (0.969); COS3 (0.927); COS8 (0.881); COS7 (0.872); COS5 (0.823); MIP6 (0.45)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:465-1553:+ | gene-YNL336W_AKU4011 | rna-NM_001183174.1_AKU4011 | cds-NP_014063.1_AKU4011 | 89.0 | 94.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | MBWC01000325.1:1-659:- | gene-YNL336W_CAT1 | rna-NM_001183174.1_CAT1 | cds-NP_014063.1_CAT1 | 55.4 | 57.5 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:781780-782925:- | gene-YNL336W_CBS1585 | rna-NM_001183174.1_CBS1585 | cds-NP_014063.1_CBS1585 | 97.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:3040-4189:+ | gene-YNL336W_CBS6412 | rna-NM_001183174.1_CBS6412 | cds-NP_014063.1_CBS6412 | 92.9 | 99.4 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:790276-791421:- | gene-YNL336W_CBS6413 | rna-NM_001183174.1_CBS6413 | cds-NP_014063.1_CBS6413 | 97.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:1780-2925:+ | gene-YNL336W_EthanolRed | rna-NM_001183174.1_EthanolRed | cds-NP_014063.1_EthanolRed | 97.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | MBWD01000102.1:49-980:+ | gene-YNL336W_FaliES1 | rna-NM_001183174.1_FaliES1 | cds-NP_014063.1_FaliES1 | 78.4 | 81.3 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000392.1:149-595:+ | gene-YNL336W_JAY291 | rna-NM_001183174.1_JAY291 | cds-NP_014063.1_JAY291 | 38.9 | 39.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:731844-732993:- | gene-YNL336W_MUCL30387 | rna-NM_001183174.1_MUCL30387 | cds-NP_014063.1_MUCL30387 | 58.3 | 93.2 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:817903-818996:- | gene-YNL336W_MUCL30388 | rna-NM_001183174.1_MUCL30388 | cds-NP_014063.1_MUCL30388 | 57.2 | 73.7 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | MBVN01000084.1:14636-15781:- | gene-YNL336W_MUCL39482 | rna-NM_001183174.1_MUCL39482 | cds-NP_014063.1_MUCL39482 | 87.0 | 98.7 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:8299-9444:+ | gene-YNL336W_NCIM3186 | rna-NM_001183174.1_NCIM3186 | cds-NP_014063.1_NCIM3186 | 50.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:2823-3934:+ | gene-YNL336W_NCYC1407 | rna-NM_001183174.1_NCYC1407 | cds-NP_014063.1_NCYC1407 | 94.0 | 97.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:727921-729066:- | gene-YNL336W_PE2H3 | rna-NM_001183174.1_PE2H3 | cds-NP_014063.1_PE2H3 | 97.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:431510-432655:- | gene-YNL336W_PE2H4 | rna-NM_001183174.1_PE2H4 | cds-NP_014063.1_PE2H4 | 93.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:8330-9475:+ | gene-YNL336W_S288C | rna-NM_001183174.1_S288C | cds-NP_014063.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:49-1443:+ | gene-YNL336W_ThermosaccDry | rna-NM_001183174.1_ThermosaccDry | cds-NP_014063.1_ThermosaccDry | 79.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:13246-14294:+ | gene-YNL336W_VR1 | rna-NM_001183174.1_VR1 | cds-NP_014063.1_VR1 | 80.1 | 88.4 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:433250-434388:- | gene-YNL336W_Sparadoxus | rna-NM_001183174.1_Sparadoxus | cds-NP_014063.1_Sparadoxus | 78.5 | 98.4 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |