Gene name: COQ6
Reference locus (S288C): YGR255C
Gene biotype: protein_coding
Description: Flavin-dependent monooxygenase involved in ubiquinone biosynthesis; responsible for hydroxylation at position C5 and deamination at C4 during ubiquinone (Coenzyme Q) biosynthesis; localizes to matrix face of mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; human homolog COQ6 can complement yeast null mutant and is implicated in steroid-resistant nephrotic syndrome (SRNS); Belongs to the UbiH/COQ6 family
Top 10 interactors (score): COQ5 (0.999); CAT5 (0.998); COQ3 (0.998); COQ8 (0.998); COQ9 (0.998); COQ4 (0.996); COQ2 (0.995); COQ1 (0.993); FMO1 (0.97); YAH1 (0.966); COQ11 (0.93); ATP2 (0.823); PUF3 (0.808); FLX1 (0.786); MCP2 (0.785); COQ10 (0.777); CIR2 (0.742); YPL109C (0.735); FAD1 (0.732); YGR273C (0.71)
Homologues (species, bitscore): COQ6 (Homo sapiens, 233.0); Coq6 (Mus musculus, 239.6); coq6 (Danio rerio, 242.3); coq6 (Xenopus tropicalis, 241.5); CG7277 (Drosophila melanogaster, 196.1); coq-6 (Caenorhabditis elegans, 222.2); AT3G24200 (Arabidopsis thaliana, 191.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:967952-969391:- | gene-YGR255C_AKU4011 | rna-NM_001181384.1_AKU4011 | cds-NP_011771.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:248121-249560:- | gene-YGR255C_BG1 | rna-NM_001181384.1_BG1 | cds-NP_011771.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:976469-977908:- | gene-YGR255C_Bruggeman | rna-NM_001181384.1_Bruggeman | cds-NP_011771.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:975406-976845:- | gene-YGR255C_CAT1 | rna-NM_001181384.1_CAT1 | cds-NP_011771.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:970822-972261:- | gene-YGR255C_CBS1585 | rna-NM_001181384.1_CBS1585 | cds-NP_011771.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:974451-975890:- | gene-YGR255C_CBS436 | rna-NM_001181384.1_CBS436 | cds-NP_011771.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:961712-963151:- | gene-YGR255C_CBS6412 | rna-NM_001181384.1_CBS6412 | cds-NP_011771.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:967767-969206:- | gene-YGR255C_CBS6413 | rna-NM_001181384.1_CBS6413 | cds-NP_011771.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:1002204-1003643:- | gene-YGR255C_CENPK1137D | rna-NM_001181384.1_CENPK1137D | cds-NP_011771.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:955803-957242:- | gene-YGR255C_EthanolRed | rna-NM_001181384.1_EthanolRed | cds-NP_011771.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:960609-962048:- | gene-YGR255C_FaliES1 | rna-NM_001181384.1_FaliES1 | cds-NP_011771.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:68264-69703:+ | gene-YGR255C_JAY291 | rna-NM_001181384.1_JAY291 | cds-NP_011771.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:974206-975645:- | gene-YGR255C_MUCL30387 | rna-NM_001181384.1_MUCL30387 | cds-NP_011771.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:972338-973777:- | gene-YGR255C_MUCL30388 | rna-NM_001181384.1_MUCL30388 | cds-NP_011771.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:965928-967367:- | gene-YGR255C_MUCL39482 | rna-NM_001181384.1_MUCL39482 | cds-NP_011771.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:983800-985239:- | gene-YGR255C_MUCL42920 | rna-NM_001181384.1_MUCL42920 | cds-NP_011771.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:1002523-1003962:- | gene-YGR255C_NCIM3186 | rna-NM_001181384.1_NCIM3186 | cds-NP_011771.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:961557-962996:- | gene-YGR255C_NCYC1407 | rna-NM_001181384.1_NCYC1407 | cds-NP_011771.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:986744-988183:- | gene-YGR255C_PE2H3 | rna-NM_001181384.1_PE2H3 | cds-NP_011771.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:991583-993022:- | gene-YGR255C_PE2H4 | rna-NM_001181384.1_PE2H4 | cds-NP_011771.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:1002523-1003962:- | gene-YGR255C_S288C | rna-NM_001181384.1_S288C | cds-NP_011771.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000063.1:741-2180:- | gene-YGR255C_SA1 | rna-NM_001181384.1_SA1 | cds-NP_011771.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:981129-982568:- | gene-YGR255C_ThermosaccDry | rna-NM_001181384.1_ThermosaccDry | cds-NP_011771.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1086907-1088346:- | gene-YGR255C_VR1 | rna-NM_001181384.1_VR1 | cds-NP_011771.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:282541-283980:- | gene-YGR255C_ZTW1 | rna-NM_001181384.1_ZTW1 | cds-NP_011771.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:973081-974520:- | gene-YGR255C_Sparadoxus | rna-NM_001181384.1_Sparadoxus | cds-NP_011771.1_Sparadoxus | 91.4 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |