Gene name: COQ5
Reference locus (S288C): YML110C
Gene biotype: protein_coding
Description: 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase; involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; respiratory defect of the null mutant is partially complemented by human COQ5; Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family
Top 10 interactors (score): COQ6 (0.999); COQ1 (0.999); CAT5 (0.999); COQ3 (0.998); COQ9 (0.998); COQ8 (0.997); COQ4 (0.996); COQ2 (0.995); MAS1 (0.965); COQ11 (0.906); PUF3 (0.898); YAH1 (0.862); COX15 (0.847); YPL109C (0.844); COX11 (0.802); FMO1 (0.799); TAR1 (0.796); ATP2 (0.789); RIP1 (0.778); HFD1 (0.775)
Homologues (species, bitscore): COQ5 (Homo sapiens, 228.8); Coq5 (Mus musculus, 223.0); COQ5 (Danio rerio, 230.7); coq5 (Xenopus tropicalis, 213.8); CG2453 (Drosophila melanogaster, 237.7); coq-5 (Caenorhabditis elegans, 210.3); AT5G57300 (Arabidopsis thaliana, 219.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:43746-44669:- | gene-YML110C_AKU4011 | rna-NM_001182472.1_AKU4011 | cds-NP_013597.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:431451-432374:+ | gene-YML110C_BG1 | rna-NM_001182472.1_BG1 | cds-NP_013597.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:50009-50932:- | gene-YML110C_Bruggeman | rna-NM_001182472.1_Bruggeman | cds-NP_013597.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:51564-52487:- | gene-YML110C_CAT1 | rna-NM_001182472.1_CAT1 | cds-NP_013597.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:43747-44670:- | gene-YML110C_CBS1585 | rna-NM_001182472.1_CBS1585 | cds-NP_013597.1_CBS1585 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:49747-50670:- | gene-YML110C_CBS436 | rna-NM_001182472.1_CBS436 | cds-NP_013597.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:44510-45433:- | gene-YML110C_CBS6412 | rna-NM_001182472.1_CBS6412 | cds-NP_013597.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:42974-43897:- | gene-YML110C_CBS6413 | rna-NM_001182472.1_CBS6413 | cds-NP_013597.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:44590-45513:- | gene-YML110C_CENPK1137D | rna-NM_001182472.1_CENPK1137D | cds-NP_013597.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:44256-45179:- | gene-YML110C_EthanolRed | rna-NM_001182472.1_EthanolRed | cds-NP_013597.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:44532-45455:- | gene-YML110C_FaliES1 | rna-NM_001182472.1_FaliES1 | cds-NP_013597.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000345.1:44722-45645:+ | gene-YML110C_JAY291 | rna-NM_001182472.1_JAY291 | cds-NP_013597.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:48459-49382:- | gene-YML110C_MUCL30387 | rna-NM_001182472.1_MUCL30387 | cds-NP_013597.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:51679-52602:- | gene-YML110C_MUCL30388 | rna-NM_001182472.1_MUCL30388 | cds-NP_013597.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:43762-44685:- | gene-YML110C_MUCL39482 | rna-NM_001182472.1_MUCL39482 | cds-NP_013597.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:47926-48849:- | gene-YML110C_MUCL42920 | rna-NM_001182472.1_MUCL42920 | cds-NP_013597.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:49985-50908:- | gene-YML110C_NCIM3186 | rna-NM_001182472.1_NCIM3186 | cds-NP_013597.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:44556-45479:- | gene-YML110C_NCYC1407 | rna-NM_001182472.1_NCYC1407 | cds-NP_013597.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:49998-50921:- | gene-YML110C_PE2H3 | rna-NM_001182472.1_PE2H3 | cds-NP_013597.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:49936-50859:- | gene-YML110C_PE2H4 | rna-NM_001182472.1_PE2H4 | cds-NP_013597.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:50031-50954:- | gene-YML110C_S288C | rna-NM_001182472.1_S288C | cds-NP_013597.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000054.1:42013-42936:- | gene-YML110C_SA1 | rna-NM_001182472.1_SA1 | cds-NP_013597.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:43831-44754:- | gene-YML110C_ThermosaccDry | rna-NM_001182472.1_ThermosaccDry | cds-NP_013597.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:48218-49141:- | gene-YML110C_VR1 | rna-NM_001182472.1_VR1 | cds-NP_013597.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:23316-24239:- | gene-YML110C_ZTW1 | rna-NM_001182472.1_ZTW1 | cds-NP_013597.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:54800-55723:- | gene-YML110C_Sparadoxus | rna-NM_001182472.1_Sparadoxus | cds-NP_013597.1_Sparadoxus | 91.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |