COG4 (YPR105C)


Gene profile

Gene name: COG4
Reference locus (S288C): YPR105C
Gene biotype: protein_coding

Description: Conserved oligomeric golgi complex subunit 4; Essential component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments

Top 10 interactors (score): COG2 (0.999); COG3 (0.999); COG8 (0.999); COG6 (0.999); COG1 (0.998); SLY1 (0.997); COG5 (0.995); COG7 (0.989); VPS53 (0.983); VPS54 (0.982); SED5 (0.972); VPS52 (0.945); TIP20 (0.911); YKT6 (0.899); SEC6 (0.897); GOS1 (0.89); EXO70 (0.88); BET1 (0.876); SEC22 (0.874); ATG17 (0.868)

Homologues (species, bitscore): COG4 (Homo sapiens, 85.1); Cog4 (Mus musculus, 83.6); cog4 (Danio rerio, 86.3); cog4 (Xenopus tropicalis, 88.2); CG7456 (Drosophila melanogaster, 86.7); cogc-4 (Caenorhabditis elegans, 63.5); AT4G01400 (Arabidopsis thaliana, 76.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:708820-711405:- gene-YPR105C_AKU4011 rna-NM_001184202.1_AKU4011 cds-NP_015430.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:186438-189023:+ gene-YPR105C_BG1 rna-NM_001184202.1_BG1 cds-NP_015430.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:786829-789414:- gene-YPR105C_Bruggeman rna-NM_001184202.1_Bruggeman cds-NP_015430.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:831129-833714:- gene-YPR105C_CAT1 rna-NM_001184202.1_CAT1 cds-NP_015430.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:713077-715662:- gene-YPR105C_CBS1585 rna-NM_001184202.1_CBS1585 cds-NP_015430.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:727371-729956:- gene-YPR105C_CBS436 rna-NM_001184202.1_CBS436 cds-NP_015430.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:715313-717898:- gene-YPR105C_CBS6412 rna-NM_001184202.1_CBS6412 cds-NP_015430.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:710034-712619:- gene-YPR105C_CBS6413 rna-NM_001184202.1_CBS6413 cds-NP_015430.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:736969-739554:- gene-YPR105C_CENPK1137D rna-NM_001184202.1_CENPK1137D cds-NP_015430.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:1035434-1038019:- gene-YPR105C_EthanolRed rna-NM_001184202.1_EthanolRed cds-NP_015430.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:714981-717566:- gene-YPR105C_FaliES1 rna-NM_001184202.1_FaliES1 cds-NP_015430.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000436.1:5740-8325:- gene-YPR105C_JAY291 rna-NM_001184202.1_JAY291 cds-NP_015430.1_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:728087-730672:- gene-YPR105C_MUCL30387 rna-NM_001184202.1_MUCL30387 cds-NP_015430.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:726777-729362:- gene-YPR105C_MUCL30388 rna-NM_001184202.1_MUCL30388 cds-NP_015430.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:705584-708169:- gene-YPR105C_MUCL39482 rna-NM_001184202.1_MUCL39482 cds-NP_015430.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:768679-771264:- gene-YPR105C_MUCL42920 rna-NM_001184202.1_MUCL42920 cds-NP_015430.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:736967-739552:- gene-YPR105C_NCIM3186 rna-NM_001184202.1_NCIM3186 cds-NP_015430.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:714178-716763:- gene-YPR105C_NCYC1407 rna-NM_001184202.1_NCYC1407 cds-NP_015430.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:720415-723000:- gene-YPR105C_PE2H3 rna-NM_001184202.1_PE2H3 cds-NP_015430.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:720063-722648:- gene-YPR105C_PE2H4 rna-NM_001184202.1_PE2H4 cds-NP_015430.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:736984-739569:- gene-YPR105C_S288C rna-NM_001184202.1_S288C cds-NP_015430.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000028.1:35103-37688:- gene-YPR105C_SA1 rna-NM_001184202.1_SA1 cds-NP_015430.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:714426-717011:- gene-YPR105C_ThermosaccDry rna-NM_001184202.1_ThermosaccDry cds-NP_015430.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:731082-733667:- gene-YPR105C_VR1 rna-NM_001184202.1_VR1 cds-NP_015430.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:713476-716061:- gene-YPR105C_ZTW1 rna-NM_001184202.1_ZTW1 cds-NP_015430.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:714405-716990:- gene-YPR105C_Sparadoxus rna-NM_001184202.1_Sparadoxus cds-NP_015430.1_Sparadoxus 89.4 99.9 Verified 1 1 1 False True False False False

Additional files