Gene name: COA6
Reference locus (S288C): YMR244C-A
Gene biotype: protein_coding
Description: Protein involved in cytochrome c oxidase (Complex IV) assembly; involved in delivery of copper to Complex IV; also required for efficient formation of respiratory supercomplexes comprised of Complexes III and IV; localizes to the mitochondrial intermembrane space; ortholog implicated in cardiac defects in zebrafish and human; transcription is induced in response to the DNA-damaging agent MMS; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): MIX14 (0.972); COX19 (0.968); MIX17 (0.966); TIM9 (0.959); MIA40 (0.95); TIM10 (0.948); ERV1 (0.946); COX17 (0.946); TIM13 (0.917); MDM35 (0.913); TIM8 (0.91); COA4 (0.91); CMC2 (0.9); CCS1 (0.9); MIX23 (0.895); COX2 (0.826); YBR056W (0.817); SCO2 (0.806); CMC1 (0.756); COX12 (0.756)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:798386-798700:- | gene-YMR244C-A_AKU4011 | rna-NM_001182751.1_AKU4011 | cds-NP_013972.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:155855-156169:+ | gene-YMR244C-A_BG1 | rna-NM_001182751.1_BG1 | cds-NP_013972.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:742618-742932:- | gene-YMR244C-A_Bruggeman | rna-NM_001182751.1_Bruggeman | cds-NP_013972.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:746542-746856:- | gene-YMR244C-A_CAT1 | rna-NM_001182751.1_CAT1 | cds-NP_013972.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:730646-730960:- | gene-YMR244C-A_CBS1585 | rna-NM_001182751.1_CBS1585 | cds-NP_013972.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:734925-735239:- | gene-YMR244C-A_CBS436 | rna-NM_001182751.1_CBS436 | cds-NP_013972.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:842203-842517:- | gene-YMR244C-A_CBS6412 | rna-NM_001182751.1_CBS6412 | cds-NP_013972.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:729797-730111:- | gene-YMR244C-A_CBS6413 | rna-NM_001182751.1_CBS6413 | cds-NP_013972.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:753248-753562:- | gene-YMR244C-A_CENPK1137D | rna-NM_001182751.1_CENPK1137D | cds-NP_013972.1_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:791046-791360:- | gene-YMR244C-A_EthanolRed | rna-NM_001182751.1_EthanolRed | cds-NP_013972.1_EthanolRed | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:737071-737385:- | gene-YMR244C-A_FaliES1 | rna-NM_001182751.1_FaliES1 | cds-NP_013972.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:49189-49503:+ | gene-YMR244C-A_JAY291 | rna-NM_001182751.1_JAY291 | cds-NP_013972.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:736401-736715:- | gene-YMR244C-A_MUCL30387 | rna-NM_001182751.1_MUCL30387 | cds-NP_013972.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:743624-743938:- | gene-YMR244C-A_MUCL30388 | rna-NM_001182751.1_MUCL30388 | cds-NP_013972.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:731716-732030:- | gene-YMR244C-A_MUCL39482 | rna-NM_001182751.1_MUCL39482 | cds-NP_013972.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:739064-739378:- | gene-YMR244C-A_MUCL42920 | rna-NM_001182751.1_MUCL42920 | cds-NP_013972.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:758471-758785:- | gene-YMR244C-A_NCIM3186 | rna-NM_001182751.1_NCIM3186 | cds-NP_013972.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:731371-731685:- | gene-YMR244C-A_NCYC1407 | rna-NM_001182751.1_NCYC1407 | cds-NP_013972.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:741265-741579:- | gene-YMR244C-A_PE2H3 | rna-NM_001182751.1_PE2H3 | cds-NP_013972.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:742306-742620:- | gene-YMR244C-A_PE2H4 | rna-NM_001182751.1_PE2H4 | cds-NP_013972.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:758517-758831:- | gene-YMR244C-A_S288C | rna-NM_001182751.1_S288C | cds-NP_013972.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:49306-49620:+ | gene-YMR244C-A_SA1 | rna-NM_001182751.1_SA1 | cds-NP_013972.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:733243-733557:- | gene-YMR244C-A_ThermosaccDry | rna-NM_001182751.1_ThermosaccDry | cds-NP_013972.1_ThermosaccDry | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:745798-746112:- | gene-YMR244C-A_VR1 | rna-NM_001182751.1_VR1 | cds-NP_013972.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:148378-148692:- | gene-YMR244C-A_ZTW1 | rna-NM_001182751.1_ZTW1 | cds-NP_013972.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:751070-751384:- | gene-YMR244C-A_Sparadoxus | rna-NM_001182751.1_Sparadoxus | cds-NP_013972.1_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |