Gene name: COA4
Reference locus (S288C): YLR218C
Gene biotype: protein_coding
Description: Cytochrome oxidase assembly factor 4; Twin Cx(9)C protein involved in cytochrome c oxidase organization; organization includes assembly or stability; localizes to the mitochondrial intermembrane space via the Mia40p-Erv1p system; interacts genetically with CYC1 and with cytochrome c oxidase assembly factors; Belongs to the COA4 family
Top 10 interactors (score): MIA40 (0.979); COX17 (0.966); ERV1 (0.955); CMC2 (0.948); TIM10 (0.945); COX19 (0.938); MDM35 (0.933); TIM8 (0.919); TIM13 (0.913); COA6 (0.91); TIM9 (0.91); MIX14 (0.905); MIX17 (0.9); CCS1 (0.9); CMC1 (0.892); SHY1 (0.824); AIM36 (0.813); PUF3 (0.763); COA2 (0.76); QRI5 (0.737)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:527608-528060:- | gene-YLR218C_AKU4011 | rna-NM_001182105.1_AKU4011 | cds-NP_013319.1_AKU4011 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:84865-85317:- | gene-YLR218C_BG1 | rna-NM_001182105.1_BG1 | cds-NP_013319.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:567834-568286:- | gene-YLR218C_Bruggeman | rna-NM_001182105.1_Bruggeman | cds-NP_013319.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:567483-567935:- | gene-YLR218C_CAT1 | rna-NM_001182105.1_CAT1 | cds-NP_013319.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:563100-563552:- | gene-YLR218C_CBS1585 | rna-NM_001182105.1_CBS1585 | cds-NP_013319.1_CBS1585 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:553301-553753:- | gene-YLR218C_CBS436 | rna-NM_001182105.1_CBS436 | cds-NP_013319.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:531662-532114:- | gene-YLR218C_CBS6412 | rna-NM_001182105.1_CBS6412 | cds-NP_013319.1_CBS6412 | 98.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:563397-563849:- | gene-YLR218C_CBS6413 | rna-NM_001182105.1_CBS6413 | cds-NP_013319.1_CBS6413 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:558189-558641:- | gene-YLR218C_CENPK1137D | rna-NM_001182105.1_CENPK1137D | cds-NP_013319.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:527121-527573:- | gene-YLR218C_EthanolRed | rna-NM_001182105.1_EthanolRed | cds-NP_013319.1_EthanolRed | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:556048-556500:- | gene-YLR218C_FaliES1 | rna-NM_001182105.1_FaliES1 | cds-NP_013319.1_FaliES1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:82951-83403:- | gene-YLR218C_JAY291 | rna-NM_001182105.1_JAY291 | cds-NP_013319.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:568695-569147:- | gene-YLR218C_MUCL30387 | rna-NM_001182105.1_MUCL30387 | cds-NP_013319.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:572816-573268:- | gene-YLR218C_MUCL30388 | rna-NM_001182105.1_MUCL30388 | cds-NP_013319.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:564083-564535:- | gene-YLR218C_MUCL39482 | rna-NM_001182105.1_MUCL39482 | cds-NP_013319.1_MUCL39482 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:564582-565034:- | gene-YLR218C_MUCL42920 | rna-NM_001182105.1_MUCL42920 | cds-NP_013319.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:573440-573892:- | gene-YLR218C_NCIM3186 | rna-NM_001182105.1_NCIM3186 | cds-NP_013319.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:556502-556954:- | gene-YLR218C_NCYC1407 | rna-NM_001182105.1_NCYC1407 | cds-NP_013319.1_NCYC1407 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:560754-561206:- | gene-YLR218C_PE2H3 | rna-NM_001182105.1_PE2H3 | cds-NP_013319.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:560498-560950:- | gene-YLR218C_PE2H4 | rna-NM_001182105.1_PE2H4 | cds-NP_013319.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:573466-573918:- | gene-YLR218C_S288C | rna-NM_001182105.1_S288C | cds-NP_013319.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:83002-83454:- | gene-YLR218C_SA1 | rna-NM_001182105.1_SA1 | cds-NP_013319.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:558541-558993:- | gene-YLR218C_ThermosaccDry | rna-NM_001182105.1_ThermosaccDry | cds-NP_013319.1_ThermosaccDry | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:569888-570340:- | gene-YLR218C_VR1 | rna-NM_001182105.1_VR1 | cds-NP_013319.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:82829-83281:- | gene-YLR218C_ZTW1 | rna-NM_001182105.1_ZTW1 | cds-NP_013319.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:544689-545143:- | gene-YLR218C_Sparadoxus | rna-NM_001182105.1_Sparadoxus | cds-NP_013319.1_Sparadoxus | 90.1 | 99.7 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |