Gene name: CNN1
Reference locus (S288C): YFR046C
Gene biotype: protein_coding
Description: Kinetochore-associated protein CNN1; Kinetochore protein; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by Clb5-Cdk1, Mps1p, Ipl1p and to a lesser extent by Clb2-Cdk1; localizes to the lower region of the Ndc80 complex during anaphase and regulates KMN activity by inhibiting the Mtw1 and Spc105 complexes from binding to the Ndc80 complex; similar to metazoan CENP-T
Top 10 interactors (score): WIP1 (0.995); CTF3 (0.988); SPC24 (0.986); MCM22 (0.98); SPC25 (0.975); MCM16 (0.974); DSN1 (0.961); AME1 (0.909); IML3 (0.894); OKP1 (0.878); CHL4 (0.869); CTF19 (0.86); NKP2 (0.859); NKP1 (0.859); NNF1 (0.854); MTW1 (0.823); SPC105 (0.823); MCM21 (0.818); CDC28 (0.782); YMR114C (0.745)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:233224-234309:- | gene-YFR046C_AKU4011 | rna-NM_001180011.1_AKU4011 | cds-NP_116704.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000071.1:26700-27785:+ | gene-YFR046C_BG1 | rna-NM_001180011.1_BG1 | cds-NP_116704.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:236880-237965:- | gene-YFR046C_Bruggeman | rna-NM_001180011.1_Bruggeman | cds-NP_116704.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:238850-239935:- | gene-YFR046C_CAT1 | rna-NM_001180011.1_CAT1 | cds-NP_116704.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:234724-235809:- | gene-YFR046C_CBS1585 | rna-NM_001180011.1_CBS1585 | cds-NP_116704.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:207685-208770:- | gene-YFR046C_CBS436 | rna-NM_001180011.1_CBS436 | cds-NP_116704.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:233799-234884:- | gene-YFR046C_CBS6412 | rna-NM_001180011.1_CBS6412 | cds-NP_116704.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:236472-237557:- | gene-YFR046C_CBS6413 | rna-NM_001180011.1_CBS6413 | cds-NP_116704.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:239163-240248:- | gene-YFR046C_CENPK1137D | rna-NM_001180011.1_CENPK1137D | cds-NP_116704.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:232342-233427:- | gene-YFR046C_EthanolRed | rna-NM_001180011.1_EthanolRed | cds-NP_116704.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:233992-235077:- | gene-YFR046C_FaliES1 | rna-NM_001180011.1_FaliES1 | cds-NP_116704.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000453.1:37123-38208:- | gene-YFR046C_JAY291 | rna-NM_001180011.1_JAY291 | cds-NP_116704.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:237329-238414:- | gene-YFR046C_MUCL30387 | rna-NM_001180011.1_MUCL30387 | cds-NP_116704.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:232808-233893:- | gene-YFR046C_MUCL30388 | rna-NM_001180011.1_MUCL30388 | cds-NP_116704.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:232646-233731:- | gene-YFR046C_MUCL39482 | rna-NM_001180011.1_MUCL39482 | cds-NP_116704.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:232248-233333:- | gene-YFR046C_MUCL42920 | rna-NM_001180011.1_MUCL42920 | cds-NP_116704.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:243073-244158:- | gene-YFR046C_NCIM3186 | rna-NM_001180011.1_NCIM3186 | cds-NP_116704.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:233496-234581:- | gene-YFR046C_NCYC1407 | rna-NM_001180011.1_NCYC1407 | cds-NP_116704.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:275533-276618:- | gene-YFR046C_PE2H3 | rna-NM_001180011.1_PE2H3 | cds-NP_116704.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:275081-276166:- | gene-YFR046C_PE2H4 | rna-NM_001180011.1_PE2H4 | cds-NP_116704.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:243074-244159:- | gene-YFR046C_S288C | rna-NM_001180011.1_S288C | cds-NP_116704.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000086.1:26943-28028:+ | gene-YFR046C_SA1 | rna-NM_001180011.1_SA1 | cds-NP_116704.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:233161-234246:- | gene-YFR046C_ThermosaccDry | rna-NM_001180011.1_ThermosaccDry | cds-NP_116704.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:248915-250000:- | gene-YFR046C_VR1 | rna-NM_001180011.1_VR1 | cds-NP_116704.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:163609-164694:- | gene-YFR046C_ZTW1 | rna-NM_001180011.1_ZTW1 | cds-NP_116704.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:256656-257744:- | gene-YFR046C_Sparadoxus | rna-NM_001180011.1_Sparadoxus | cds-NP_116704.1_Sparadoxus | 85.7 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |