Gene name: CNB1
Reference locus (S288C): YKL190W
Gene biotype: protein_coding
Description: Calcineurin B; regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (stress-response transcription factor); other calcineurin subunit encoded by CNA1 and/or CMP1; regulates function of Aly1p alpha-arrestin; myristoylation by Nmt1p reduces calcineurin activity in response to submaximal Ca signals, is needed to prevent constitutive phosphatase activity; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): CNA1 (0.999); CMP2 (0.999); FPR1 (0.997); CRZ1 (0.988); PMC1 (0.966); CCH1 (0.962); RCN1 (0.958); CDC55 (0.95); SIT4 (0.949); GLC7 (0.943); PPH3 (0.938); CMK2 (0.931); PPH21 (0.928); SDS22 (0.925); FKS1 (0.924); RRD2 (0.917); SLT2 (0.912); TPD3 (0.91); PSY2 (0.909); GAC1 (0.904)
Homologues (species, bitscore): ENSP00000477980 (Homo sapiens, 201.1); Ppp3r1 (Mus musculus, 192.6); ppp3r1b (Danio rerio, 192.6); ppp3r1 (Xenopus tropicalis, 192.6); CanB (Drosophila melanogaster, 186.8); cnb-1 (Caenorhabditis elegans, 193.4); AT3G18430 (Arabidopsis thaliana, 94.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:69308-69911:+ | gene-YKL190W_AKU4011 | rna-NM_001179756.1_AKU4011 | cds-NP_012731.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:46323-46926:+ | gene-YKL190W_BG1 | rna-NM_001179756.1_BG1 | cds-NP_012731.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:87181-87784:+ | gene-YKL190W_Bruggeman | rna-NM_001179756.1_Bruggeman | cds-NP_012731.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:82142-82745:+ | gene-YKL190W_CAT1 | rna-NM_001179756.1_CAT1 | cds-NP_012731.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:81292-81895:+ | gene-YKL190W_CBS1585 | rna-NM_001179756.1_CBS1585 | cds-NP_012731.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:80537-81140:+ | gene-YKL190W_CBS436 | rna-NM_001179756.1_CBS436 | cds-NP_012731.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:66545-67148:+ | gene-YKL190W_CBS6412 | rna-NM_001179756.1_CBS6412 | cds-NP_012731.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:81954-82557:+ | gene-YKL190W_CBS6413 | rna-NM_001179756.1_CBS6413 | cds-NP_012731.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:82776-83379:+ | gene-YKL190W_CENPK1137D | rna-NM_001179756.1_CENPK1137D | cds-NP_012731.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:80570-81173:+ | gene-YKL190W_EthanolRed | rna-NM_001179756.1_EthanolRed | cds-NP_012731.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:80850-81453:+ | gene-YKL190W_FaliES1 | rna-NM_001179756.1_FaliES1 | cds-NP_012731.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000006.2:80369-80972:+ | gene-YKL190W_JAY291 | rna-NM_001179756.1_JAY291 | cds-NP_012731.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:89482-90085:+ | gene-YKL190W_MUCL30387 | rna-NM_001179756.1_MUCL30387 | cds-NP_012731.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:83579-84182:+ | gene-YKL190W_MUCL30388 | rna-NM_001179756.1_MUCL30388 | cds-NP_012731.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:81349-81952:+ | gene-YKL190W_MUCL39482 | rna-NM_001179756.1_MUCL39482 | cds-NP_012731.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:84907-85510:+ | gene-YKL190W_MUCL42920 | rna-NM_001179756.1_MUCL42920 | cds-NP_012731.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:82936-83539:+ | gene-YKL190W_NCIM3186 | rna-NM_001179756.1_NCIM3186 | cds-NP_012731.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:81374-81977:+ | gene-YKL190W_NCYC1407 | rna-NM_001179756.1_NCYC1407 | cds-NP_012731.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:88910-89513:+ | gene-YKL190W_PE2H3 | rna-NM_001179756.1_PE2H3 | cds-NP_012731.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:85204-85807:+ | gene-YKL190W_PE2H4 | rna-NM_001179756.1_PE2H4 | cds-NP_012731.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:82947-83550:+ | gene-YKL190W_S288C | rna-NM_001179756.1_S288C | cds-NP_012731.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000113.1:16824-17427:+ | gene-YKL190W_SA1 | rna-NM_001179756.1_SA1 | cds-NP_012731.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:81552-82155:+ | gene-YKL190W_ThermosaccDry | rna-NM_001179756.1_ThermosaccDry | cds-NP_012731.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:80616-81219:+ | gene-YKL190W_VR1 | rna-NM_001179756.1_VR1 | cds-NP_012731.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:80487-81090:+ | gene-YKL190W_ZTW1 | rna-NM_001179756.1_ZTW1 | cds-NP_012731.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:94747-95350:+ | gene-YKL190W_Sparadoxus | rna-NM_001179756.1_Sparadoxus | cds-NP_012731.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |