Gene name: CNA1
Reference locus (S288C): YLR433C
Gene biotype: protein_coding
Description: Serine/threonine-protein phosphatase 2B catalytic subunit A1; Calcineurin A; one isoform (the other is Cmp2p) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1; regulates the function of Aly1p alpha-arrestin; CNA1 has a paralog, CMP2, that arose from the whole genome duplication
Top 10 interactors (score): CNB1 (0.999); CMD1 (0.999); RCN1 (0.997); FPR1 (0.992); CRZ1 (0.988); CMP2 (0.98); TPD3 (0.95); CDC55 (0.95); RRD2 (0.942); SDS22 (0.939); BCY1 (0.937); GAC1 (0.931); PSY2 (0.929); PPH21 (0.915); GLC7 (0.913); REG1 (0.912); SIT4 (0.911); PPH3 (0.904); PSY4 (0.9); SRV2 (0.889)
Homologues (species, bitscore): PPP3CC (Homo sapiens, 534.3); Ppp3cc (Mus musculus, 528.5); ppp3ca (Danio rerio, 525.0); ppp3ca (Xenopus tropicalis, 529.3); CanA1 (Drosophila melanogaster, 557.0); tax-6 (Caenorhabditis elegans, 551.2); TOPP4 (Arabidopsis thaliana, 212.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:942601-944262:- | gene-YLR433C_AKU4011 | rna-NM_001182321.1_AKU4011 | cds-NP_013537.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000048.1:175054-176715:- | gene-YLR433C_BG1 | rna-NM_001182321.1_BG1 | cds-NP_013537.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:980903-982564:- | gene-YLR433C_Bruggeman | rna-NM_001182321.1_Bruggeman | cds-NP_013537.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:976920-978581:- | gene-YLR433C_CAT1 | rna-NM_001182321.1_CAT1 | cds-NP_013537.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:978198-979859:- | gene-YLR433C_CBS1585 | rna-NM_001182321.1_CBS1585 | cds-NP_013537.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:967543-969204:- | gene-YLR433C_CBS436 | rna-NM_001182321.1_CBS436 | cds-NP_013537.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:1014238-1015899:- | gene-YLR433C_CBS6412 | rna-NM_001182321.1_CBS6412 | cds-NP_013537.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:978983-980644:- | gene-YLR433C_CBS6413 | rna-NM_001182321.1_CBS6413 | cds-NP_013537.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:988964-990625:- | gene-YLR433C_CENPK1137D | rna-NM_001182321.1_CENPK1137D | cds-NP_013537.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:935629-937290:- | gene-YLR433C_EthanolRed | rna-NM_001182321.1_EthanolRed | cds-NP_013537.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:970900-972561:- | gene-YLR433C_FaliES1 | rna-NM_001182321.1_FaliES1 | cds-NP_013537.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000194.1:46130-47791:+ | gene-YLR433C_JAY291 | rna-NM_001182321.1_JAY291 | cds-NP_013537.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:979764-981425:- | gene-YLR433C_MUCL30387 | rna-NM_001182321.1_MUCL30387 | cds-NP_013537.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:987122-988783:- | gene-YLR433C_MUCL30388 | rna-NM_001182321.1_MUCL30388 | cds-NP_013537.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:979418-981079:- | gene-YLR433C_MUCL39482 | rna-NM_001182321.1_MUCL39482 | cds-NP_013537.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:979913-981574:- | gene-YLR433C_MUCL42920 | rna-NM_001182321.1_MUCL42920 | cds-NP_013537.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:1004321-1005982:- | gene-YLR433C_NCIM3186 | rna-NM_001182321.1_NCIM3186 | cds-NP_013537.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:988846-990507:- | gene-YLR433C_NCYC1407 | rna-NM_001182321.1_NCYC1407 | cds-NP_013537.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:975294-976955:- | gene-YLR433C_PE2H3 | rna-NM_001182321.1_PE2H3 | cds-NP_013537.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:975038-976699:- | gene-YLR433C_PE2H4 | rna-NM_001182321.1_PE2H4 | cds-NP_013537.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:1004347-1006008:- | gene-YLR433C_S288C | rna-NM_001182321.1_S288C | cds-NP_013537.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000007.1:53954-55615:+ | gene-YLR433C_SA1 | rna-NM_001182321.1_SA1 | cds-NP_013537.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:973979-975640:- | gene-YLR433C_ThermosaccDry | rna-NM_001182321.1_ThermosaccDry | cds-NP_013537.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:980399-982060:- | gene-YLR433C_VR1 | rna-NM_001182321.1_VR1 | cds-NP_013537.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:304251-305912:- | gene-YLR433C_ZTW1 | rna-NM_001182321.1_ZTW1 | cds-NP_013537.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:953397-955058:- | gene-YLR433C_Sparadoxus | rna-NM_001182321.1_Sparadoxus | cds-NP_013537.1_Sparadoxus | 91.2 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |