Gene name: CMR1
Reference locus (S288C): YDL156W
Gene biotype: protein_coding
Description: DNA damage-binding protein CMR1; Nuclear protein with a role in protein quality control; localizes to the intranuclear quality control compartment (INQ) in response to proteasome inhibition or DNA replication stress; INQ likely sequesters proteins involved in DNA metabolism for degradation or re-folding; DNA-binding protein with preference for UV-damaged DNA; contains three WD domains (WD-40 repeat); human ortholog WDR76 also exhibits perinuclear localization under similar stress conditions
Top 10 interactors (score): RFA1 (0.921); RFA2 (0.893); MSH6 (0.863); RAD4 (0.833); RFA3 (0.814); YKU80 (0.813); RAD52 (0.806); IRC5 (0.799); HRT1 (0.798); YKU70 (0.777); RAD34 (0.766); RAD27 (0.764); ABF2 (0.761); CDC53 (0.761); EXO5 (0.753); HOS2 (0.739); TCP1 (0.735); RRI1 (0.731); APJ1 (0.715); HHF1 (0.715)
Homologues (species, bitscore): WDR76 (Homo sapiens, 114.0); Wdr76 (Mus musculus, 122.1); wdr76 (Danio rerio, 94.4); wdr76 (Xenopus tropicalis, 112.1); DRS1 (Arabidopsis thaliana, 127.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:159336-160904:+ | gene-YDL156W_AKU4011 | rna-NM_001180216.1_AKU4011 | cds-NP_010125.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:388874-390442:- | gene-YDL156W_BG1 | rna-NM_001180216.1_BG1 | cds-NP_010125.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:175384-176952:+ | gene-YDL156W_Bruggeman | rna-NM_001180216.1_Bruggeman | cds-NP_010125.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:173703-175271:+ | gene-YDL156W_CAT1 | rna-NM_001180216.1_CAT1 | cds-NP_010125.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:157367-158935:+ | gene-YDL156W_CBS1585 | rna-NM_001180216.1_CBS1585 | cds-NP_010125.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:174309-175877:+ | gene-YDL156W_CBS436 | rna-NM_001180216.1_CBS436 | cds-NP_010125.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:156620-158188:+ | gene-YDL156W_CBS6412 | rna-NM_001180216.1_CBS6412 | cds-NP_010125.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:175805-177373:+ | gene-YDL156W_CBS6413 | rna-NM_001180216.1_CBS6413 | cds-NP_010125.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:173570-175138:+ | gene-YDL156W_CENPK1137D | rna-NM_001180216.1_CENPK1137D | cds-NP_010125.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:170575-172143:+ | gene-YDL156W_EthanolRed | rna-NM_001180216.1_EthanolRed | cds-NP_010125.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:176107-177675:+ | gene-YDL156W_FaliES1 | rna-NM_001180216.1_FaliES1 | cds-NP_010125.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:41874-43442:- | gene-YDL156W_JAY291 | rna-NM_001180216.1_JAY291 | cds-NP_010125.1_JAY291 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:174498-176066:+ | gene-YDL156W_MUCL30387 | rna-NM_001180216.1_MUCL30387 | cds-NP_010125.1_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:165359-166927:+ | gene-YDL156W_MUCL30388 | rna-NM_001180216.1_MUCL30388 | cds-NP_010125.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:158522-160090:+ | gene-YDL156W_MUCL39482 | rna-NM_001180216.1_MUCL39482 | cds-NP_010125.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000307.1:9300-10868:- | gene-YDL156W_MUCL42920 | rna-NM_001180216.1_MUCL42920 | cds-NP_010125.1_MUCL42920 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:174841-176409:+ | gene-YDL156W_NCIM3186 | rna-NM_001180216.1_NCIM3186 | cds-NP_010125.1_NCIM3186 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:158455-160023:+ | gene-YDL156W_NCYC1407 | rna-NM_001180216.1_NCYC1407 | cds-NP_010125.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:165696-167264:+ | gene-YDL156W_PE2H3 | rna-NM_001180216.1_PE2H3 | cds-NP_010125.1_PE2H3 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:165700-167268:+ | gene-YDL156W_PE2H4 | rna-NM_001180216.1_PE2H4 | cds-NP_010125.1_PE2H4 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:174918-176486:+ | gene-YDL156W_S288C | rna-NM_001180216.1_S288C | cds-NP_010125.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:40480-42048:+ | gene-YDL156W_SA1 | rna-NM_001180216.1_SA1 | cds-NP_010125.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:175868-177436:+ | gene-YDL156W_ThermosaccDry | rna-NM_001180216.1_ThermosaccDry | cds-NP_010125.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:176466-178034:+ | gene-YDL156W_VR1 | rna-NM_001180216.1_VR1 | cds-NP_010125.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:173995-175563:+ | gene-YDL156W_ZTW1 | rna-NM_001180216.1_ZTW1 | cds-NP_010125.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:176132-177699:+ | gene-YDL156W_Sparadoxus | rna-NM_001180216.1_Sparadoxus | cds-NP_010125.1_Sparadoxus | 90.4 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |