Gene name: CMP2
Reference locus (S288C): YML057W
Gene biotype: protein_coding
Description: Serine/threonine-protein phosphatase 2B catalytic subunit A2; Calcineurin A; one isoform (the other is Cna1p) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1; regulates the function of Aly1p alpha-arrestin; CMP2 has a paralog, CNA1, that arose from the whole genome duplication
Top 10 interactors (score): CMD1 (0.999); CNB1 (0.999); RCN1 (0.996); FPR1 (0.986); CNA1 (0.98); CRZ1 (0.967); CDC55 (0.953); TPD3 (0.952); RRD2 (0.944); SDS22 (0.939); PSY2 (0.934); GAC1 (0.931); BCY1 (0.93); PPH21 (0.918); GLC7 (0.912); SIT4 (0.912); REG1 (0.912); PPH3 (0.906); PSY4 (0.903); SRV2 (0.897)
Homologues (species, bitscore): PPP3CA (Homo sapiens, 547.0); Ppp3ca (Mus musculus, 546.2); ppp3ca (Danio rerio, 535.0); ppp3ca (Xenopus tropicalis, 542.3); CanA1 (Drosophila melanogaster, 563.1); tax-6 (Caenorhabditis elegans, 544.7); TOPP4 (Arabidopsis thaliana, 221.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:153910-155724:+ | gene-YML057W_AKU4011 | rna-NM_001182415.1_AKU4011 | cds-NP_013655.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:320445-322259:- | gene-YML057W_BG1 | rna-NM_001182415.1_BG1 | cds-NP_013655.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:160045-161859:+ | gene-YML057W_Bruggeman | rna-NM_001182415.1_Bruggeman | cds-NP_013655.1_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:161720-163534:+ | gene-YML057W_CAT1 | rna-NM_001182415.1_CAT1 | cds-NP_013655.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:153921-155735:+ | gene-YML057W_CBS1585 | rna-NM_001182415.1_CBS1585 | cds-NP_013655.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:159816-161630:+ | gene-YML057W_CBS436 | rna-NM_001182415.1_CBS436 | cds-NP_013655.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:154629-156443:+ | gene-YML057W_CBS6412 | rna-NM_001182415.1_CBS6412 | cds-NP_013655.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:153103-154917:+ | gene-YML057W_CBS6413 | rna-NM_001182415.1_CBS6413 | cds-NP_013655.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:154885-156699:+ | gene-YML057W_CENPK1137D | rna-NM_001182415.1_CENPK1137D | cds-NP_013655.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:154194-156008:+ | gene-YML057W_EthanolRed | rna-NM_001182415.1_EthanolRed | cds-NP_013655.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:154699-156513:+ | gene-YML057W_FaliES1 | rna-NM_001182415.1_FaliES1 | cds-NP_013655.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000366.1:614-2428:- | gene-YML057W_JAY291 | rna-NM_001182415.1_JAY291 | cds-NP_013655.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:158564-160378:+ | gene-YML057W_MUCL30387 | rna-NM_001182415.1_MUCL30387 | cds-NP_013655.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:161752-163566:+ | gene-YML057W_MUCL30388 | rna-NM_001182415.1_MUCL30388 | cds-NP_013655.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:153931-155745:+ | gene-YML057W_MUCL39482 | rna-NM_001182415.1_MUCL39482 | cds-NP_013655.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:159749-161563:+ | gene-YML057W_MUCL42920 | rna-NM_001182415.1_MUCL42920 | cds-NP_013655.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:160134-161948:+ | gene-YML057W_NCIM3186 | rna-NM_001182415.1_NCIM3186 | cds-NP_013655.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:154724-156538:+ | gene-YML057W_NCYC1407 | rna-NM_001182415.1_NCYC1407 | cds-NP_013655.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:160127-161941:+ | gene-YML057W_PE2H3 | rna-NM_001182415.1_PE2H3 | cds-NP_013655.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:159991-161805:+ | gene-YML057W_PE2H4 | rna-NM_001182415.1_PE2H4 | cds-NP_013655.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:160180-161994:+ | gene-YML057W_S288C | rna-NM_001182415.1_S288C | cds-NP_013655.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000041.1:22231-24045:- | gene-YML057W_SA1 | rna-NM_001182415.1_SA1 | cds-NP_013655.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:153992-155806:+ | gene-YML057W_ThermosaccDry | rna-NM_001182415.1_ThermosaccDry | cds-NP_013655.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:158340-160154:+ | gene-YML057W_VR1 | rna-NM_001182415.1_VR1 | cds-NP_013655.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:133515-135329:+ | gene-YML057W_ZTW1 | rna-NM_001182415.1_ZTW1 | cds-NP_013655.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:165157-166971:+ | gene-YML057W_Sparadoxus | rna-NM_001182415.1_Sparadoxus | cds-NP_013655.1_Sparadoxus | 91.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |