CMK2 (YOL016C)


Gene profile

Gene name: CMK2
Reference locus (S288C): YOL016C
Gene biotype: protein_coding

Description: Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily

Top 10 interactors (score): CMD1 (0.994); RCN2 (0.973); DIA1 (0.958); CNB1 (0.931); YOR385W (0.928); GYP7 (0.913); CMP2 (0.885); CNA1 (0.885); CRZ1 (0.87); MNC1 (0.857); PMC1 (0.785); PMR1 (0.77); RCR1 (0.746); PUN1 (0.736); EDE1 (0.72); TOS3 (0.705); VCX1 (0.69); SAK1 (0.681); PKP2 (0.67); NCW2 (0.66)

Homologues (species, bitscore): CAMK1D (Homo sapiens, 233.8); Camk1d (Mus musculus, 237.3); camk1db (Danio rerio, 242.7); camk1 (Xenopus tropicalis, 236.5); CaMKI (Drosophila melanogaster, 218.8); cmk-1 (Caenorhabditis elegans, 225.7); CPK24 (Arabidopsis thaliana, 194.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:279163-280506:- gene-YOL016C_AKU4011 rna-NM_001183270.1_AKU4011 cds-NP_014626.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:94750-96093:- gene-YOL016C_BG1 rna-NM_001183270.1_BG1 cds-NP_014626.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:281990-283333:- gene-YOL016C_Bruggeman rna-NM_001183270.1_Bruggeman cds-NP_014626.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:279862-281205:- gene-YOL016C_CAT1 rna-NM_001183270.1_CAT1 cds-NP_014626.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:273840-275183:- gene-YOL016C_CBS1585 rna-NM_001183270.1_CBS1585 cds-NP_014626.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:278080-279423:- gene-YOL016C_CBS436 rna-NM_001183270.1_CBS436 cds-NP_014626.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:273197-274540:- gene-YOL016C_CBS6412 rna-NM_001183270.1_CBS6412 cds-NP_014626.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:280724-282067:- gene-YOL016C_CBS6413 rna-NM_001183270.1_CBS6413 cds-NP_014626.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:294474-295817:- gene-YOL016C_CENPK1137D rna-NM_001183270.1_CENPK1137D cds-NP_014626.1_CENPK1137D 99.6 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:275992-277335:- gene-YOL016C_EthanolRed rna-NM_001183270.1_EthanolRed cds-NP_014626.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:279319-280662:- gene-YOL016C_FaliES1 rna-NM_001183270.1_FaliES1 cds-NP_014626.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000131.1:6578-7921:- gene-YOL016C_JAY291 rna-NM_001183270.1_JAY291 cds-NP_014626.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:286169-287512:- gene-YOL016C_MUCL30387 rna-NM_001183270.1_MUCL30387 cds-NP_014626.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:289365-290708:- gene-YOL016C_MUCL30388 rna-NM_001183270.1_MUCL30388 cds-NP_014626.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:281325-282668:- gene-YOL016C_MUCL39482 rna-NM_001183270.1_MUCL39482 cds-NP_014626.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:296247-297590:- gene-YOL016C_MUCL42920 rna-NM_001183270.1_MUCL42920 cds-NP_014626.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:294666-296009:- gene-YOL016C_NCIM3186 rna-NM_001183270.1_NCIM3186 cds-NP_014626.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:288058-289401:- gene-YOL016C_NCYC1407 rna-NM_001183270.1_NCYC1407 cds-NP_014626.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:270444-271787:- gene-YOL016C_PE2H3 rna-NM_001183270.1_PE2H3 cds-NP_014626.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:281418-282761:- gene-YOL016C_PE2H4 rna-NM_001183270.1_PE2H4 cds-NP_014626.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:294777-296120:- gene-YOL016C_S288C rna-NM_001183270.1_S288C cds-NP_014626.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:262770-264113:- gene-YOL016C_SA1 rna-NM_001183270.1_SA1 cds-NP_014626.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:277890-279233:- gene-YOL016C_ThermosaccDry rna-NM_001183270.1_ThermosaccDry cds-NP_014626.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:277927-279270:- gene-YOL016C_VR1 rna-NM_001183270.1_VR1 cds-NP_014626.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:12539-13882:- gene-YOL016C_ZTW1 rna-NM_001183270.1_ZTW1 cds-NP_014626.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:285933-287276:- gene-YOL016C_Sparadoxus rna-NM_001183270.1_Sparadoxus cds-NP_014626.1_Sparadoxus 92.6 100.0 Unannotated 1 1 0 False False False False True

Additional files