CMK1 (YFR014C)


Gene profile

Gene name: CMK1
Reference locus (S288C): YFR014C
Gene biotype: protein_coding

Description: Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily

Top 10 interactors (score): CMD1 (0.989); CNA1 (0.885); CMP2 (0.885); CNB1 (0.867); CKA1 (0.798); TOS3 (0.709); SAK1 (0.686); SEC4 (0.653); DCS1 (0.639); BMH1 (0.639); BMH2 (0.635); MCM1 (0.6); ELM1 (0.582); MAF1 (0.575); PMR1 (0.569); FRQ1 (0.565); KSS1 (0.522); SMP1 (0.51); HDA1 (0.506); PDR12 (0.503)

Homologues (species, bitscore): CAMK1D (Homo sapiens, 238.8); Camk1d (Mus musculus, 238.8); camk1da (Danio rerio, 246.5); camk1 (Xenopus tropicalis, 236.1); CaMKI (Drosophila melanogaster, 238.4); cmk-1 (Caenorhabditis elegans, 235.3); CPK17 (Arabidopsis thaliana, 196.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:162947-164287:- gene-YFR014C_AKU4011 rna-NM_001179979.2_AKU4011 cds-NP_116669.1_AKU4011 99.5 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000071.1:96552-97892:+ gene-YFR014C_BG1 rna-NM_001179979.2_BG1 cds-NP_116669.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:163366-164706:- gene-YFR014C_Bruggeman rna-NM_001179979.2_Bruggeman cds-NP_116669.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:168278-169618:- gene-YFR014C_CAT1 rna-NM_001179979.2_CAT1 cds-NP_116669.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:163771-165111:- gene-YFR014C_CBS1585 rna-NM_001179979.2_CBS1585 cds-NP_116669.1_CBS1585 99.5 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:137613-138953:- gene-YFR014C_CBS436 rna-NM_001179979.2_CBS436 cds-NP_116669.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:163511-164851:- gene-YFR014C_CBS6412 rna-NM_001179979.2_CBS6412 cds-NP_116669.1_CBS6412 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:166024-167364:- gene-YFR014C_CBS6413 rna-NM_001179979.2_CBS6413 cds-NP_116669.1_CBS6413 99.5 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:168635-169975:- gene-YFR014C_CENPK1137D rna-NM_001179979.2_CENPK1137D cds-NP_116669.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:161942-163282:- gene-YFR014C_EthanolRed rna-NM_001179979.2_EthanolRed cds-NP_116669.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:163589-164929:- gene-YFR014C_FaliES1 rna-NM_001179979.2_FaliES1 cds-NP_116669.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000452.1:10428-11768:- gene-YFR014C_JAY291 rna-NM_001179979.2_JAY291 cds-NP_116669.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:165317-166657:- gene-YFR014C_MUCL30387 rna-NM_001179979.2_MUCL30387 cds-NP_116669.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:162124-163464:- gene-YFR014C_MUCL30388 rna-NM_001179979.2_MUCL30388 cds-NP_116669.1_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:162214-163554:- gene-YFR014C_MUCL39482 rna-NM_001179979.2_MUCL39482 cds-NP_116669.1_MUCL39482 99.5 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:161480-162820:- gene-YFR014C_MUCL42920 rna-NM_001179979.2_MUCL42920 cds-NP_116669.1_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:172536-173876:- gene-YFR014C_NCIM3186 rna-NM_001179979.2_NCIM3186 cds-NP_116669.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:163232-164572:- gene-YFR014C_NCYC1407 rna-NM_001179979.2_NCYC1407 cds-NP_116669.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:182307-183647:- gene-YFR014C_PE2H3 rna-NM_001179979.2_PE2H3 cds-NP_116669.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:181855-183195:- gene-YFR014C_PE2H4 rna-NM_001179979.2_PE2H4 cds-NP_116669.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:172537-173877:- gene-YFR014C_S288C rna-NM_001179979.2_S288C cds-NP_116669.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:150372-151712:+ gene-YFR014C_SA1 rna-NM_001179979.2_SA1 cds-NP_116669.1_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:162747-164087:- gene-YFR014C_ThermosaccDry rna-NM_001179979.2_ThermosaccDry cds-NP_116669.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:178204-179544:- gene-YFR014C_VR1 rna-NM_001179979.2_VR1 cds-NP_116669.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:93188-94528:- gene-YFR014C_ZTW1 rna-NM_001179979.2_ZTW1 cds-NP_116669.1_ZTW1 99.6 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:187120-188460:- gene-YFR014C_Sparadoxus rna-NM_001179979.2_Sparadoxus cds-NP_116669.1_Sparadoxus 89.7 99.9 Unannotated 1 1 0 False False False False True

Additional files