Gene name: CMD1
Reference locus (S288C): YBR109C
Gene biotype: protein_coding
Description: Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability
Top 10 interactors (score): CNA1 (0.999); MYO2 (0.999); CMP2 (0.999); MYO5 (0.999); SPC110 (0.999); ACT1 (0.999); CCH1 (0.997); MYO4 (0.997); IQG1 (0.997); MYO3 (0.995); CMK2 (0.994); CMK1 (0.989); TUB2 (0.985); CRZ1 (0.982); CDC42 (0.977); HSC82 (0.97); MYO1 (0.966); PMC1 (0.962); HSP82 (0.952); TOS3 (0.936)
Homologues (species, bitscore): CALM2 (Homo sapiens, 195.7); Calm3 (Mus musculus, 195.7); Calm2b (Danio rerio, 195.7); Calm1 (Xenopus tropicalis, 195.7); Cam (Drosophila melanogaster, 196.4); cmd-1 (Caenorhabditis elegans, 196.4); CAM7 (Arabidopsis thaliana, 187.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:440300-440743:- | gene-YBR109C_AKU4011 | rna-NM_001178457.1_AKU4011 | cds-NP_009667.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:431343-431786:- | gene-YBR109C_BG1 | rna-NM_001178457.1_BG1 | cds-NP_009667.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:442028-442471:- | gene-YBR109C_Bruggeman | rna-NM_001178457.1_Bruggeman | cds-NP_009667.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:444820-445263:- | gene-YBR109C_CAT1 | rna-NM_001178457.1_CAT1 | cds-NP_009667.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:432583-433026:- | gene-YBR109C_CBS1585 | rna-NM_001178457.1_CBS1585 | cds-NP_009667.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:440676-441119:- | gene-YBR109C_CBS436 | rna-NM_001178457.1_CBS436 | cds-NP_009667.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:530812-531255:- | gene-YBR109C_CBS6412 | rna-NM_001178457.1_CBS6412 | cds-NP_009667.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:437724-438167:- | gene-YBR109C_CBS6413 | rna-NM_001178457.1_CBS6413 | cds-NP_009667.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:449817-450260:- | gene-YBR109C_CENPK1137D | rna-NM_001178457.1_CENPK1137D | cds-NP_009667.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:567071-567514:- | gene-YBR109C_EthanolRed | rna-NM_001178457.1_EthanolRed | cds-NP_009667.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:456354-456797:- | gene-YBR109C_FaliES1 | rna-NM_001178457.1_FaliES1 | cds-NP_009667.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000312.1:27272-27715:- | gene-YBR109C_JAY291 | rna-NM_001178457.1_JAY291 | cds-NP_009667.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:444738-445181:- | gene-YBR109C_MUCL30387 | rna-NM_001178457.1_MUCL30387 | cds-NP_009667.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:443082-443525:- | gene-YBR109C_MUCL30388 | rna-NM_001178457.1_MUCL30388 | cds-NP_009667.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:430726-431169:- | gene-YBR109C_MUCL39482 | rna-NM_001178457.1_MUCL39482 | cds-NP_009667.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:440380-440823:- | gene-YBR109C_MUCL42920 | rna-NM_001178457.1_MUCL42920 | cds-NP_009667.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:457716-458159:- | gene-YBR109C_NCIM3186 | rna-NM_001178457.1_NCIM3186 | cds-NP_009667.1_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:433507-433950:- | gene-YBR109C_NCYC1407 | rna-NM_001178457.1_NCYC1407 | cds-NP_009667.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:446117-446560:- | gene-YBR109C_PE2H3 | rna-NM_001178457.1_PE2H3 | cds-NP_009667.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:443793-444236:- | gene-YBR109C_PE2H4 | rna-NM_001178457.1_PE2H4 | cds-NP_009667.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:457919-458362:- | gene-YBR109C_S288C | rna-NM_001178457.1_S288C | cds-NP_009667.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000017.1:19361-19804:+ | gene-YBR109C_SA1 | rna-NM_001178457.1_SA1 | cds-NP_009667.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:455361-455804:- | gene-YBR109C_ThermosaccDry | rna-NM_001178457.1_ThermosaccDry | cds-NP_009667.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:437377-437820:- | gene-YBR109C_VR1 | rna-NM_001178457.1_VR1 | cds-NP_009667.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:431019-431462:- | gene-YBR109C_ZTW1 | rna-NM_001178457.1_ZTW1 | cds-NP_009667.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:467986-468429:- | gene-YBR109C_Sparadoxus | rna-NM_001178457.1_Sparadoxus | cds-NP_009667.1_Sparadoxus | 94.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |