CLP1 (YOR250C)


Gene profile

Gene name: CLP1
Reference locus (S288C): YOR250C
Gene biotype: protein_coding

Description: Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation and in gene looping which affects reinitiation of transcription

Top 10 interactors (score): PCF11 (0.999); RNA15 (0.999); RNA14 (0.999); YTH1 (0.998); YSH1 (0.995); CFT1 (0.992); FIP1 (0.991); CFT2 (0.979); SSU72 (0.976); SYC1 (0.975); PTA1 (0.961); MPE1 (0.947); HRP1 (0.938); TFC4 (0.918); SWD2 (0.916); REF2 (0.91); PFS2 (0.895); PAP1 (0.886); PTI1 (0.885); GLC7 (0.853)

Homologues (species, bitscore): CLP1 (Homo sapiens, 127.9); Clp1 (Mus musculus, 128.6); LOC565621 (Danio rerio, 135.6); clp1 (Xenopus tropicalis, 122.9); cbc (Drosophila melanogaster, 126.3); clpf-1 (Caenorhabditis elegans, 132.5); CLPS3 (Arabidopsis thaliana, 155.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:791741-793078:- gene-YOR250C_AKU4011 rna-NM_001183669.1_AKU4011 cds-NP_014893.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:193784-195121:- gene-YOR250C_BG1 rna-NM_001183669.1_BG1 cds-NP_014893.1_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:777209-778546:- gene-YOR250C_Bruggeman rna-NM_001183669.1_Bruggeman cds-NP_014893.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:777862-779199:- gene-YOR250C_CAT1 rna-NM_001183669.1_CAT1 cds-NP_014893.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:774730-776067:- gene-YOR250C_CBS1585 rna-NM_001183669.1_CBS1585 cds-NP_014893.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:773427-774764:- gene-YOR250C_CBS436 rna-NM_001183669.1_CBS436 cds-NP_014893.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:771849-773186:- gene-YOR250C_CBS6412 rna-NM_001183669.1_CBS6412 cds-NP_014893.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:780489-781826:- gene-YOR250C_CBS6413 rna-NM_001183669.1_CBS6413 cds-NP_014893.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:800734-802071:- gene-YOR250C_CENPK1137D rna-NM_001183669.1_CENPK1137D cds-NP_014893.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:767858-769195:- gene-YOR250C_EthanolRed rna-NM_001183669.1_EthanolRed cds-NP_014893.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:773257-774594:- gene-YOR250C_FaliES1 rna-NM_001183669.1_FaliES1 cds-NP_014893.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:52233-53570:+ gene-YOR250C_JAY291 rna-NM_001183669.1_JAY291 cds-NP_014893.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:781482-782819:- gene-YOR250C_MUCL30387 rna-NM_001183669.1_MUCL30387 cds-NP_014893.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:788598-789935:- gene-YOR250C_MUCL30388 rna-NM_001183669.1_MUCL30388 cds-NP_014893.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:782060-783397:- gene-YOR250C_MUCL39482 rna-NM_001183669.1_MUCL39482 cds-NP_014893.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:791650-792987:- gene-YOR250C_MUCL42920 rna-NM_001183669.1_MUCL42920 cds-NP_014893.1_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:800859-802196:- gene-YOR250C_NCIM3186 rna-NM_001183669.1_NCIM3186 cds-NP_014893.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:782159-783496:- gene-YOR250C_NCYC1407 rna-NM_001183669.1_NCYC1407 cds-NP_014893.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:781465-782802:- gene-YOR250C_PE2H3 rna-NM_001183669.1_PE2H3 cds-NP_014893.1_PE2H3 99.9 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:791842-793179:- gene-YOR250C_PE2H4 rna-NM_001183669.1_PE2H4 cds-NP_014893.1_PE2H4 99.9 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:800970-802307:- gene-YOR250C_S288C rna-NM_001183669.1_S288C cds-NP_014893.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:210966-212303:- gene-YOR250C_SA1 rna-NM_001183669.1_SA1 cds-NP_014893.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:772440-773777:- gene-YOR250C_ThermosaccDry rna-NM_001183669.1_ThermosaccDry cds-NP_014893.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:835905-837242:- gene-YOR250C_VR1 rna-NM_001183669.1_VR1 cds-NP_014893.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:505356-506693:- gene-YOR250C_ZTW1 rna-NM_001183669.1_ZTW1 cds-NP_014893.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:778217-779554:- gene-YOR250C_Sparadoxus rna-NM_001183669.1_Sparadoxus cds-NP_014893.1_Sparadoxus 90.5 100.0 Verified 1 1 1 False True False False False

Additional files