Gene name: CLN1
Reference locus (S288C): YMR199W
Gene biotype: protein_coding
Description: G1/S-specific cyclin CLN1; G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p); CLN1 has a paralog, CLN2, that arose from the whole genome duplication; cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2, CCNB1, CCNC, CCND1, or CCNE1
Top 10 interactors (score): CDC28 (0.999); CLN2 (0.991); CKS1 (0.976); SIC1 (0.967); GRR1 (0.962); SWI6 (0.96); FAR1 (0.96); WHI5 (0.926); SKP1 (0.893); YOX1 (0.887); CDC53 (0.879); SWE1 (0.866); CLN3 (0.857); SWI4 (0.844); PHO85 (0.838); HRT1 (0.827); PCL1 (0.816); CLB2 (0.795); MBP1 (0.778); CLB6 (0.707)
Homologues (species, bitscore): CCNA2 (Homo sapiens, 50.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:702557-704197:+ | gene-YMR199W_AKU4011 | rna-NM_001182706.1_AKU4011 | cds-NP_013926.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:250384-252024:- | gene-YMR199W_BG1 | rna-NM_001182706.1_BG1 | cds-NP_013926.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:646784-648424:+ | gene-YMR199W_Bruggeman | rna-NM_001182706.1_Bruggeman | cds-NP_013926.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:650035-651675:+ | gene-YMR199W_CAT1 | rna-NM_001182706.1_CAT1 | cds-NP_013926.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:634814-636454:+ | gene-YMR199W_CBS1585 | rna-NM_001182706.1_CBS1585 | cds-NP_013926.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:639082-640722:+ | gene-YMR199W_CBS436 | rna-NM_001182706.1_CBS436 | cds-NP_013926.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:746372-748012:+ | gene-YMR199W_CBS6412 | rna-NM_001182706.1_CBS6412 | cds-NP_013926.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:633964-635604:+ | gene-YMR199W_CBS6413 | rna-NM_001182706.1_CBS6413 | cds-NP_013926.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:657333-658973:+ | gene-YMR199W_CENPK1137D | rna-NM_001182706.1_CENPK1137D | cds-NP_013926.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:695005-696645:+ | gene-YMR199W_EthanolRed | rna-NM_001182706.1_EthanolRed | cds-NP_013926.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:640660-642300:+ | gene-YMR199W_FaliES1 | rna-NM_001182706.1_FaliES1 | cds-NP_013926.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000141.1:143701-145341:- | gene-YMR199W_JAY291 | rna-NM_001182706.1_JAY291 | cds-NP_013926.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:640331-641971:+ | gene-YMR199W_MUCL30387 | rna-NM_001182706.1_MUCL30387 | cds-NP_013926.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:647106-648746:+ | gene-YMR199W_MUCL30388 | rna-NM_001182706.1_MUCL30388 | cds-NP_013926.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:635886-637526:+ | gene-YMR199W_MUCL39482 | rna-NM_001182706.1_MUCL39482 | cds-NP_013926.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:643226-644866:+ | gene-YMR199W_MUCL42920 | rna-NM_001182706.1_MUCL42920 | cds-NP_013926.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:662598-664238:+ | gene-YMR199W_NCIM3186 | rna-NM_001182706.1_NCIM3186 | cds-NP_013926.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:635537-637177:+ | gene-YMR199W_NCYC1407 | rna-NM_001182706.1_NCYC1407 | cds-NP_013926.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:645395-647035:+ | gene-YMR199W_PE2H3 | rna-NM_001182706.1_PE2H3 | cds-NP_013926.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:646415-648055:+ | gene-YMR199W_PE2H4 | rna-NM_001182706.1_PE2H4 | cds-NP_013926.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:662644-664284:+ | gene-YMR199W_S288C | rna-NM_001182706.1_S288C | cds-NP_013926.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:143828-145468:- | gene-YMR199W_SA1 | rna-NM_001182706.1_SA1 | cds-NP_013926.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:636786-638426:+ | gene-YMR199W_ThermosaccDry | rna-NM_001182706.1_ThermosaccDry | cds-NP_013926.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:649928-651568:+ | gene-YMR199W_VR1 | rna-NM_001182706.1_VR1 | cds-NP_013926.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:52564-54204:+ | gene-YMR199W_ZTW1 | rna-NM_001182706.1_ZTW1 | cds-NP_013926.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:654704-656344:+ | gene-YMR199W_Sparadoxus | rna-NM_001182706.1_Sparadoxus | cds-NP_013926.1_Sparadoxus | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |