CLB6 (YGR109C)


Gene profile

Gene name: CLB6
Reference locus (S288C): YGR109C
Gene biotype: protein_coding

Description: S-phase entry cyclin-6; B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1; CLB6 has a paralog, CLB5, that arose from the whole genome duplication

Top 10 interactors (score): CDC28 (0.999); CDC6 (0.993); SIC1 (0.988); CLB5 (0.985); MIH1 (0.965); KIN28 (0.964); CCL1 (0.96); SWE1 (0.943); TFB3 (0.939); CDC20 (0.921); CLN2 (0.875); YOX1 (0.874); SWI6 (0.864); MBP1 (0.862); SWI4 (0.862); CKS1 (0.832); APC1 (0.829); MCD1 (0.827); PHO85 (0.809); CDC27 (0.779)

Homologues (species, bitscore): CCNB1 (Homo sapiens, 157.5); Ccnb2 (Mus musculus, 153.3); ccnb2 (Danio rerio, 160.6); ccnb2 (Xenopus tropicalis, 157.9); CycB (Drosophila melanogaster, 141.4); cyb-1 (Caenorhabditis elegans, 110.5); CYCA2;1 (Arabidopsis thaliana, 151.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:690031-691173:- gene-YGR109C_AKU4011 rna-NM_001181238.3_AKU4011 cds-NP_011623.3_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000173.1:125385-126527:- gene-YGR109C_BG1 rna-NM_001181238.3_BG1 cds-NP_011623.3_BG1 99.9 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:691714-692856:- gene-YGR109C_Bruggeman rna-NM_001181238.3_Bruggeman cds-NP_011623.3_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:689918-691060:- gene-YGR109C_CAT1 rna-NM_001181238.3_CAT1 cds-NP_011623.3_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:691021-692163:- gene-YGR109C_CBS1585 rna-NM_001181238.3_CBS1585 cds-NP_011623.3_CBS1585 99.9 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:692647-693789:- gene-YGR109C_CBS436 rna-NM_001181238.3_CBS436 cds-NP_011623.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:682690-683832:- gene-YGR109C_CBS6412 rna-NM_001181238.3_CBS6412 cds-NP_011623.3_CBS6412 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:687624-688766:- gene-YGR109C_CBS6413 rna-NM_001181238.3_CBS6413 cds-NP_011623.3_CBS6413 99.9 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:705055-706197:- gene-YGR109C_CENPK1137D rna-NM_001181238.3_CENPK1137D cds-NP_011623.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:677133-678275:- gene-YGR109C_EthanolRed rna-NM_001181238.3_EthanolRed cds-NP_011623.3_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:680924-682066:- gene-YGR109C_FaliES1 rna-NM_001181238.3_FaliES1 cds-NP_011623.3_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000114.1:683-1825:+ gene-YGR109C_JAY291 rna-NM_001181238.3_JAY291 cds-NP_011623.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:688714-689856:- gene-YGR109C_MUCL30387 rna-NM_001181238.3_MUCL30387 cds-NP_011623.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:691525-692667:- gene-YGR109C_MUCL30388 rna-NM_001181238.3_MUCL30388 cds-NP_011623.3_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:686748-687890:- gene-YGR109C_MUCL39482 rna-NM_001181238.3_MUCL39482 cds-NP_011623.3_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:696535-697677:- gene-YGR109C_MUCL42920 rna-NM_001181238.3_MUCL42920 cds-NP_011623.3_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:705359-706501:- gene-YGR109C_NCIM3186 rna-NM_001181238.3_NCIM3186 cds-NP_011623.3_NCIM3186 95.8 100.0 Verified 1 1 0 False False False True False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:681441-682583:- gene-YGR109C_NCYC1407 rna-NM_001181238.3_NCYC1407 cds-NP_011623.3_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:683609-684751:- gene-YGR109C_PE2H3 rna-NM_001181238.3_PE2H3 cds-NP_011623.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:688728-689870:- gene-YGR109C_PE2H4 rna-NM_001181238.3_PE2H4 cds-NP_011623.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:705359-706501:- gene-YGR109C_S288C rna-NM_001181238.3_S288C cds-NP_011623.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000015.1:132031-133173:- gene-YGR109C_SA1 rna-NM_001181238.3_SA1 cds-NP_011623.3_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:701304-702446:- gene-YGR109C_ThermosaccDry rna-NM_001181238.3_ThermosaccDry cds-NP_011623.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:797796-798938:- gene-YGR109C_VR1 rna-NM_001181238.3_VR1 cds-NP_011623.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:3699-4841:- gene-YGR109C_ZTW1 rna-NM_001181238.3_ZTW1 cds-NP_011623.3_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:691744-692887:- gene-YGR109C_Sparadoxus rna-NM_001181238.3_Sparadoxus cds-NP_011623.3_Sparadoxus 89.4 100.0 Verified 1 1 0 False False False True False

Additional files