CLB5 (YPR120C)


Gene profile

Gene name: CLB5
Reference locus (S288C): YPR120C
Gene biotype: protein_coding

Description: S-phase entry cyclin-5; B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase; CLB5 has a paralog, CLB6, that arose from the whole genome duplication

Top 10 interactors (score): SIC1 (0.999); CDC28 (0.999); CDC6 (0.997); CDC20 (0.996); CLB6 (0.985); MIH1 (0.982); CKS1 (0.979); ORC6 (0.967); KIN28 (0.964); SWE1 (0.964); CCL1 (0.96); SWI4 (0.959); SLD2 (0.952); CDH1 (0.947); FAR1 (0.942); TFB3 (0.939); PDS1 (0.929); CLN3 (0.925); SWI6 (0.923); ORC1 (0.906)

Homologues (species, bitscore): CCNB1 (Homo sapiens, 164.1); Ccnb2 (Mus musculus, 161.0); ccnb2 (Danio rerio, 163.3); ccnb1 (Xenopus tropicalis, 167.5); CycB (Drosophila melanogaster, 134.4); cyb-2.1 (Caenorhabditis elegans, 122.5); CYCB2;1 (Arabidopsis thaliana, 152.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:745354-746658:- gene-YPR120C_AKU4011 rna-NM_001184217.1_AKU4011 cds-NP_015445.1_AKU4011 99.3 99.7 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:150499-151806:+ gene-YPR120C_BG1 rna-NM_001184217.1_BG1 cds-NP_015445.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:826061-827368:- gene-YPR120C_Bruggeman rna-NM_001184217.1_Bruggeman cds-NP_015445.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:867654-868961:- gene-YPR120C_CAT1 rna-NM_001184217.1_CAT1 cds-NP_015445.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:749611-750915:- gene-YPR120C_CBS1585 rna-NM_001184217.1_CBS1585 cds-NP_015445.1_CBS1585 99.3 99.7 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:764261-765568:- gene-YPR120C_CBS436 rna-NM_001184217.1_CBS436 cds-NP_015445.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:752334-753638:- gene-YPR120C_CBS6412 rna-NM_001184217.1_CBS6412 cds-NP_015445.1_CBS6412 99.3 99.7 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:747057-748361:- gene-YPR120C_CBS6413 rna-NM_001184217.1_CBS6413 cds-NP_015445.1_CBS6413 99.3 99.7 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:773861-775168:- gene-YPR120C_CENPK1137D rna-NM_001184217.1_CENPK1137D cds-NP_015445.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:1071965-1073272:- gene-YPR120C_EthanolRed rna-NM_001184217.1_EthanolRed cds-NP_015445.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:751512-752819:- gene-YPR120C_FaliES1 rna-NM_001184217.1_FaliES1 cds-NP_015445.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000036.1:4551-5858:- gene-YPR120C_JAY291 rna-NM_001184217.1_JAY291 cds-NP_015445.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:766252-767559:- gene-YPR120C_MUCL30387 rna-NM_001184217.1_MUCL30387 cds-NP_015445.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:765030-766337:- gene-YPR120C_MUCL30388 rna-NM_001184217.1_MUCL30388 cds-NP_015445.1_MUCL30388 99.9 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:742118-743422:- gene-YPR120C_MUCL39482 rna-NM_001184217.1_MUCL39482 cds-NP_015445.1_MUCL39482 99.3 99.7 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:806004-807311:- gene-YPR120C_MUCL42920 rna-NM_001184217.1_MUCL42920 cds-NP_015445.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:773858-775165:- gene-YPR120C_NCIM3186 rna-NM_001184217.1_NCIM3186 cds-NP_015445.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:750711-752015:- gene-YPR120C_NCYC1407 rna-NM_001184217.1_NCYC1407 cds-NP_015445.1_NCYC1407 99.3 99.7 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:757638-758945:- gene-YPR120C_PE2H3 rna-NM_001184217.1_PE2H3 cds-NP_015445.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:757286-758593:- gene-YPR120C_PE2H4 rna-NM_001184217.1_PE2H4 cds-NP_015445.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:773875-775182:- gene-YPR120C_S288C rna-NM_001184217.1_S288C cds-NP_015445.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000028.1:71668-72975:- gene-YPR120C_SA1 rna-NM_001184217.1_SA1 cds-NP_015445.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:750957-752264:- gene-YPR120C_ThermosaccDry rna-NM_001184217.1_ThermosaccDry cds-NP_015445.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:768283-769593:- gene-YPR120C_VR1 rna-NM_001184217.1_VR1 cds-NP_015445.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:750354-751661:- gene-YPR120C_ZTW1 rna-NM_001184217.1_ZTW1 cds-NP_015445.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:752021-753316:- gene-YPR120C_Sparadoxus rna-NM_001184217.1_Sparadoxus cds-NP_015445.1_Sparadoxus 88.0 98.6 Verified 1 1 1 False True False False False

Additional files