Gene name: CLB4
Reference locus (S288C): YLR210W
Gene biotype: protein_coding
Description: G2/mitotic-specific cyclin-4; B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation; CLB4 has a paralog, CLB3, that arose from the whole genome duplication
Top 10 interactors (score): CDC28 (0.999); CKS1 (0.982); PHO85 (0.972); CDC20 (0.968); CDH1 (0.967); CDC5 (0.967); SIC1 (0.94); CIN8 (0.939); SWE1 (0.937); MIH1 (0.919); MAD2 (0.904); CDC6 (0.901); CLB3 (0.888); IPL1 (0.86); BUB1 (0.86); MAD3 (0.853); KAR9 (0.83); MCM2 (0.829); UBC11 (0.827); POL30 (0.824)
Homologues (species, bitscore): CCNB2 (Homo sapiens, 196.1); Ccnb1 (Mus musculus, 195.7); ccnb1 (Danio rerio, 189.1); ccnb2 (Xenopus tropicalis, 190.3); CycB (Drosophila melanogaster, 147.9); cyb-1 (Caenorhabditis elegans, 133.3); CYCB2;1 (Arabidopsis thaliana, 172.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:516161-517543:+ | gene-YLR210W_AKU4011 | rna-NM_001182097.1_AKU4011 | cds-NP_013311.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000177.1:73405-74787:+ | gene-YLR210W_BG1 | rna-NM_001182097.1_BG1 | cds-NP_013311.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:556385-557767:+ | gene-YLR210W_Bruggeman | rna-NM_001182097.1_Bruggeman | cds-NP_013311.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:556023-557405:+ | gene-YLR210W_CAT1 | rna-NM_001182097.1_CAT1 | cds-NP_013311.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:551653-553035:+ | gene-YLR210W_CBS1585 | rna-NM_001182097.1_CBS1585 | cds-NP_013311.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:541847-543229:+ | gene-YLR210W_CBS436 | rna-NM_001182097.1_CBS436 | cds-NP_013311.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:520215-521597:+ | gene-YLR210W_CBS6412 | rna-NM_001182097.1_CBS6412 | cds-NP_013311.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:551950-553332:+ | gene-YLR210W_CBS6413 | rna-NM_001182097.1_CBS6413 | cds-NP_013311.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:546653-548035:+ | gene-YLR210W_CENPK1137D | rna-NM_001182097.1_CENPK1137D | cds-NP_013311.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:515663-517045:+ | gene-YLR210W_EthanolRed | rna-NM_001182097.1_EthanolRed | cds-NP_013311.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:544590-545972:+ | gene-YLR210W_FaliES1 | rna-NM_001182097.1_FaliES1 | cds-NP_013311.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000004.1:71498-72880:+ | gene-YLR210W_JAY291 | rna-NM_001182097.1_JAY291 | cds-NP_013311.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:556436-557818:+ | gene-YLR210W_MUCL30387 | rna-NM_001182097.1_MUCL30387 | cds-NP_013311.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:561374-562756:+ | gene-YLR210W_MUCL30388 | rna-NM_001182097.1_MUCL30388 | cds-NP_013311.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:552636-554018:+ | gene-YLR210W_MUCL39482 | rna-NM_001182097.1_MUCL39482 | cds-NP_013311.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:553140-554522:+ | gene-YLR210W_MUCL42920 | rna-NM_001182097.1_MUCL42920 | cds-NP_013311.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:561982-563364:+ | gene-YLR210W_NCIM3186 | rna-NM_001182097.1_NCIM3186 | cds-NP_013311.1_NCIM3186 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:545055-546437:+ | gene-YLR210W_NCYC1407 | rna-NM_001182097.1_NCYC1407 | cds-NP_013311.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:549299-550681:+ | gene-YLR210W_PE2H3 | rna-NM_001182097.1_PE2H3 | cds-NP_013311.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:549043-550425:+ | gene-YLR210W_PE2H4 | rna-NM_001182097.1_PE2H4 | cds-NP_013311.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:562008-563390:+ | gene-YLR210W_S288C | rna-NM_001182097.1_S288C | cds-NP_013311.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000042.1:71541-72923:+ | gene-YLR210W_SA1 | rna-NM_001182097.1_SA1 | cds-NP_013311.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:547093-548475:+ | gene-YLR210W_ThermosaccDry | rna-NM_001182097.1_ThermosaccDry | cds-NP_013311.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:558434-559816:+ | gene-YLR210W_VR1 | rna-NM_001182097.1_VR1 | cds-NP_013311.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:71377-72759:+ | gene-YLR210W_ZTW1 | rna-NM_001182097.1_ZTW1 | cds-NP_013311.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:533181-534560:+ | gene-YLR210W_Sparadoxus | rna-NM_001182097.1_Sparadoxus | cds-NP_013311.1_Sparadoxus | 88.7 | 99.7 | Verified | 1 | 1 | 0 | False | False | True | False | False |