Gene name: CLB3
Reference locus (S288C): YDL155W
Gene biotype: protein_coding
Description: G2/mitotic-specific cyclin-3; B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation; relative distribution to the nucleus increases upon DNA replication stress; CLB3 has a paralog, CLB4, that arose from the whole genome duplication
Top 10 interactors (score): CDC28 (0.999); CKS1 (0.997); CDH1 (0.992); SIC1 (0.987); CDC5 (0.977); CDC20 (0.969); PHO85 (0.968); SWE1 (0.959); MIH1 (0.954); CDC6 (0.945); MAD2 (0.931); ASE1 (0.895); CLB4 (0.888); CDC14 (0.879); BUB1 (0.877); SWI5 (0.868); IPL1 (0.866); CIN8 (0.863); ESP1 (0.859); MAD3 (0.853)
Homologues (species, bitscore): CCNB2 (Homo sapiens, 208.4); Ccnb2 (Mus musculus, 208.4); ccnb2 (Danio rerio, 189.1); ccnb2 (Xenopus tropicalis, 189.1); CycB (Drosophila melanogaster, 153.7); cyb-3 (Caenorhabditis elegans, 138.7); CYCB2;3 (Arabidopsis thaliana, 172.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:161191-162474:+ | gene-YDL155W_AKU4011 | rna-NM_001180215.1_AKU4011 | cds-NP_010126.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:387304-388587:- | gene-YDL155W_BG1 | rna-NM_001180215.1_BG1 | cds-NP_010126.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:177239-178522:+ | gene-YDL155W_Bruggeman | rna-NM_001180215.1_Bruggeman | cds-NP_010126.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:175558-176841:+ | gene-YDL155W_CAT1 | rna-NM_001180215.1_CAT1 | cds-NP_010126.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:159222-160505:+ | gene-YDL155W_CBS1585 | rna-NM_001180215.1_CBS1585 | cds-NP_010126.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:176164-177447:+ | gene-YDL155W_CBS436 | rna-NM_001180215.1_CBS436 | cds-NP_010126.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:158475-159758:+ | gene-YDL155W_CBS6412 | rna-NM_001180215.1_CBS6412 | cds-NP_010126.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:177660-178943:+ | gene-YDL155W_CBS6413 | rna-NM_001180215.1_CBS6413 | cds-NP_010126.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:175425-176708:+ | gene-YDL155W_CENPK1137D | rna-NM_001180215.1_CENPK1137D | cds-NP_010126.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:172430-173713:+ | gene-YDL155W_EthanolRed | rna-NM_001180215.1_EthanolRed | cds-NP_010126.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:177962-179245:+ | gene-YDL155W_FaliES1 | rna-NM_001180215.1_FaliES1 | cds-NP_010126.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000032.1:40304-41587:- | gene-YDL155W_JAY291 | rna-NM_001180215.1_JAY291 | cds-NP_010126.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:176353-177636:+ | gene-YDL155W_MUCL30387 | rna-NM_001180215.1_MUCL30387 | cds-NP_010126.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:167214-168497:+ | gene-YDL155W_MUCL30388 | rna-NM_001180215.1_MUCL30388 | cds-NP_010126.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:160377-161660:+ | gene-YDL155W_MUCL39482 | rna-NM_001180215.1_MUCL39482 | cds-NP_010126.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | MBVV01000307.1:7730-9013:- | gene-YDL155W_MUCL42920 | rna-NM_001180215.1_MUCL42920 | cds-NP_010126.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:176696-177979:+ | gene-YDL155W_NCIM3186 | rna-NM_001180215.1_NCIM3186 | cds-NP_010126.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:160310-161593:+ | gene-YDL155W_NCYC1407 | rna-NM_001180215.1_NCYC1407 | cds-NP_010126.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:167551-168834:+ | gene-YDL155W_PE2H3 | rna-NM_001180215.1_PE2H3 | cds-NP_010126.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:167555-168838:+ | gene-YDL155W_PE2H4 | rna-NM_001180215.1_PE2H4 | cds-NP_010126.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:176773-178056:+ | gene-YDL155W_S288C | rna-NM_001180215.1_S288C | cds-NP_010126.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000043.1:42335-43618:+ | gene-YDL155W_SA1 | rna-NM_001180215.1_SA1 | cds-NP_010126.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:177723-179006:+ | gene-YDL155W_ThermosaccDry | rna-NM_001180215.1_ThermosaccDry | cds-NP_010126.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:178321-179604:+ | gene-YDL155W_VR1 | rna-NM_001180215.1_VR1 | cds-NP_010126.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:175850-177133:+ | gene-YDL155W_ZTW1 | rna-NM_001180215.1_ZTW1 | cds-NP_010126.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:177987-179276:+ | gene-YDL155W_Sparadoxus | rna-NM_001180215.1_Sparadoxus | cds-NP_010126.1_Sparadoxus | 89.0 | 99.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |