Gene name: CLB2
Reference locus (S288C): YPR119W
Gene biotype: protein_coding
Description: G2/mitotic-specific cyclin-2; B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome; CLB2 has a paralog, CLB1, that arose from the whole genome duplication
Top 10 interactors (score): CDC6 (0.999); CDC28 (0.999); SWE1 (0.999); SIC1 (0.999); CDH1 (0.999); CDC20 (0.998); MIH1 (0.998); CKS1 (0.998); CDC5 (0.998); SWI5 (0.993); CDC23 (0.987); CDC14 (0.986); CIN8 (0.986); ESP1 (0.986); PHO85 (0.981); CDC27 (0.979); MAD2 (0.977); FKH2 (0.976); KIN28 (0.975); CDC15 (0.975)
Homologues (species, bitscore): CCNB2 (Homo sapiens, 214.5); Ccnb2 (Mus musculus, 218.4); ccnb1 (Danio rerio, 196.1); ccnb2 (Xenopus tropicalis, 209.5); CycB (Drosophila melanogaster, 163.3); cyb-3 (Caenorhabditis elegans, 116.3); CYCB2;2 (Arabidopsis thaliana, 157.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:743131-744606:+ | gene-YPR119W_AKU4011 | rna-NM_001184216.1_AKU4011 | cds-NP_015444.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:152553-154028:- | gene-YPR119W_BG1 | rna-NM_001184216.1_BG1 | cds-NP_015444.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:823838-825313:+ | gene-YPR119W_Bruggeman | rna-NM_001184216.1_Bruggeman | cds-NP_015444.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:865432-866907:+ | gene-YPR119W_CAT1 | rna-NM_001184216.1_CAT1 | cds-NP_015444.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:747388-748863:+ | gene-YPR119W_CBS1585 | rna-NM_001184216.1_CBS1585 | cds-NP_015444.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:762039-763514:+ | gene-YPR119W_CBS436 | rna-NM_001184216.1_CBS436 | cds-NP_015444.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:750111-751586:+ | gene-YPR119W_CBS6412 | rna-NM_001184216.1_CBS6412 | cds-NP_015444.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:744834-746309:+ | gene-YPR119W_CBS6413 | rna-NM_001184216.1_CBS6413 | cds-NP_015444.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:771639-773114:+ | gene-YPR119W_CENPK1137D | rna-NM_001184216.1_CENPK1137D | cds-NP_015444.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1069743-1071218:+ | gene-YPR119W_EthanolRed | rna-NM_001184216.1_EthanolRed | cds-NP_015444.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:749290-750765:+ | gene-YPR119W_FaliES1 | rna-NM_001184216.1_FaliES1 | cds-NP_015444.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000036.1:2330-3805:+ | gene-YPR119W_JAY291 | rna-NM_001184216.1_JAY291 | cds-NP_015444.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:764029-765504:+ | gene-YPR119W_MUCL30387 | rna-NM_001184216.1_MUCL30387 | cds-NP_015444.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:762807-764282:+ | gene-YPR119W_MUCL30388 | rna-NM_001184216.1_MUCL30388 | cds-NP_015444.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:739895-741370:+ | gene-YPR119W_MUCL39482 | rna-NM_001184216.1_MUCL39482 | cds-NP_015444.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:803781-805256:+ | gene-YPR119W_MUCL42920 | rna-NM_001184216.1_MUCL42920 | cds-NP_015444.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:771636-773111:+ | gene-YPR119W_NCIM3186 | rna-NM_001184216.1_NCIM3186 | cds-NP_015444.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:748488-749963:+ | gene-YPR119W_NCYC1407 | rna-NM_001184216.1_NCYC1407 | cds-NP_015444.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:755416-756891:+ | gene-YPR119W_PE2H3 | rna-NM_001184216.1_PE2H3 | cds-NP_015444.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:755064-756539:+ | gene-YPR119W_PE2H4 | rna-NM_001184216.1_PE2H4 | cds-NP_015444.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:771653-773128:+ | gene-YPR119W_S288C | rna-NM_001184216.1_S288C | cds-NP_015444.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000028.1:69446-70921:+ | gene-YPR119W_SA1 | rna-NM_001184216.1_SA1 | cds-NP_015444.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:748735-750210:+ | gene-YPR119W_ThermosaccDry | rna-NM_001184216.1_ThermosaccDry | cds-NP_015444.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:766061-767536:+ | gene-YPR119W_VR1 | rna-NM_001184216.1_VR1 | cds-NP_015444.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:748131-749606:+ | gene-YPR119W_ZTW1 | rna-NM_001184216.1_ZTW1 | cds-NP_015444.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:749814-751289:+ | gene-YPR119W_Sparadoxus | rna-NM_001184216.1_Sparadoxus | cds-NP_015444.1_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |