Gene name: CLB1
Reference locus (S288C): YGR108W
Gene biotype: protein_coding
Description: G2/mitotic-specific cyclin-1; B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome; CLB1 has a paralog, CLB2, that arose from the whole genome duplication
Top 10 interactors (score): CDC28 (0.999); CKS1 (0.998); SWE1 (0.996); PHO85 (0.996); CDC6 (0.996); MIH1 (0.995); CDC5 (0.99); SIC1 (0.99); CDH1 (0.987); CDC20 (0.984); KIN28 (0.973); CCL1 (0.972); CLB2 (0.97); SWI5 (0.97); AMA1 (0.953); CLN2 (0.953); CTK2 (0.948); TFB3 (0.941); PHO80 (0.924); CAK1 (0.921)
Homologues (species, bitscore): CCNB2 (Homo sapiens, 199.5); Ccnb2 (Mus musculus, 199.9); ccnb2 (Danio rerio, 184.1); ccnb2 (Xenopus tropicalis, 198.4); CycB (Drosophila melanogaster, 152.9); cyb-2.1 (Caenorhabditis elegans, 107.1); CYC3B (Arabidopsis thaliana, 145.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:688307-689722:+ | gene-YGR108W_AKU4011 | rna-NM_001181237.1_AKU4011 | cds-NP_011622.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:123662-125077:+ | gene-YGR108W_BG1 | rna-NM_001181237.1_BG1 | cds-NP_011622.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:689992-691407:+ | gene-YGR108W_Bruggeman | rna-NM_001181237.1_Bruggeman | cds-NP_011622.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:688195-689610:+ | gene-YGR108W_CAT1 | rna-NM_001181237.1_CAT1 | cds-NP_011622.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:689297-690712:+ | gene-YGR108W_CBS1585 | rna-NM_001181237.1_CBS1585 | cds-NP_011622.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:690924-692339:+ | gene-YGR108W_CBS436 | rna-NM_001181237.1_CBS436 | cds-NP_011622.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:680966-682381:+ | gene-YGR108W_CBS6412 | rna-NM_001181237.1_CBS6412 | cds-NP_011622.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:685900-687315:+ | gene-YGR108W_CBS6413 | rna-NM_001181237.1_CBS6413 | cds-NP_011622.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:703332-704747:+ | gene-YGR108W_CENPK1137D | rna-NM_001181237.1_CENPK1137D | cds-NP_011622.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:675409-676824:+ | gene-YGR108W_EthanolRed | rna-NM_001181237.1_EthanolRed | cds-NP_011622.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:679200-680615:+ | gene-YGR108W_FaliES1 | rna-NM_001181237.1_FaliES1 | cds-NP_011622.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000114.1:2133-3547:- | gene-YGR108W_JAY291 | rna-NM_001181237.1_JAY291 | cds-NP_011622.1_JAY291 | 99.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:686992-688407:+ | gene-YGR108W_MUCL30387 | rna-NM_001181237.1_MUCL30387 | cds-NP_011622.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:689803-691218:+ | gene-YGR108W_MUCL30388 | rna-NM_001181237.1_MUCL30388 | cds-NP_011622.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:685024-686439:+ | gene-YGR108W_MUCL39482 | rna-NM_001181237.1_MUCL39482 | cds-NP_011622.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:694813-696228:+ | gene-YGR108W_MUCL42920 | rna-NM_001181237.1_MUCL42920 | cds-NP_011622.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:703636-705051:+ | gene-YGR108W_NCIM3186 | rna-NM_001181237.1_NCIM3186 | cds-NP_011622.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:679717-681132:+ | gene-YGR108W_NCYC1407 | rna-NM_001181237.1_NCYC1407 | cds-NP_011622.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:681886-683301:+ | gene-YGR108W_PE2H3 | rna-NM_001181237.1_PE2H3 | cds-NP_011622.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:687005-688420:+ | gene-YGR108W_PE2H4 | rna-NM_001181237.1_PE2H4 | cds-NP_011622.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:703636-705051:+ | gene-YGR108W_S288C | rna-NM_001181237.1_S288C | cds-NP_011622.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:130308-131723:+ | gene-YGR108W_SA1 | rna-NM_001181237.1_SA1 | cds-NP_011622.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:699580-700995:+ | gene-YGR108W_ThermosaccDry | rna-NM_001181237.1_ThermosaccDry | cds-NP_011622.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:796073-797488:+ | gene-YGR108W_VR1 | rna-NM_001181237.1_VR1 | cds-NP_011622.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:1975-3390:+ | gene-YGR108W_ZTW1 | rna-NM_001181237.1_ZTW1 | cds-NP_011622.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:690020-691438:+ | gene-YGR108W_Sparadoxus | rna-NM_001181237.1_Sparadoxus | cds-NP_011622.1_Sparadoxus | 89.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |