Gene name: CKI1
Reference locus (S288C): YLR133W
Gene biotype: protein_coding
Description: Choline kinase; catalyzes the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway); exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; CKI1 has a paralog, EKI1, that arose from the whole genome duplication
Top 10 interactors (score): PCT1 (0.992); GDE1 (0.927); SEC14 (0.919); OPI3 (0.899); ECT1 (0.893); EPT1 (0.886); CPT1 (0.879); CHO2 (0.859); EKI1 (0.849); DGK1 (0.826); PSD1 (0.794); SPO14 (0.782); CHO1 (0.766); CDC28 (0.764); PHO80 (0.76); NAP1 (0.757); SIC1 (0.748); CLB5 (0.747); HNM1 (0.722); PIS1 (0.721)
Homologues (species, bitscore): CHKB (Homo sapiens, 119.4); Chkb (Mus musculus, 115.5); chkb (Danio rerio, 101.7); chka (Xenopus tropicalis, 100.9); CG2201 (Drosophila melanogaster, 108.6); cka-2 (Caenorhabditis elegans, 115.2); AT1G74320 (Arabidopsis thaliana, 140.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:390925-392673:+ | gene-YLR133W_AKU4011 | rna-NM_001182020.1_AKU4011 | cds-NP_013234.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:354709-356457:+ | gene-YLR133W_BG1 | rna-NM_001182020.1_BG1 | cds-NP_013234.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:402808-404556:+ | gene-YLR133W_Bruggeman | rna-NM_001182020.1_Bruggeman | cds-NP_013234.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:402218-403966:+ | gene-YLR133W_CAT1 | rna-NM_001182020.1_CAT1 | cds-NP_013234.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:398069-399817:+ | gene-YLR133W_CBS1585 | rna-NM_001182020.1_CBS1585 | cds-NP_013234.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:388309-390057:+ | gene-YLR133W_CBS436 | rna-NM_001182020.1_CBS436 | cds-NP_013234.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:396486-398234:+ | gene-YLR133W_CBS6412 | rna-NM_001182020.1_CBS6412 | cds-NP_013234.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:398334-400082:+ | gene-YLR133W_CBS6413 | rna-NM_001182020.1_CBS6413 | cds-NP_013234.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:393467-395215:+ | gene-YLR133W_CENPK1137D | rna-NM_001182020.1_CENPK1137D | cds-NP_013234.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:391126-392874:+ | gene-YLR133W_EthanolRed | rna-NM_001182020.1_EthanolRed | cds-NP_013234.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:390637-392385:+ | gene-YLR133W_FaliES1 | rna-NM_001182020.1_FaliES1 | cds-NP_013234.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000117.1:806-2554:- | gene-YLR133W_JAY291 | rna-NM_001182020.1_JAY291 | cds-NP_013234.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:402800-404548:+ | gene-YLR133W_MUCL30387 | rna-NM_001182020.1_MUCL30387 | cds-NP_013234.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:407618-409366:+ | gene-YLR133W_MUCL30388 | rna-NM_001182020.1_MUCL30388 | cds-NP_013234.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:398578-400326:+ | gene-YLR133W_MUCL39482 | rna-NM_001182020.1_MUCL39482 | cds-NP_013234.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:398708-400456:+ | gene-YLR133W_MUCL42920 | rna-NM_001182020.1_MUCL42920 | cds-NP_013234.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:408419-410167:+ | gene-YLR133W_NCIM3186 | rna-NM_001182020.1_NCIM3186 | cds-NP_013234.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:390850-392598:+ | gene-YLR133W_NCYC1407 | rna-NM_001182020.1_NCYC1407 | cds-NP_013234.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:396419-398167:+ | gene-YLR133W_PE2H3 | rna-NM_001182020.1_PE2H3 | cds-NP_013234.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:396160-397908:+ | gene-YLR133W_PE2H4 | rna-NM_001182020.1_PE2H4 | cds-NP_013234.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:408445-410193:+ | gene-YLR133W_S288C | rna-NM_001182020.1_S288C | cds-NP_013234.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000055.1:34356-36104:+ | gene-YLR133W_SA1 | rna-NM_001182020.1_SA1 | cds-NP_013234.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:391847-393595:+ | gene-YLR133W_ThermosaccDry | rna-NM_001182020.1_ThermosaccDry | cds-NP_013234.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:404560-406308:+ | gene-YLR133W_VR1 | rna-NM_001182020.1_VR1 | cds-NP_013234.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:389645-391393:+ | gene-YLR133W_ZTW1 | rna-NM_001182020.1_ZTW1 | cds-NP_013234.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:399748-401496:+ | gene-YLR133W_Sparadoxus | rna-NM_001182020.1_Sparadoxus | cds-NP_013234.1_Sparadoxus | 90.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |