CKA2 (YOR061W)


Gene profile

Gene name: CKA2
Reference locus (S288C): YOR061W
Gene biotype: protein_coding

Description: Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching

Top 10 interactors (score): CKB1 (0.999); CKA1 (0.999); CKB2 (0.999); UTP22 (0.995); POB3 (0.993); UTP4 (0.992); NOP19 (0.991); SPT16 (0.99); UTP10 (0.979); NAN1 (0.978); UTP18 (0.978); RRP7 (0.978); UTP6 (0.977); UTP8 (0.977); UTP13 (0.977); IMP4 (0.977); UTP9 (0.977); UTP21 (0.977); NAP1 (0.977); MPP10 (0.977)

Homologues (species, bitscore): CSNK2A1 (Homo sapiens, 409.5); Csnk2a1 (Mus musculus, 409.8); ck2a1 (Danio rerio, 405.6); csnk2a2 (Xenopus tropicalis, 394.8); CkIIalpha (Drosophila melanogaster, 399.4); kin-3 (Caenorhabditis elegans, 397.1); AT2G23070 (Arabidopsis thaliana, 417.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:425871-426890:+ gene-YOR061W_AKU4011 rna-NM_001183480.1_AKU4011 cds-NP_014704.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000088.1:5869-6888:- gene-YOR061W_BG1 rna-NM_001183480.1_BG1 cds-NP_014704.1_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:428583-429602:+ gene-YOR061W_Bruggeman rna-NM_001183480.1_Bruggeman cds-NP_014704.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:427331-428350:+ gene-YOR061W_CAT1 rna-NM_001183480.1_CAT1 cds-NP_014704.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:420557-421576:+ gene-YOR061W_CBS1585 rna-NM_001183480.1_CBS1585 cds-NP_014704.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:424864-425883:+ gene-YOR061W_CBS436 rna-NM_001183480.1_CBS436 cds-NP_014704.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:419884-420903:+ gene-YOR061W_CBS6412 rna-NM_001183480.1_CBS6412 cds-NP_014704.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:427168-428187:+ gene-YOR061W_CBS6413 rna-NM_001183480.1_CBS6413 cds-NP_014704.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:441518-442537:+ gene-YOR061W_CENPK1137D rna-NM_001183480.1_CENPK1137D cds-NP_014704.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:422586-423605:+ gene-YOR061W_EthanolRed rna-NM_001183480.1_EthanolRed cds-NP_014704.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:425922-426941:+ gene-YOR061W_FaliES1 rna-NM_001183480.1_FaliES1 cds-NP_014704.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000407.1:17423-18442:- gene-YOR061W_JAY291 rna-NM_001183480.1_JAY291 cds-NP_014704.1_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:433372-434391:+ gene-YOR061W_MUCL30387 rna-NM_001183480.1_MUCL30387 cds-NP_014704.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:437775-438794:+ gene-YOR061W_MUCL30388 rna-NM_001183480.1_MUCL30388 cds-NP_014704.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:428042-429061:+ gene-YOR061W_MUCL39482 rna-NM_001183480.1_MUCL39482 cds-NP_014704.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:443189-444208:+ gene-YOR061W_MUCL42920 rna-NM_001183480.1_MUCL42920 cds-NP_014704.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:441423-442442:+ gene-YOR061W_NCIM3186 rna-NM_001183480.1_NCIM3186 cds-NP_014704.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:434960-435979:+ gene-YOR061W_NCYC1407 rna-NM_001183480.1_NCYC1407 cds-NP_014704.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:433568-434587:+ gene-YOR061W_PE2H3 rna-NM_001183480.1_PE2H3 cds-NP_014704.1_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:443949-444968:+ gene-YOR061W_PE2H4 rna-NM_001183480.1_PE2H4 cds-NP_014704.1_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:441534-442553:+ gene-YOR061W_S288C rna-NM_001183480.1_S288C cds-NP_014704.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:409797-410816:+ gene-YOR061W_SA1 rna-NM_001183480.1_SA1 cds-NP_014704.1_SA1 99.9 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:425070-426089:+ gene-YOR061W_ThermosaccDry rna-NM_001183480.1_ThermosaccDry cds-NP_014704.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:426334-427353:+ gene-YOR061W_VR1 rna-NM_001183480.1_VR1 cds-NP_014704.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:159076-160095:+ gene-YOR061W_ZTW1 rna-NM_001183480.1_ZTW1 cds-NP_014704.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:430631-431650:+ gene-YOR061W_Sparadoxus rna-NM_001183480.1_Sparadoxus cds-NP_014704.1_Sparadoxus 94.4 100.0 Verified 1 1 1 False True False False False

Additional files