Gene name: CIT1
Reference locus (S288C): YNR001C
Gene biotype: protein_coding
Description: Citrate synthase, mitochondrial; Citrate synthase; catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein; CIT1 has a paralog, CIT2, that arose from the whole genome duplication
Top 10 interactors (score): IDH1 (0.999); ACO1 (0.999); CIT3 (0.999); MDH1 (0.999); IDH2 (0.998); CIT2 (0.995); FUM1 (0.994); MDH3 (0.992); ATP2 (0.991); ATP1 (0.991); MDH2 (0.99); ACS1 (0.99); ACO2 (0.988); MLS1 (0.988); LAT1 (0.987); LYS12 (0.985); LSC1 (0.981); PDB1 (0.975); ACS2 (0.974); KGD1 (0.973)
Homologues (species, bitscore): CS (Homo sapiens, 602.1); Cs (Mus musculus, 593.2); cs (Danio rerio, 587.8); cs (Xenopus tropicalis, 584.3); kdn (Drosophila melanogaster, 584.7); cts-1 (Caenorhabditis elegans, 563.5); ATCS (Arabidopsis thaliana, 549.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:612723-614162:- | gene-YNR001C_AKU4011 | rna-NM_001183178.1_AKU4011 | cds-NP_014398.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:515151-516590:- | gene-YNR001C_BG1 | rna-NM_001183178.1_BG1 | cds-NP_014398.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:629539-630978:- | gene-YNR001C_Bruggeman | rna-NM_001183178.1_Bruggeman | cds-NP_014398.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:664923-666362:- | gene-YNR001C_CAT1 | rna-NM_001183178.1_CAT1 | cds-NP_014398.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:618420-619859:- | gene-YNR001C_CBS1585 | rna-NM_001183178.1_CBS1585 | cds-NP_014398.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:680441-681880:- | gene-YNR001C_CBS436 | rna-NM_001183178.1_CBS436 | cds-NP_014398.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:608228-609667:- | gene-YNR001C_CBS6412 | rna-NM_001183178.1_CBS6412 | cds-NP_014398.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:609391-610830:- | gene-YNR001C_CBS6413 | rna-NM_001183178.1_CBS6413 | cds-NP_014398.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:623272-624711:- | gene-YNR001C_CENPK1137D | rna-NM_001183178.1_CENPK1137D | cds-NP_014398.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:614791-616230:- | gene-YNR001C_EthanolRed | rna-NM_001183178.1_EthanolRed | cds-NP_014398.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:605560-606999:- | gene-YNR001C_FaliES1 | rna-NM_001183178.1_FaliES1 | cds-NP_014398.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000008.1:983-2422:+ | gene-YNR001C_JAY291 | rna-NM_001183178.1_JAY291 | cds-NP_014398.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:627629-629068:- | gene-YNR001C_MUCL30387 | rna-NM_001183178.1_MUCL30387 | cds-NP_014398.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:668461-669900:- | gene-YNR001C_MUCL30388 | rna-NM_001183178.1_MUCL30388 | cds-NP_014398.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:609928-611367:- | gene-YNR001C_MUCL39482 | rna-NM_001183178.1_MUCL39482 | cds-NP_014398.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:613723-615162:- | gene-YNR001C_MUCL42920 | rna-NM_001183178.1_MUCL42920 | cds-NP_014398.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:629591-631030:- | gene-YNR001C_NCIM3186 | rna-NM_001183178.1_NCIM3186 | cds-NP_014398.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:612180-613619:- | gene-YNR001C_NCYC1407 | rna-NM_001183178.1_NCYC1407 | cds-NP_014398.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:614101-615540:- | gene-YNR001C_PE2H3 | rna-NM_001183178.1_PE2H3 | cds-NP_014398.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:615419-616858:- | gene-YNR001C_PE2H4 | rna-NM_001183178.1_PE2H4 | cds-NP_014398.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:629622-631061:- | gene-YNR001C_S288C | rna-NM_001183178.1_S288C | cds-NP_014398.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000068.1:27326-28765:- | gene-YNR001C_SA1 | rna-NM_001183178.1_SA1 | cds-NP_014398.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:605900-607339:- | gene-YNR001C_ThermosaccDry | rna-NM_001183178.1_ThermosaccDry | cds-NP_014398.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:648446-649885:- | gene-YNR001C_VR1 | rna-NM_001183178.1_VR1 | cds-NP_014398.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:514712-516151:- | gene-YNR001C_ZTW1 | rna-NM_001183178.1_ZTW1 | cds-NP_014398.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:620964-622403:- | gene-YNR001C_Sparadoxus | rna-NM_001183178.1_Sparadoxus | cds-NP_014398.1_Sparadoxus | 93.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |