Gene name: CIR2
Reference locus (S288C): YOR356W
Gene biotype: protein_coding
Description: Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Putative ortholog of human ETF-dH; found in a large supramolecular complex with other mitochondrial dehydrogenases; may have a role in oxidative stress response; ETF-dH is also known as electron transfer flavoprotein dehydrogenase
Top 10 interactors (score): CIR1 (0.999); AIM45 (0.999); DLD2 (0.887); COQ1 (0.855); AIF1 (0.834); SPS19 (0.815); ZTA1 (0.799); NDE1 (0.794); FAD1 (0.778); NDE2 (0.763); COQ2 (0.761); DLD1 (0.759); YAT1 (0.757); LIP5 (0.757); COQ6 (0.742); MET12 (0.734); NDI1 (0.727); FRD1 (0.726); COQ9 (0.709); COQ5 (0.702)
Homologues (species, bitscore): ETFDH (Homo sapiens, 583.2); Etfdh (Mus musculus, 582.8); etfdh (Danio rerio, 570.1); etfdh (Xenopus tropicalis, 499.2); Etf-QO (Drosophila melanogaster, 544.7); let-721 (Caenorhabditis elegans, 557.4); ETFQO (Arabidopsis thaliana, 516.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:993805-995700:+ | gene-YOR356W_AKU4011 | rna-NM_001183776.1_AKU4011 | cds-NP_015001.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000078.1:30981-32876:+ | gene-YOR356W_BG1 | rna-NM_001183776.1_BG1 | cds-NP_015001.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:978622-980517:+ | gene-YOR356W_Bruggeman | rna-NM_001183776.1_Bruggeman | cds-NP_015001.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:978450-980345:+ | gene-YOR356W_CAT1 | rna-NM_001183776.1_CAT1 | cds-NP_015001.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:978215-980110:+ | gene-YOR356W_CBS1585 | rna-NM_001183776.1_CBS1585 | cds-NP_015001.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:973028-974923:+ | gene-YOR356W_CBS436 | rna-NM_001183776.1_CBS436 | cds-NP_015001.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:207517-209412:+ | gene-YOR356W_CBS6412 | rna-NM_001183776.1_CBS6412 | cds-NP_015001.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:982488-984383:+ | gene-YOR356W_CBS6413 | rna-NM_001183776.1_CBS6413 | cds-NP_015001.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:1007043-1008938:+ | gene-YOR356W_CENPK1137D | rna-NM_001183776.1_CENPK1137D | cds-NP_015001.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:222514-224409:+ | gene-YOR356W_EthanolRed | rna-NM_001183776.1_EthanolRed | cds-NP_015001.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:975343-977238:+ | gene-YOR356W_FaliES1 | rna-NM_001183776.1_FaliES1 | cds-NP_015001.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:28436-30331:- | gene-YOR356W_JAY291 | rna-NM_001183776.1_JAY291 | cds-NP_015001.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:987950-989845:+ | gene-YOR356W_MUCL30387 | rna-NM_001183776.1_MUCL30387 | cds-NP_015001.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:995964-997859:+ | gene-YOR356W_MUCL30388 | rna-NM_001183776.1_MUCL30388 | cds-NP_015001.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:984750-986645:+ | gene-YOR356W_MUCL39482 | rna-NM_001183776.1_MUCL39482 | cds-NP_015001.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:992356-994251:+ | gene-YOR356W_MUCL42920 | rna-NM_001183776.1_MUCL42920 | cds-NP_015001.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:1007110-1009005:+ | gene-YOR356W_NCIM3186 | rna-NM_001183776.1_NCIM3186 | cds-NP_015001.1_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:985758-987653:+ | gene-YOR356W_NCYC1407 | rna-NM_001183776.1_NCYC1407 | cds-NP_015001.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:981018-982913:+ | gene-YOR356W_PE2H3 | rna-NM_001183776.1_PE2H3 | cds-NP_015001.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:997369-999264:+ | gene-YOR356W_PE2H4 | rna-NM_001183776.1_PE2H4 | cds-NP_015001.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:1007221-1009116:+ | gene-YOR356W_S288C | rna-NM_001183776.1_S288C | cds-NP_015001.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:111752-113647:+ | gene-YOR356W_SA1 | rna-NM_001183776.1_SA1 | cds-NP_015001.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:974513-976408:+ | gene-YOR356W_ThermosaccDry | rna-NM_001183776.1_ThermosaccDry | cds-NP_015001.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:1035768-1037663:+ | gene-YOR356W_VR1 | rna-NM_001183776.1_VR1 | cds-NP_015001.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:707243-709138:+ | gene-YOR356W_ZTW1 | rna-NM_001183776.1_ZTW1 | cds-NP_015001.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:980730-982625:+ | gene-YOR356W_Sparadoxus | rna-NM_001183776.1_Sparadoxus | cds-NP_015001.1_Sparadoxus | 89.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |