Gene name: CIP1
Reference locus (S288C): YPL014W
Gene biotype: protein_coding
Description: Uncharacterized protein YPL014W; Cyclin-dependent kinase inhibitor; interacts with and inhibits the Cdc28p/Cln2p, G1/S phase cyclin-dependent kinase complex but not S-phase, or M-phase complexes; overexpression blocks cells in G1 phase and stabilizes the Cdc28p inhibitor Sic1p, while disruption accelerates the G1/S phase transition; phosphorylated during S phase in a Cdc28p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus
Top 10 interactors (score): CDC28 (0.873); CLN2 (0.835); YDR246W-A (0.76); YER084W (0.707); BSC6 (0.695); YFL064C (0.695); BOP2 (0.691); CLN3 (0.669); CKS1 (0.665); NTE1 (0.651); YGR017W (0.651); YML133C (0.62); YOP1 (0.59); YHL049C (0.573); YBL111C (0.572); ADA2 (0.571); CHS7 (0.571); RNH203 (0.568); IES5 (0.567); RGI2 (0.526)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:499039-500184:+ | gene-YPL014W_AKU4011 | rna-NM_001183828.1_AKU4011 | cds-NP_015311.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:397121-398266:- | gene-YPL014W_BG1 | rna-NM_001183828.1_BG1 | cds-NP_015311.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:575973-577118:+ | gene-YPL014W_Bruggeman | rna-NM_001183828.1_Bruggeman | cds-NP_015311.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:618432-619577:+ | gene-YPL014W_CAT1 | rna-NM_001183828.1_CAT1 | cds-NP_015311.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:503201-504346:+ | gene-YPL014W_CBS1585 | rna-NM_001183828.1_CBS1585 | cds-NP_015311.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:517238-518383:+ | gene-YPL014W_CBS436 | rna-NM_001183828.1_CBS436 | cds-NP_015311.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:506953-508098:+ | gene-YPL014W_CBS6412 | rna-NM_001183828.1_CBS6412 | cds-NP_015311.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:499676-500821:+ | gene-YPL014W_CBS6413 | rna-NM_001183828.1_CBS6413 | cds-NP_015311.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:527554-528699:+ | gene-YPL014W_CENPK1137D | rna-NM_001183828.1_CENPK1137D | cds-NP_015311.1_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:497460-498605:+ | gene-YPL014W_EthanolRed | rna-NM_001183828.1_EthanolRed | cds-NP_015311.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:505290-506435:+ | gene-YPL014W_FaliES1 | rna-NM_001183828.1_FaliES1 | cds-NP_015311.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000283.1:113832-114977:+ | gene-YPL014W_JAY291 | rna-NM_001183828.1_JAY291 | cds-NP_015311.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:516923-518068:+ | gene-YPL014W_MUCL30387 | rna-NM_001183828.1_MUCL30387 | cds-NP_015311.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:516030-517175:+ | gene-YPL014W_MUCL30388 | rna-NM_001183828.1_MUCL30388 | cds-NP_015311.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:496441-497586:+ | gene-YPL014W_MUCL39482 | rna-NM_001183828.1_MUCL39482 | cds-NP_015311.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:555514-556659:+ | gene-YPL014W_MUCL42920 | rna-NM_001183828.1_MUCL42920 | cds-NP_015311.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:527530-528675:+ | gene-YPL014W_NCIM3186 | rna-NM_001183828.1_NCIM3186 | cds-NP_015311.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:503715-504860:+ | gene-YPL014W_NCYC1407 | rna-NM_001183828.1_NCYC1407 | cds-NP_015311.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:510359-511504:+ | gene-YPL014W_PE2H3 | rna-NM_001183828.1_PE2H3 | cds-NP_015311.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:509974-511119:+ | gene-YPL014W_PE2H4 | rna-NM_001183828.1_PE2H4 | cds-NP_015311.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:527547-528692:+ | gene-YPL014W_S288C | rna-NM_001183828.1_S288C | cds-NP_015311.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000076.1:24278-25423:+ | gene-YPL014W_SA1 | rna-NM_001183828.1_SA1 | cds-NP_015311.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:505089-506234:+ | gene-YPL014W_ThermosaccDry | rna-NM_001183828.1_ThermosaccDry | cds-NP_015311.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:520460-521605:+ | gene-YPL014W_VR1 | rna-NM_001183828.1_VR1 | cds-NP_015311.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:504375-505520:+ | gene-YPL014W_ZTW1 | rna-NM_001183828.1_ZTW1 | cds-NP_015311.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:504259-505404:+ | gene-YPL014W_Sparadoxus | rna-NM_001183828.1_Sparadoxus | cds-NP_015311.1_Sparadoxus | 89.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |