CIN5 (YOR028C)


Gene profile

Gene name: CIN5
Reference locus (S288C): YOR028C
Gene biotype: protein_coding

Description: Basic leucine zipper (bZIP) transcription factor of the yAP-1 family; physically interacts with the Tup1-Cyc8 complex and recruits Tup1p to its targets; mediates pleiotropic drug resistance and salt tolerance; nuclearly localized under oxidative stress and sequestered in the cytoplasm by Lot6p under reducing conditions; CIN5 has a paralog, YAP6, that arose from the whole genome duplication

Top 10 interactors (score): YAP7 (0.813); YAP1 (0.813); SKN7 (0.813); SKO1 (0.789); SOK2 (0.787); NRG1 (0.779); MSN2 (0.779); MSN4 (0.758); YAP5 (0.748); GCN4 (0.746); RPN4 (0.736); FMP48 (0.73); CUP9 (0.718); XBP1 (0.717); ROX1 (0.715); STE12 (0.713); CAD1 (0.711); PHD1 (0.711); TEC1 (0.7); SWI4 (0.697)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:367745-368632:- gene-YOR028C_AKU4011 rna-NM_001183447.1_AKU4011 cds-NP_014671.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000152.1:183323-184210:- gene-YOR028C_BG1 rna-NM_001183447.1_BG1 cds-NP_014671.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:370488-371375:- gene-YOR028C_Bruggeman rna-NM_001183447.1_Bruggeman cds-NP_014671.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:368642-369529:- gene-YOR028C_CAT1 rna-NM_001183447.1_CAT1 cds-NP_014671.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:362437-363324:- gene-YOR028C_CBS1585 rna-NM_001183447.1_CBS1585 cds-NP_014671.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:366792-367679:- gene-YOR028C_CBS436 rna-NM_001183447.1_CBS436 cds-NP_014671.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:361790-362677:- gene-YOR028C_CBS6412 rna-NM_001183447.1_CBS6412 cds-NP_014671.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:369166-370053:- gene-YOR028C_CBS6413 rna-NM_001183447.1_CBS6413 cds-NP_014671.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:383417-384305:- gene-YOR028C_CENPK1137D rna-NM_001183447.1_CENPK1137D cds-NP_014671.1_CENPK1137D 99.3 100.0 Unannotated 1 1 0 False False False True False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:364446-365333:- gene-YOR028C_EthanolRed rna-NM_001183447.1_EthanolRed cds-NP_014671.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:367794-368681:- gene-YOR028C_FaliES1 rna-NM_001183447.1_FaliES1 cds-NP_014671.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000035.1:38439-39326:- gene-YOR028C_JAY291 rna-NM_001183447.1_JAY291 cds-NP_014671.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:374875-375762:- gene-YOR028C_MUCL30387 rna-NM_001183447.1_MUCL30387 cds-NP_014671.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:378310-379197:- gene-YOR028C_MUCL30388 rna-NM_001183447.1_MUCL30388 cds-NP_014671.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:369920-370807:- gene-YOR028C_MUCL39482 rna-NM_001183447.1_MUCL39482 cds-NP_014671.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:384733-385620:- gene-YOR028C_MUCL42920 rna-NM_001183447.1_MUCL42920 cds-NP_014671.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:383422-384309:- gene-YOR028C_NCIM3186 rna-NM_001183447.1_NCIM3186 cds-NP_014671.1_NCIM3186 98.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:376622-377509:- gene-YOR028C_NCYC1407 rna-NM_001183447.1_NCYC1407 cds-NP_014671.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:375459-376346:- gene-YOR028C_PE2H3 rna-NM_001183447.1_PE2H3 cds-NP_014671.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:385838-386725:- gene-YOR028C_PE2H4 rna-NM_001183447.1_PE2H4 cds-NP_014671.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:383533-384420:- gene-YOR028C_S288C rna-NM_001183447.1_S288C cds-NP_014671.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000001.1:351326-352213:- gene-YOR028C_SA1 rna-NM_001183447.1_SA1 cds-NP_014671.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:366334-367221:- gene-YOR028C_ThermosaccDry rna-NM_001183447.1_ThermosaccDry cds-NP_014671.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:367223-368110:- gene-YOR028C_VR1 rna-NM_001183447.1_VR1 cds-NP_014671.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:100962-101849:- gene-YOR028C_ZTW1 rna-NM_001183447.1_ZTW1 cds-NP_014671.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:373493-374380:- gene-YOR028C_Sparadoxus rna-NM_001183447.1_Sparadoxus cds-NP_014671.1_Sparadoxus 87.3 100.0 Verified 1 1 1 False True False False False

Additional files