Gene name: CIA2
Reference locus (S288C): YHR122W
Gene biotype: protein_coding
Description: MIP18 family protein YHR122W; Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at a late step of Fe-S cluster assembly; forms the CIA targeting complex with Cia1p and Met18p that directs Fe-S cluster incorporation into a subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, and telomere maintenance; ortholog of human FAM96B
Top 10 interactors (score): CIA1 (0.999); RAD3 (0.999); MET18 (0.999); NAR1 (0.996); NBP35 (0.996); CFD1 (0.992); DNA2 (0.975); POL3 (0.956); DRE2 (0.949); TAH18 (0.906); YAE1 (0.863); LTO1 (0.846); ATM1 (0.812); ISA1 (0.789); RLI1 (0.762); JAC1 (0.734); GRX5 (0.638); GRX3 (0.633); BUD20 (0.606); IBA57 (0.584)
Homologues (species, bitscore): FAM96B (Homo sapiens, 140.6); Fam96b (Mus musculus, 142.1); fam96b (Danio rerio, 138.3); fam96b (Xenopus tropicalis, 117.1); CG7949 (Drosophila melanogaster, 139.8); F45G2.10 (Caenorhabditis elegans, 124.4); AE7 (Arabidopsis thaliana, 116.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:340551-341246:+ | gene-YHR122W_AKU4011 | rna-NM_001179252.1_AKU4011 | cds-NP_011990.1_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:176626-177321:- | gene-YHR122W_BG1 | rna-NM_001179252.1_BG1 | cds-NP_011990.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:347842-348537:+ | gene-YHR122W_Bruggeman | rna-NM_001179252.1_Bruggeman | cds-NP_011990.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:342979-343674:+ | gene-YHR122W_CAT1 | rna-NM_001179252.1_CAT1 | cds-NP_011990.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:339575-340270:+ | gene-YHR122W_CBS1585 | rna-NM_001179252.1_CBS1585 | cds-NP_011990.1_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:336934-337629:+ | gene-YHR122W_CBS436 | rna-NM_001179252.1_CBS436 | cds-NP_011990.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:341013-341708:+ | gene-YHR122W_CBS6412 | rna-NM_001179252.1_CBS6412 | cds-NP_011990.1_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:340602-341297:+ | gene-YHR122W_CBS6413 | rna-NM_001179252.1_CBS6413 | cds-NP_011990.1_CBS6413 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:346799-347494:+ | gene-YHR122W_CENPK1137D | rna-NM_001179252.1_CENPK1137D | cds-NP_011990.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:399456-400151:+ | gene-YHR122W_EthanolRed | rna-NM_001179252.1_EthanolRed | cds-NP_011990.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:340944-341639:+ | gene-YHR122W_FaliES1 | rna-NM_001179252.1_FaliES1 | cds-NP_011990.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000139.1:13560-14255:+ | gene-YHR122W_JAY291 | rna-NM_001179252.1_JAY291 | cds-NP_011990.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:347572-348267:+ | gene-YHR122W_MUCL30387 | rna-NM_001179252.1_MUCL30387 | cds-NP_011990.1_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:347219-347914:+ | gene-YHR122W_MUCL30388 | rna-NM_001179252.1_MUCL30388 | cds-NP_011990.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:339914-340609:+ | gene-YHR122W_MUCL39482 | rna-NM_001179252.1_MUCL39482 | cds-NP_011990.1_MUCL39482 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:346154-346849:+ | gene-YHR122W_MUCL42920 | rna-NM_001179252.1_MUCL42920 | cds-NP_011990.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:353507-354202:+ | gene-YHR122W_NCIM3186 | rna-NM_001179252.1_NCIM3186 | cds-NP_011990.1_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:342124-342819:+ | gene-YHR122W_NCYC1407 | rna-NM_001179252.1_NCYC1407 | cds-NP_011990.1_NCYC1407 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:341576-342271:+ | gene-YHR122W_PE2H3 | rna-NM_001179252.1_PE2H3 | cds-NP_011990.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:349003-349698:+ | gene-YHR122W_PE2H4 | rna-NM_001179252.1_PE2H4 | cds-NP_011990.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:353625-354320:+ | gene-YHR122W_S288C | rna-NM_001179252.1_S288C | cds-NP_011990.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000014.1:4650-5345:- | gene-YHR122W_SA1 | rna-NM_001179252.1_SA1 | cds-NP_011990.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:342027-342722:+ | gene-YHR122W_ThermosaccDry | rna-NM_001179252.1_ThermosaccDry | cds-NP_011990.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:349648-350343:+ | gene-YHR122W_VR1 | rna-NM_001179252.1_VR1 | cds-NP_011990.1_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:333038-333733:+ | gene-YHR122W_ZTW1 | rna-NM_001179252.1_ZTW1 | cds-NP_011990.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:338723-339418:+ | gene-YHR122W_Sparadoxus | rna-NM_001179252.1_Sparadoxus | cds-NP_011990.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |