Gene name: CIA1
Reference locus (S288C): YDR267C
Gene biotype: protein_coding
Description: Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at late step of Fe-S cluster assembly; forms CIA targeting complex with Cia2p and Met18p that directs Fe-S cluster incorporation into subset of proteins involved in methionine biosynthesis, DNA replication and repair, transcription, telomere maintenance; contains WD40 repeats; human homolog CIAO1 can complement yeast cia1 null mutant
Top 10 interactors (score): CIA2 (0.999); MET18 (0.999); NAR1 (0.985); NBP35 (0.983); RAD3 (0.977); CFD1 (0.976); POL3 (0.967); DNA2 (0.943); DRE2 (0.899); TAH18 (0.848); CDC40 (0.827); GID7 (0.778); ATM1 (0.763); MDV1 (0.757); ARC40 (0.745); NUP84 (0.71); RLI1 (0.703); ISD11 (0.691); JAC1 (0.685); SWD1 (0.635)
Homologues (species, bitscore): CIAO1 (Homo sapiens, 241.9); Ciao1 (Mus musculus, 240.7); ciao1 (Danio rerio, 231.9); ciao1 (Xenopus tropicalis, 240.7); Ciao1 (Drosophila melanogaster, 206.1); Y18D10A.9 (Caenorhabditis elegans, 146.0); emb1345 (Arabidopsis thaliana, 198.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:954803-955795:- | gene-YDR267C_AKU4011 | rna-NM_001180575.3_AKU4011 | cds-NP_010553.3_AKU4011 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:176534-177526:+ | gene-YDR267C_BG1 | rna-NM_001180575.3_BG1 | cds-NP_010553.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:980975-981967:- | gene-YDR267C_Bruggeman | rna-NM_001180575.3_Bruggeman | cds-NP_010553.3_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:968819-969811:- | gene-YDR267C_CAT1 | rna-NM_001180575.3_CAT1 | cds-NP_010553.3_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:949248-950240:- | gene-YDR267C_CBS1585 | rna-NM_001180575.3_CBS1585 | cds-NP_010553.3_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:967281-968273:- | gene-YDR267C_CBS436 | rna-NM_001180575.3_CBS436 | cds-NP_010553.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:945931-946923:- | gene-YDR267C_CBS6412 | rna-NM_001180575.3_CBS6412 | cds-NP_010553.3_CBS6412 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:967167-968159:- | gene-YDR267C_CBS6413 | rna-NM_001180575.3_CBS6413 | cds-NP_010553.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1001153-1002145:- | gene-YDR267C_CENPK1137D | rna-NM_001180575.3_CENPK1137D | cds-NP_010553.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:953349-954341:- | gene-YDR267C_EthanolRed | rna-NM_001180575.3_EthanolRed | cds-NP_010553.3_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:961551-962543:- | gene-YDR267C_FaliES1 | rna-NM_001180575.3_FaliES1 | cds-NP_010553.3_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000176.1:9805-10797:- | gene-YDR267C_JAY291 | rna-NM_001180575.3_JAY291 | cds-NP_010553.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:966611-967603:- | gene-YDR267C_MUCL30387 | rna-NM_001180575.3_MUCL30387 | cds-NP_010553.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:954320-955312:- | gene-YDR267C_MUCL30388 | rna-NM_001180575.3_MUCL30388 | cds-NP_010553.3_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:941054-942046:- | gene-YDR267C_MUCL39482 | rna-NM_001180575.3_MUCL39482 | cds-NP_010553.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:881050-882042:- | gene-YDR267C_MUCL42920 | rna-NM_001180575.3_MUCL42920 | cds-NP_010553.3_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1002433-1003425:- | gene-YDR267C_NCIM3186 | rna-NM_001180575.3_NCIM3186 | cds-NP_010553.3_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:954344-955336:- | gene-YDR267C_NCYC1407 | rna-NM_001180575.3_NCYC1407 | cds-NP_010553.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:964976-965968:- | gene-YDR267C_PE2H3 | rna-NM_001180575.3_PE2H3 | cds-NP_010553.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:970250-971242:- | gene-YDR267C_PE2H4 | rna-NM_001180575.3_PE2H4 | cds-NP_010553.3_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1002510-1003502:- | gene-YDR267C_S288C | rna-NM_001180575.3_S288C | cds-NP_010553.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000102.1:10131-11123:- | gene-YDR267C_SA1 | rna-NM_001180575.3_SA1 | cds-NP_010553.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:965836-966828:- | gene-YDR267C_ThermosaccDry | rna-NM_001180575.3_ThermosaccDry | cds-NP_010553.3_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:981430-982422:- | gene-YDR267C_VR1 | rna-NM_001180575.3_VR1 | cds-NP_010553.3_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:9963-10955:- | gene-YDR267C_ZTW1 | rna-NM_001180575.3_ZTW1 | cds-NP_010553.3_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:962247-963239:- | gene-YDR267C_Sparadoxus | rna-NM_001180575.3_Sparadoxus | cds-NP_010553.3_Sparadoxus | 92.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |