Gene name: CHS3
Reference locus (S288C): YBR023C
Gene biotype: protein_coding
Description: Chitin synthase III; catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan; contains overlapping di-leucine and di-acidic signals that mediate, respectively, intracellular trafficking by AP-1 and trafficking to plasma membrane by exomer complex; requires AP-3 complex for its intracellular retention
Top 10 interactors (score): SKT5 (0.998); CHS6 (0.998); CHS5 (0.994); CHS7 (0.979); QRI1 (0.969); FKS1 (0.964); BNI4 (0.947); CHS2 (0.937); BCH2 (0.916); GAS1 (0.915); CHS1 (0.897); GFA1 (0.879); BCH1 (0.87); SMI1 (0.864); PFA4 (0.858); MYO1 (0.847); BUD7 (0.826); ENT5 (0.825); SHC1 (0.823); KRE6 (0.781)
Homologues (species, bitscore): HAS2 (Homo sapiens, 68.2); Has1 (Mus musculus, 68.2); chs1 (Danio rerio, 75.5); has3 (Xenopus tropicalis, 64.3); kkv (Drosophila melanogaster, 85.1); chs-1 (Caenorhabditis elegans, 91.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:266856-270353:- | gene-YBR023C_AKU4011 | rna-NM_001178371.1_AKU4011 | cds-NP_009579.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:257008-260505:- | gene-YBR023C_BG1 | rna-NM_001178371.1_BG1 | cds-NP_009579.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:267588-271085:- | gene-YBR023C_Bruggeman | rna-NM_001178371.1_Bruggeman | cds-NP_009579.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:269884-273381:- | gene-YBR023C_CAT1 | rna-NM_001178371.1_CAT1 | cds-NP_009579.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:258893-262390:- | gene-YBR023C_CBS1585 | rna-NM_001178371.1_CBS1585 | cds-NP_009579.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:267162-270659:- | gene-YBR023C_CBS436 | rna-NM_001178371.1_CBS436 | cds-NP_009579.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:357397-360894:- | gene-YBR023C_CBS6412 | rna-NM_001178371.1_CBS6412 | cds-NP_009579.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:264261-267758:- | gene-YBR023C_CBS6413 | rna-NM_001178371.1_CBS6413 | cds-NP_009579.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:278176-281673:- | gene-YBR023C_CENPK1137D | rna-NM_001178371.1_CENPK1137D | cds-NP_009579.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:393868-397365:- | gene-YBR023C_EthanolRed | rna-NM_001178371.1_EthanolRed | cds-NP_009579.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:281964-285461:- | gene-YBR023C_FaliES1 | rna-NM_001178371.1_FaliES1 | cds-NP_009579.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000048.1:12133-15630:+ | gene-YBR023C_JAY291 | rna-NM_001178371.1_JAY291 | cds-NP_009579.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:268187-271684:- | gene-YBR023C_MUCL30387 | rna-NM_001178371.1_MUCL30387 | cds-NP_009579.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:268441-271938:- | gene-YBR023C_MUCL30388 | rna-NM_001178371.1_MUCL30388 | cds-NP_009579.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:258875-262372:- | gene-YBR023C_MUCL39482 | rna-NM_001178371.1_MUCL39482 | cds-NP_009579.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:266330-269827:- | gene-YBR023C_MUCL42920 | rna-NM_001178371.1_MUCL42920 | cds-NP_009579.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:284225-287722:- | gene-YBR023C_NCIM3186 | rna-NM_001178371.1_NCIM3186 | cds-NP_009579.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:260052-263549:- | gene-YBR023C_NCYC1407 | rna-NM_001178371.1_NCYC1407 | cds-NP_009579.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:272233-275730:- | gene-YBR023C_PE2H3 | rna-NM_001178371.1_PE2H3 | cds-NP_009579.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:269901-273398:- | gene-YBR023C_PE2H4 | rna-NM_001178371.1_PE2H4 | cds-NP_009579.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:284428-287925:- | gene-YBR023C_S288C | rna-NM_001178371.1_S288C | cds-NP_009579.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000037.1:20779-24276:+ | gene-YBR023C_SA1 | rna-NM_001178371.1_SA1 | cds-NP_009579.1_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:281673-285170:- | gene-YBR023C_ThermosaccDry | rna-NM_001178371.1_ThermosaccDry | cds-NP_009579.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:263585-267082:- | gene-YBR023C_VR1 | rna-NM_001178371.1_VR1 | cds-NP_009579.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:257652-261149:- | gene-YBR023C_ZTW1 | rna-NM_001178371.1_ZTW1 | cds-NP_009579.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:293833-297339:- | gene-YBR023C_Sparadoxus | rna-NM_001178371.1_Sparadoxus | cds-NP_009579.1_Sparadoxus | 91.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |