Gene name: CHL4
Reference locus (S288C): YDR254W
Gene biotype: protein_coding
Description: Central kinetochore subunit CHL4; Outer kinetochore protein required for chromosome stability; involved in new kinetochore assembly and sister chromatid cohesion; forms a stable complex with Iml3p; peripheral component of the Ctf19 kinetochore complex that interacts with Ctf19p, Ctf3p, and Mif2p; required for the spindle assembly checkpoint; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-N and fission yeast mis15
Top 10 interactors (score): IML3 (0.999); CTF19 (0.997); CTF3 (0.996); OKP1 (0.996); MCM16 (0.995); CSE4 (0.994); NKP2 (0.992); MCM22 (0.992); MIF2 (0.988); AME1 (0.987); MCM21 (0.986); NKP1 (0.984); DSN1 (0.977); MTW1 (0.976); DAM1 (0.968); DUO1 (0.959); DAD4 (0.957); SPC19 (0.95); SPC34 (0.95); CBF2 (0.941)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:921442-922818:+ | gene-YDR254W_AKU4011 | rna-NM_001180562.3_AKU4011 | cds-NP_010540.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:202488-203864:- | gene-YDR254W_BG1 | rna-NM_001180562.3_BG1 | cds-NP_010540.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:953771-955147:+ | gene-YDR254W_Bruggeman | rna-NM_001180562.3_Bruggeman | cds-NP_010540.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:941055-942431:+ | gene-YDR254W_CAT1 | rna-NM_001180562.3_CAT1 | cds-NP_010540.3_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:911791-913167:+ | gene-YDR254W_CBS1585 | rna-NM_001180562.3_CBS1585 | cds-NP_010540.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:941349-942725:+ | gene-YDR254W_CBS436 | rna-NM_001180562.3_CBS436 | cds-NP_010540.3_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:908551-909927:+ | gene-YDR254W_CBS6412 | rna-NM_001180562.3_CBS6412 | cds-NP_010540.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:939645-941021:+ | gene-YDR254W_CBS6413 | rna-NM_001180562.3_CBS6413 | cds-NP_010540.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:964038-965414:+ | gene-YDR254W_CENPK1137D | rna-NM_001180562.3_CENPK1137D | cds-NP_010540.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:922110-923486:+ | gene-YDR254W_EthanolRed | rna-NM_001180562.3_EthanolRed | cds-NP_010540.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:930312-931688:+ | gene-YDR254W_FaliES1 | rna-NM_001180562.3_FaliES1 | cds-NP_010540.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000261.1:18845-20221:+ | gene-YDR254W_JAY291 | rna-NM_001180562.3_JAY291 | cds-NP_010540.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:939669-941045:+ | gene-YDR254W_MUCL30387 | rna-NM_001180562.3_MUCL30387 | cds-NP_010540.3_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:927699-929075:+ | gene-YDR254W_MUCL30388 | rna-NM_001180562.3_MUCL30388 | cds-NP_010540.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:913196-914572:+ | gene-YDR254W_MUCL39482 | rna-NM_001180562.3_MUCL39482 | cds-NP_010540.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:852960-854336:+ | gene-YDR254W_MUCL42920 | rna-NM_001180562.3_MUCL42920 | cds-NP_010540.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:965036-966412:+ | gene-YDR254W_NCIM3186 | rna-NM_001180562.3_NCIM3186 | cds-NP_010540.3_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:916865-918241:+ | gene-YDR254W_NCYC1407 | rna-NM_001180562.3_NCYC1407 | cds-NP_010540.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:933122-934498:+ | gene-YDR254W_PE2H3 | rna-NM_001180562.3_PE2H3 | cds-NP_010540.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:938399-939775:+ | gene-YDR254W_PE2H4 | rna-NM_001180562.3_PE2H4 | cds-NP_010540.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:965113-966489:+ | gene-YDR254W_S288C | rna-NM_001180562.3_S288C | cds-NP_010540.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:170959-172335:+ | gene-YDR254W_SA1 | rna-NM_001180562.3_SA1 | cds-NP_010540.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:928466-929842:+ | gene-YDR254W_ThermosaccDry | rna-NM_001180562.3_ThermosaccDry | cds-NP_010540.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:943722-945098:+ | gene-YDR254W_VR1 | rna-NM_001180562.3_VR1 | cds-NP_010540.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:191210-192586:+ | gene-YDR254W_ZTW1 | rna-NM_001180562.3_ZTW1 | cds-NP_010540.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:933861-935237:+ | gene-YDR254W_Sparadoxus | rna-NM_001180562.3_Sparadoxus | cds-NP_010540.3_Sparadoxus | 88.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |