Gene name: CHL1
Reference locus (S288C): YPL008W
Gene biotype: protein_coding
Description: Chromosome transmission fidelity protein 1; Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity and interstrand cross-link repair; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome; Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily
Top 10 interactors (score): CTF18 (0.995); CTF4 (0.995); ECO1 (0.991); TOF1 (0.976); RAD27 (0.973); CTF8 (0.959); DCC1 (0.958); SMC3 (0.958); CTF3 (0.924); ELG1 (0.923); MRC1 (0.917); CSM3 (0.912); SRS2 (0.907); MCD1 (0.896); CHL4 (0.895); MAD2 (0.875); RAD61 (0.871); SCC2 (0.866); MCM21 (0.85); MCM22 (0.835)
Homologues (species, bitscore): DDX11 (Homo sapiens, 379.0); Ddx11 (Mus musculus, 437.6); ddx11 (Danio rerio, 441.4); ddx11 (Xenopus tropicalis, 459.1); CG11403 (Drosophila melanogaster, 375.2); chl-1 (Caenorhabditis elegans, 348.2); AT1G79890 (Arabidopsis thaliana, 402.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:510841-513426:+ | gene-YPL008W_AKU4011 | rna-NM_001183822.1_AKU4011 | cds-NP_015317.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:383747-386332:- | gene-YPL008W_BG1 | rna-NM_001183822.1_BG1 | cds-NP_015317.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:587784-590369:+ | gene-YPL008W_Bruggeman | rna-NM_001183822.1_Bruggeman | cds-NP_015317.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:630530-633115:+ | gene-YPL008W_CAT1 | rna-NM_001183822.1_CAT1 | cds-NP_015317.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:515018-517603:+ | gene-YPL008W_CBS1585 | rna-NM_001183822.1_CBS1585 | cds-NP_015317.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:529086-531671:+ | gene-YPL008W_CBS436 | rna-NM_001183822.1_CBS436 | cds-NP_015317.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:518767-521352:+ | gene-YPL008W_CBS6412 | rna-NM_001183822.1_CBS6412 | cds-NP_015317.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:511478-514063:+ | gene-YPL008W_CBS6413 | rna-NM_001183822.1_CBS6413 | cds-NP_015317.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:539386-541971:+ | gene-YPL008W_CENPK1137D | rna-NM_001183822.1_CENPK1137D | cds-NP_015317.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:509265-511850:+ | gene-YPL008W_EthanolRed | rna-NM_001183822.1_EthanolRed | cds-NP_015317.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:517095-519680:+ | gene-YPL008W_FaliES1 | rna-NM_001183822.1_FaliES1 | cds-NP_015317.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000341.1:18333-20918:- | gene-YPL008W_JAY291 | rna-NM_001183822.1_JAY291 | cds-NP_015317.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:528737-531322:+ | gene-YPL008W_MUCL30387 | rna-NM_001183822.1_MUCL30387 | cds-NP_015317.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:527841-530426:+ | gene-YPL008W_MUCL30388 | rna-NM_001183822.1_MUCL30388 | cds-NP_015317.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:508258-510843:+ | gene-YPL008W_MUCL39482 | rna-NM_001183822.1_MUCL39482 | cds-NP_015317.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:567355-569940:+ | gene-YPL008W_MUCL42920 | rna-NM_001183822.1_MUCL42920 | cds-NP_015317.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:539368-541953:+ | gene-YPL008W_NCIM3186 | rna-NM_001183822.1_NCIM3186 | cds-NP_015317.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:515517-518102:+ | gene-YPL008W_NCYC1407 | rna-NM_001183822.1_NCYC1407 | cds-NP_015317.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:522217-524802:+ | gene-YPL008W_PE2H3 | rna-NM_001183822.1_PE2H3 | cds-NP_015317.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:521832-524417:+ | gene-YPL008W_PE2H4 | rna-NM_001183822.1_PE2H4 | cds-NP_015317.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:539385-541970:+ | gene-YPL008W_S288C | rna-NM_001183822.1_S288C | cds-NP_015317.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000076.1:36126-38711:+ | gene-YPL008W_SA1 | rna-NM_001183822.1_SA1 | cds-NP_015317.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:516894-519479:+ | gene-YPL008W_ThermosaccDry | rna-NM_001183822.1_ThermosaccDry | cds-NP_015317.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:532292-534877:+ | gene-YPL008W_VR1 | rna-NM_001183822.1_VR1 | cds-NP_015317.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:516200-518785:+ | gene-YPL008W_ZTW1 | rna-NM_001183822.1_ZTW1 | cds-NP_015317.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:516028-518613:+ | gene-YPL008W_Sparadoxus | rna-NM_001183822.1_Sparadoxus | cds-NP_015317.1_Sparadoxus | 89.1 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |