CHA1 (YCL064C)


Gene profile

Gene name: CHA1
Reference locus (S288C): YCL064C
Gene biotype: protein_coding

Description: Catabolic L-serine/threonine dehydratase; Catabolic L-serine (L-threonine) deaminase; catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine; Belongs to the serine/threonine dehydratase family

Top 10 interactors (score): LEU2 (0.973); THR4 (0.973); TRP5 (0.965); ILV6 (0.962); ILV2 (0.958); GLY1 (0.95); SHM1 (0.948); SHM2 (0.944); AGX1 (0.939); HOM6 (0.933); CYS4 (0.931); SER2 (0.927); THR1 (0.923); BAT2 (0.918); DSD1 (0.912); BAT1 (0.908); CHO1 (0.9); MET6 (0.896); ILV1 (0.877); GLO1 (0.856)

Homologues (species, bitscore): SDSL (Homo sapiens, 188.3); Sdsl (Mus musculus, 204.9); SDSL (Danio rerio, 175.6); sdsl (Xenopus tropicalis, 212.2); CG8129 (Drosophila melanogaster, 95.9); K01C8.1 (Caenorhabditis elegans, 89.0); OMR1 (Arabidopsis thaliana, 88.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:17089-18171:- gene-YCL064C_AKU4011 rna-NM_001178706.1_AKU4011 cds-NP_001018030.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000090.1:2009-3091:- gene-YCL064C_BG1 rna-NM_001178706.1_BG1 cds-NP_001018030.1_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:3925-5007:- gene-YCL064C_Bruggeman rna-NM_001178706.1_Bruggeman cds-NP_001018030.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:16972-18054:- gene-YCL064C_CAT1 rna-NM_001178706.1_CAT1 cds-NP_001018030.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:17772-18854:- gene-YCL064C_CBS1585 rna-NM_001178706.1_CBS1585 cds-NP_001018030.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:16320-17402:- gene-YCL064C_CBS436 rna-NM_001178706.1_CBS436 cds-NP_001018030.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:5530-6612:- gene-YCL064C_CBS6412 rna-NM_001178706.1_CBS6412 cds-NP_001018030.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:16544-17626:- gene-YCL064C_CBS6413 rna-NM_001178706.1_CBS6413 cds-NP_001018030.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:15392-16474:- gene-YCL064C_CENPK1137D rna-NM_001178706.1_CENPK1137D cds-NP_001018030.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:15318-16400:- gene-YCL064C_EthanolRed rna-NM_001178706.1_EthanolRed cds-NP_001018030.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:16080-17162:- gene-YCL064C_FaliES1 rna-NM_001178706.1_FaliES1 cds-NP_001018030.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000225.1:67170-68252:+ gene-YCL064C_JAY291 rna-NM_001178706.1_JAY291 cds-NP_001018030.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:3505-4587:- gene-YCL064C_MUCL30387 rna-NM_001178706.1_MUCL30387 cds-NP_001018030.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:3804-4886:- gene-YCL064C_MUCL30388 rna-NM_001178706.1_MUCL30388 cds-NP_001018030.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:18159-19241:- gene-YCL064C_MUCL39482 rna-NM_001178706.1_MUCL39482 cds-NP_001018030.1_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:4081-5163:- gene-YCL064C_MUCL42920 rna-NM_001178706.1_MUCL42920 cds-NP_001018030.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:15430-16512:- gene-YCL064C_NCIM3186 rna-NM_001178706.1_NCIM3186 cds-NP_001018030.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:18484-19566:- gene-YCL064C_NCYC1407 rna-NM_001178706.1_NCYC1407 cds-NP_001018030.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:16255-17337:- gene-YCL064C_PE2H3 rna-NM_001178706.1_PE2H3 cds-NP_001018030.1_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:16212-17294:- gene-YCL064C_PE2H4 rna-NM_001178706.1_PE2H4 cds-NP_001018030.1_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:15798-16880:- gene-YCL064C_S288C rna-NM_001178706.1_S288C cds-NP_001018030.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000061.1:2946-4028:- gene-YCL064C_SA1 rna-NM_001178706.1_SA1 cds-NP_001018030.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:16399-17481:- gene-YCL064C_ThermosaccDry rna-NM_001178706.1_ThermosaccDry cds-NP_001018030.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:21693-22775:- gene-YCL064C_VR1 rna-NM_001178706.1_VR1 cds-NP_001018030.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:16627-17709:- gene-YCL064C_ZTW1 rna-NM_001178706.1_ZTW1 cds-NP_001018030.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:46336-47418:- gene-YCL064C_Sparadoxus rna-NM_001178706.1_Sparadoxus cds-NP_001018030.1_Sparadoxus 89.8 100.0 Verified 1 1 1 False True False False False

Additional files